Involvement of Notch Signaling in Wound Healing

A Apelqvist, 1999, Notch signaling controls pancreatic cell differentiation., Nature, 400, 877, 10.1038/23716

S Artavanis-Tsakonas, 1995, Notch signaling., Science, 268, 225, 10.1126/science.7716513

T Iso, 2003, Notch signaling in vascular development., Arterioscler Thromb Vasc Biol, 23, 543, 10.1161/01.ATV.0000060892.81529.8F

S Shi, 2006, Evolutionary origins of Notch signaling in early development., Cell cycle, 5, 274, 10.4161/cc.5.3.2396

B De Strooper, 1999, A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain., Nature, 398, 518, 10.1038/19083

H Kared, 2006, Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling., Immunity, 25, 823, 10.1016/j.immuni.2006.09.008

Y Wang, 2004, Involvement of Notch signaling in hippocampal synaptic plasticity., Proc Natl Acad Sci USA, 101, 9458, 10.1073/pnas.0308126101

TV Arumugam, 2006, Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke., Nat Med, 12, 621, 10.1038/nm1403

FP Limbourg, 2005, Essential role of endothelial Notch1 in angiogenesis., Circulation, 111, 1826, 10.1161/01.CIR.0000160870.93058.DD

LT Krebs, 2000, Notch signaling is essential for vascular morphogenesis in mice., Genes Dev, 14, 1343, 10.1101/gad.14.11.1343

Y Xue, 1999, Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1., Hum Mol Genet, 8, 723, 10.1093/hmg/8.5.723

T Oda, 1997, Nat Genet, Nat Genet, 16, 235

RC Sainson, 2005, Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis., FASEB J, 19, 1027, 10.1096/fj.04-3172fje

K Takeshita, 2007, Critical role of endothelial Notch1 signaling in postnatal angiogenesis., Circ Res, 100, 70, 10.1161/01.RES.0000254788.47304.6e

D Paris, 2005, Inhibition of angiogenesis and tumor growth by beta and gamma-secretase inhibitors., Eur J Pharmacol, 514, 1, 10.1016/j.ejphar.2005.02.050

M Nakajima, 2003, Abnormal blood vessel development in mice lacking presenilin-1., Mech Dev, 120, 657, 10.1016/S0925-4773(03)00064-9

TK Hunt, 2000, Physiology of wound healing., Adv Skin Wound Care, 13, 6

V Lindner, 2001, Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction., Am J Pathol, 159, 875, 10.1016/S0002-9440(10)61763-4

AB Zimrin, 1996, An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitro., J Biol Chem, 271, 32499, 10.1074/jbc.271.51.32499

H Uyttendaele, 2000, Notch4 and Jagged-1 induce microvessel differentiation of rat brain endothelial cells., Microvasc Res, 60, 91, 10.1006/mvre.2000.2254

A Rangarajan, 2001, Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation., EMBO J, 20, 3427, 10.1093/emboj/20.13.3427

M Dorsch, 2002, Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease., Blood, 100, 2046, 10.1182/blood.V100.6.2046

NJ Savill, 2003, Control of epidermal stem cell clusters by Notch-mediated lateral induction., Dev Biol, 258, 141, 10.1016/S0012-1606(03)00107-6

BJ Nickoloff, 2002, Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma., Cell Death Differ, 9, 842, 10.1038/sj.cdd.4401036

A Cereseto, 2000, Jagged2 induces cell cycling in confluent fibroblasts susceptible to density-dependent inhibition of cell division., J Cell Physiol, 185, 425, 10.1002/1097-4652(200012)185:3<425::AID-JCP13>3.0.CO;2-U

LM Minter, 2005, Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21., Nat.Immunol, 6, 680, 10.1038/ni1209

T Palaga, 2003, TCR-mediated notch signaling regulates proliferation and IFN-gamma production in peripheral T cells., J.Immunol, 171, 3019, 10.4049/jimmunol.171.6.3019

A Androutsellis-Theotokis, 2006, Notch signalling regulates stem cell numbers in vitro and in vivo., Nature, 442, 823, 10.1038/nature04940

J Li, 2003, Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix., Microsc Res Tech, 60, 107, 10.1002/jemt.10249

RK Carmeliet P Jain, 2000, Angiogenesis in cancer and other diseases., Nature, 407, 249, 10.1038/35025220

W Risau, 1997, Mechanisms of angiogenesis., Nature, 386, 671, 10.1038/386671a0

GD Yancopoulos, 1998, Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border., Cell, 93, 661, 10.1016/S0092-8674(00)81426-9

I Noguera-Troise, 2006, Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis., Nature, 444, 1032, 10.1038/nature05355

J Ridgway, 2006, Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis., Nature, 444, 1083, 10.1038/nature05313

Y Zheng, 2006, Chimeric VEGF-ENZ7/PlGF specifically binding to VEGFR-2 accelerates skin wound healing via enhancement of neovascularization., Arterioscler Thromb Vasc Biol, 27, 503, 10.1161/01.ATV.0000256459.06671.3c

P Martin, 1997, Wound healing–aiming for perfect skin regeneration., Science, 276, 75, 10.1126/science.276.5309.75

P Martin, 2005, Inflammatory cells during wound repair: the good, the bad and the ugly., Trends Cell Biol, 15, 599, 10.1016/j.tcb.2005.09.002

E Monsalve, 2006, Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity., J Immunol, 176, 5362, 10.4049/jimmunol.176.9.5362

M Ostroukhova, 2006, Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta., J Clin Invest, 116, 996, 10.1172/JCI26490

EM Six, 2004, The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration., J Biol Chem, 279, 55818, 10.1074/jbc.M408022200

R Okuyama, 2004, High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism., Dev Cell, 6, 551, 10.1016/S1534-5807(04)00098-X

S Aho, 2004, Soluble form of Jagged1: unique product of epithelial keratinocytes and a regulator of keratinocyte differentiation., J Cell Biochem, 92, 1271, 10.1002/jcb.20125

P Cheng, 2001, Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells., J Immunol, 167, 4458, 10.4049/jimmunol.167.8.4458

HF Dovey, 2001, Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain., J Neurochem, 76, 173, 10.1046/j.1471-4159.2001.00012.x

V Sarma, 1992, Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro., J Immunol, 148, 3302, 10.4049/jimmunol.148.10.3302