Ion-induced release of calcium from isolated sarcoplasmic reticulum

The Journal of Membrane Biology - Tập 58 - Trang 21-33 - 1981
Anthony H. Caswell1, Neil R. Brandt1
1Department of Pharmacology, University of Miami School of Medicine, Miami

Tóm tắt

Choline Cl addition to either longitudinal reticulum or terminal cisternae of skeletal muscle sarcoplasmic reticulum caused release of Ca2+ which had previously accumulated in the presence of ATP. However the extent of release was considerably greater in terminal cisternae. Ca2+ accumulation and release by terminal cisternae were also observed using chlorotetracycline as a probe for membrane-associated Ca2+. Among a number of salts and ions tested for effectiveness in causing Ca2+ release the order was gluconate−

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