Ionic Liquid as an Efficient Promoting Medium for Synthesis of Bis‐Pyrazolo[3,4‐b:4′,3′‐e]Pyridines

Journal of the Chinese Chemical Society - Tập 55 Số 4 - Trang 755-760 - 2008
Daqing Shi1,2,3, Fang Yang2
1College of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University, Suzhou 215123, P. R. China
2College of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou 221116, P. R. China
3Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, Xuzhou 221116, P. R. China

Tóm tắt

AbstractThe preparation of a series of bis‐pyrazolo[3,4‐b:4′,3′‐e]pyridines by the reaction of 5‐aminopyrazole with aldehydes in ionic liquid [bmim]Br is described. This new method has the advantages of easier work‐up, milder reaction conditions, high yields and environmental friendliness compared with other methods.

Từ khóa


Tài liệu tham khảo

10.1016/S1381-1169(01)00465-4

10.1002/aoc.337

10.1002/anie.200390070

10.1002/(SICI)1097-4660(199704)68:4<351::AID-JCTB613>3.0.CO;2-4

10.1039/b110838g

10.1016/S0920-5861(01)00541-7

10.1021/cr980032t

Gordon K. R., 2000, Pure Appl. Chem., 72, 1391, 10.1351/pac200072071391

10.1021/cr010338r

Adams C. J.;Earle M. J.;Roberts G.;Seddon K. R.Chem. Commun.1998 2097.

Stark A.;Maclean B. L.;Singer R. D.J. Chem. Soc. Dalton Trans.1999 63.

10.1016/S0040-4039(98)02415-0

10.1016/S0040-4039(99)00249-X

10.1016/S0040-4039(01)00064-8

10.1021/ol9907771

10.1016/S0040-4039(00)01592-6

10.1016/S0040-4039(01)02041-X

10.1016/S0040-4039(01)01139-X

10.1016/S0040-4039(01)01850-0

10.1016/S0040-4039(00)01974-2

10.1002/1521-3773(20001103)39:21<3772::AID-ANIE3772>3.0.CO;2-5

Sheldon R.Chem. Commun.2001 2399.

10.1002/jccs.200700021

10.1002/jccs.200600114

10.1039/a706561b

Brack A.Dipirazolopyridine. Belg. Patent.1961 616 472;

1962, Chem. Abstr., 58, 73360

10.1016/S0166-1280(97)00181-4

Rechthaler K., 1999, Acta Physica Polonica A., 95, 321, 10.12693/APhysPolA.95.321

10.1021/cm020284h

10.1063/1.1528736

10.1063/1.1425454

10.1002/anie.197406041

10.1016/S0960-894X(98)00372-2

Eid A. I., 1978, J. Pharm. Belg., 33, 303

10.1021/jm960803q

Habib N. S., 1981, Sci. Pharm., 49, 42

10.1016/S0223-5234(98)80004-4

El‐Emary T. I., 1999, Pharmazie, 54, 106

Pathak R. B., 1980, J. Indian Chem. Soc., 57, 1108

Devi S., 1983, J. Indian Chem. Soc., 60, 679

10.1021/jf0202436

10.1016/S1087-1845(02)00003-8

10.1002/jlac.19656810117

10.1016/0040-4020(78)80141-0

Puchala A., 1997, OPPI Briefs., 29, 226

Joshi K. C., 1981, Pharmazie., 36, 336

10.1002/jhet.5570420108

10.1002/prac.19903320312

10.1080/00304949709355191