Inverse agonist activity of agouti and agouti-related protein
Tài liệu tham khảo
Argiolas, 2000, ACTH- and alpha-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors, Brain Res. Bull., 51, 425, 10.1016/S0361-9230(99)00270-1
Barovsky, 1985, Forskolin potentiation of cholera toxin-stimulated cyclic AMP accumulation in intact C6-2B cells. Evidence for enhanced Gs-C coupling, Mol. Pharmacol., 28, 502
Blanchard, 1995, Agouti antagonism of melanocortin binding and action in the B16F10 murine melanoma cell line, Biochemistry, 35, 10406, 10.1021/bi00033a012
Bourne HR, Roberts JM. Drug receptors and pharmacodynamics. In: Katzung BG, editor. Basic and clinical pharmacology. Connecticut: Appleton and Lange; 1992. p. 10–34.
Daeffler, 1999, Inverse agonist activity of pirenzepine at M2 muscarinic acetylcholine receptors, Br. J. Pharmacol., 126, 1246, 10.1038/sj.bjp.0702407
DeBlasi, 1998, Calculating receptor number from binding experiments using same compound as radioligand and competitor, Trends Pharmacol. Sci., 10, 227, 10.1016/0165-6147(89)90266-6
Dinulescu, 2000, Agouti and agouti-related protein: analogies and contrasts, J. Biol. Chem., 275, 6695, 10.1074/jbc.275.10.6695
Fong, 1997, ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors, Biochem. Biophys. Res. Commun., 237, 629, 10.1006/bbrc.1997.7200
Gunn, 1999, The mouse mahogany locus encodes a transmembrane form of human attractin, Nature, 398, 152, 10.1038/18217
Haskell-Luevano, 2001, Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor, Regul. Pept., 99, 1, 10.1016/S0167-0115(01)00234-8
He, 2001, A biochemical function for attractin in agouti-induced pigmentation and obesity, Nat. Genet., 27, 40, 10.1038/83741
Jackson, 2002, Design, pharmacology and NMR structure of a minimized cystine knot with agouti-related protein activity, Biochemistry, 41, 7565, 10.1021/bi012000x
Kask, 1999, Long-term administration of MC4 receptor antagonist HS014 causes hyperphagia and obesity in rats, Neuroreport, 10, 707, 10.1097/00001756-199903170-00009
Kenakin, 2001, Inverse, protean, and ligand-selective agonism: matters of receptor conformation, FASEB J., 15, 598, 10.1096/fj.00-0438rev
Kiefer, 1998, Melanocortin receptor binding determinants in the agouti protein, Biochemistry, 37, 991, 10.1021/bi971913h
Leff, 1995, The two-state model of receptor activation, Trends Pharmacol. Sci., 16, 89, 10.1016/S0165-6147(00)88989-0
Lu, 1994, Agouti protein is an antagonist of the melanocyte-stimulating hormone receptor, Nature, 371, 799, 10.1038/371799a0
McNulty, 2001, High-resolution NMR structure of the chemically-synthesized melanocortin receptor binding domain AGRP(87–132) of the agouti-related protein, Biochemistry, 40, 15520, 10.1021/bi0117192
Norton, 1998, The cystine knot structure of ion channel toxins and related polypeptides, Toxicon, 36, 1573, 10.1016/S0041-0101(98)00149-4
Ollmann, 1997, Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein, Science, 278, 135, 10.1126/science.278.5335.135
Reizes, 2001, Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3, Cell, 106, 105, 10.1016/S0092-8674(01)00415-9
Schioth, 1999, Further pharmacological characterization of the selective melanocortin 4 receptor antagonist HS014: comparison with SHU9119, Neuropeptides, 33, 191, 10.1054/npep.1999.0760
Shutter, 1997, Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated on obese and diabetic mutant mice, Genes Dev., 11, 593, 10.1101/gad.11.5.593
Siegrist, 1997, Interactions of α-melanotropin and agouti on B16 melanoma cells: evidence for inverse agonism of agouti, J. Recept. Signal Transduct. Res., 17, 75, 10.3109/10799899709036595
Tota, 1999, Molecular interaction of agouti protein and agouti-related protein with human melanocortin receptors, Biochemistry, 38, 897, 10.1021/bi9815602
Wouter, 2001, AgRP (83–132) acts as an inverse agonist on the human melanocortin-4 receptor, Mol. Endocrinol., 15, 164, 10.1210/me.15.1.164
Yang, 2001, Functional properties of a chemically synthesized agouti signaling protein variant and binding characteristics of its cognate radioligand, Am. J. Physiol., 281, R1877
Yang, 1997, Effects of recombinant agouti-signaling protein on melanocortin action, Mol. Endocrinol., 11, 274, 10.1210/me.11.3.274
Yang, 1999, Characterization of agouti-related protein binding to melanocortin receptors, Mol. Endocrinol., 13, 148, 10.1210/me.13.1.148