Iodine Catalyzed Three‐component Strecker‐type Synthesis of α‐Aminonitriles from Aldehydes, Amines and Tributyltin Cyanide

Chinese Journal of Chemistry - Tập 24 Số 1 - Trang 135-137 - 2006
Hongshe Wang1,2,3, Lifang Zhao1, Zhiming Du3
1Department of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, Shaanxi 721007, China
2Project supported by the Special Scientific Research Project of Shaanxi Education Commission (No. 02JK054).
3School of Mechatronic Engineering, Beijing Institute of Technology, Beijing 100081, China

Tóm tắt

Abstract

A simple and efficient one‐pot method has been developed for the synthesis of α‐aminonitriles from aldehydes, amines and tributyltin cyanide in the presence of a catalytic amount of iodine with high yields. The reactions proceeded smoothly at room temperature via very simple procedure.

Từ khóa


Tài liệu tham khảo

10.1016/S0040-4020(01)80840-1

10.1021/jo01284a040

10.1021/jm00266a008

10.1002/(SICI)1521-3773(20000502)39:9<1650::AID-ANIE1650>3.0.CO;2-P

10.1021/ja994121e

10.1081/SCC-120012986

10.1021/ja034980

10.1016/j.tetlet.2004.08.071

10.1081/SCC-120030307

10.1039/B406114B

10.1016/j.tetasy.2004.03.040

10.1039/a801464g

10.1002/(SICI)1521-3773(19981204)37:22<3186::AID-ANIE3186>3.0.CO;2-E

10.1021/ja9935207

10.1081/SCC-120028638

10.1016/j.tetlet.2004.10.021

10.1016/j.tetlet.2004.04.076

10.1016/j.tetlet.2004.08.044

10.1081/SCC-120030695

10.1021/jo0498462

10.1081/SCC-120038496