IrisPlex: A sensitive DNA tool for accurate prediction of blue and brown eye colour in the absence of ancestry information

Kayser, 2009, DNA-based prediction of human externally visible characteristics in forensics: motivations, scientific challenges, and ethical considerations, Forensic Sci. Int. Genet., 3, 154, 10.1016/j.fsigen.2009.01.012

Sulem, 2007, Genetic determinants of hair, eye and skin pigmentation in Europeans, Nat. Genet., 39, 1443, 10.1038/ng.2007.13

Eiberg, 2008, Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression, Hum. Genet., 123, 177, 10.1007/s00439-007-0460-x

Kayser, 2008, Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene, Am. J. Hum. Genet., 82, 411, 10.1016/j.ajhg.2007.10.003

Sturm, 2008, A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color, Am. J. Hum. Genet., 82, 424, 10.1016/j.ajhg.2007.11.005

Han, 2008, A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation, PLoS Genet., 4, e1000074, 10.1371/journal.pgen.1000074

Sulem, 2008, Two newly identified genetic determinants of pigmentation in Europeans, Nat. Genet., 40, 835, 10.1038/ng.160

Kanetsky, 2002, A polymorphism in the Agouti signaling protein gene Is associated with human pigmentation, Am. J. Hum. Genet., 70, 770, 10.1086/339076

Rebbeck, 2002, P gene as an inherited biomarker of human eye color, Cancer Epidemiol. Biomarkers Prev., 11, 782

Liu, 2009, Eye color and the prediction of complex phenotypes from genotypes, Curr. Biol., 19, R192, 10.1016/j.cub.2009.01.027

Beals, 1965

Sturm, 2004, Eye colour: portals into pigmentation genes and ancestry, Trends Genet., 20, 327, 10.1016/j.tig.2004.06.010

Frost, 2006, European hair and eye color: a case of frequency-dependent sexual selection?, Evol. Hum. Behav., 27, 85, 10.1016/j.evolhumbehav.2005.07.002

Duffy, 2007, A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation, Am. J. Hum. Genet., 80, 241, 10.1086/510885

Zhu, 2004, A genome scan for eye color in 502 twin families: most variation is due to a QTL on chromosome 15q, Twin Res., 7, 197, 10.1375/136905204323016186

Posthuma, 2006, Replicated linkage for eye color on 15q using comparative ratings of sibling pairs, Behav. Genet., 36, 12, 10.1007/s10519-005-9007-x

Frudakis, 2003, Sequences associated with human iris pigmentation, Genetics, 165, 2071, 10.1093/genetics/165.4.2071

Brilliant, 2001, The mouse p (pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2), and melanosomal pH, Pigment Cell Res., 14, 86, 10.1034/j.1600-0749.2001.140203.x

Sturm, 2009, Molecular genetics of human pigmentation diversity, Hum. Mol. Genet., 18, R9, 10.1093/hmg/ddp003

Rosenberg, 2006, Standardized subsets of the HGDP-CEPH Human Genome Diversity Cell Line Panel, accounting for atypical and duplicated samples and pairs of close relatives, Ann. Hum. Genet., 70, 841, 10.1111/j.1469-1809.2006.00285.x

Rosenberg, 2002, Genetic structure of human populations, Science, 298, 2381, 10.1126/science.1078311

Untergasser, 2007, Primer3Plus, an enhanced web interface to Primer3, Nucleic Acids Res., 35, W71, 10.1093/nar/gkm306

Altschul, 1997, Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res., 25, 3389, 10.1093/nar/25.17.3389

Sherry, 2001, dbSNP: the NCBI database of genetic variation, Nucleic Acids Res., 29, 308, 10.1093/nar/29.1.308

Vallone, 2004, AutoDimer: a screening tool for primer-dimer and hairpin structures, Biotechniques, 37, 226, 10.2144/04372ST03

Weir, 1984, Estimating F-statistics for the analysis of population structure, Evolution, 38, 1358, 10.2307/2408641

Excoffier, 1992, Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data, Genetics, 131, 479, 10.1093/genetics/131.2.479

Excoffier, 2005, Arlequin (version 3.0): an integrated software package for population genetics data analysis, Evol. Bioinform. Online, 1, 47, 10.1177/117693430500100003

Sanchez, 2006, A multiplex assay with 52 single nucleotide polymorphisms for human identification, Electrophoresis, 27, 1713, 10.1002/elps.200500671

Dixon, 2005, Validation of a 21-locus autosomal SNP multiplex for forensic identification purposes, Forensic Sci. Int., 154, 62, 10.1016/j.forsciint.2004.12.011

Mulero, 2008, Development and validation of the AmpFlSTR MiniFiler PCR Amplification Kit: a MiniSTR multiplex for the analysis of degraded and/or PCR inhibited DNA, J. Forensic Sci., 53, 838, 10.1111/j.1556-4029.2008.00760.x

Bito, 1997, Eye color changes past early childhood: the Louisville twin study, Arch. Ophthalmol., 115, 659, 10.1001/archopht.1997.01100150661017

Iida, 2009, Genotyping of five single nucleotide polymorphisms in the OCA2 and HERC2 genes associated with blue-brown eye color in the Japanese population, Cell Biochem. Funct., 27, 323, 10.1002/cbf.1572

Pulker, 2007, Finding genes that underlie physical traits of forensic interest using genetic tools, Forensic Sci. Int. Genet., 1, 100, 10.1016/j.fsigen.2007.02.009

Li, 2008, Worldwide human relationships inferred from genome-wide patterns of variation, Science, 319, 1100, 10.1126/science.1153717

Jakobsson, 2008, Genotype, haplotype and copy-number variation in worldwide human populations, Nature, 451, 998, 10.1038/nature06742

Lao, 2006, Proportioning whole-genome single-nucleotide-polymorphism diversity for the identification of geographic population structure and genetic ancestry, Am. J. Hum. Genet., 78, 680, 10.1086/501531

Kersbergen, 2009, Developing a set of ancestry-sensitive DNA markers reflecting continental origins of humans, BMC Genet., 10, 69, 10.1186/1471-2156-10-69

Phillips, 2007, Inferring ancestral origin using a single multiplex assay of ancestry-informative marker SNPs, Forensic Sci. Int. Genet., 1, 273, 10.1016/j.fsigen.2007.06.008

Corach, 2010, Inferring continental ancestry of Argentineans from autosomal, Y-chromosomal and mitochondrial DNA, Ann. Hum. Genet., 74, 65, 10.1111/j.1469-1809.2009.00556.x