Intravesical ALT-803 for BCG-unresponsive Bladder Cancer – A Case Report

Urology Case Reports - Tập 14 - Trang 15-17 - 2017
Jeffrey Huang1, John Schisler2, Hing C. Wong3, Charles J. Rosser1, Joseph Sterbis2
1University of Hawaii Cancer Center, Clinical & Translational Research Program, Honolulu, HI, 96813, USA
2Tripler Army Medical Center, Department of Urology, Honolulu, HI, 96859, USA
3Altor BioScience Corporation, 2810 North Commerce Parkway, Miramar, FL 33025, USA

Tài liệu tham khảo

Sylvester, 2011, Bacillus Calmette-Guerin treatment of non-muscle invasive bladder cancer, Int J Urol, 18, 113, 10.1111/j.1442-2042.2010.02678.x Herr, 2000, Tumor progression and survival of patients with high grade, noninvasive papillary (TaG3) bladder tumors: 15-year outcome, J Urol, 163, 60 Montecino-Rodriguez, 2013, Causes, consequences, and reversal of immune system aging, J Clin Invest, 123, 958, 10.1172/JCI64096 Gomes-Giacoia, 2014, Intravesical ALT-803 and BCG treatment reduces tumor burden in a carcinogen induced bladder cancer rat model; a role for cytokine production and NK cell expansion, PLoS One, 9, e96705, 10.1371/journal.pone.0096705 Waldmann, 2006, The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design, Nat Rev Immunol, 6, 595, 10.1038/nri1901 Rhode, 2016, Comparison of the superagonist complex, ALT-803, to IL15 as cancer immunotherapeutics in animal models, Cancer Immunol Res, 4, 49, 10.1158/2326-6066.CIR-15-0093-T