Intravenous infusion of mesenchymal stem cells for refractory systemic sclerosis management: Two-year follow-up

Allanore, 2015, Systemic sclerosis, Nat Rev Dis Primers, 1, 15002, 10.1038/nrdp.2015.2 Broen, 2012, Genetics of systemic sclerosis: an update, Curr Rheumatol Rep, 14, 11, 10.1007/s11926-011-0221-7 Katsumoto, 2011, The pathogenesis of systemic sclerosis, Annu Rev Pathol, 6, 509, 10.1146/annurev-pathol-011110-130312 Barnes, 2012, Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers, Curr Opin Rheumatol, 24, 165, 10.1097/BOR.0b013e32834ff2e8 Hao, 2017, Early mortality in a multinational systemic sclerosis inception cohort, Arthritis Rheumatol, 69, 1067, 10.1002/art.40027 Royle, 2018, The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink, Clin Rheumatol, 37, 2103, 10.1007/s10067-018-4182-3 Rubio-Rivas, 2015, Mortality and survival in systemic sclerosis: systematic review and meta-analysis, Semin Arthritis Rheum, 44, 208, 10.1016/j.semarthrit.2014.05.010 LeRoy, 1988, Scleroderma (systemic sclerosis): classification, subsets and pathogenesis, J Rheumatol, 15, 202 Steen, 2005, Autoantibodies in systemic sclerosis, Semin Arthritis Rheum, 35, 35, 10.1016/j.semarthrit.2005.03.005 McNearney, 2007, Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors, Arthritis Rheum, 57, 318, 10.1002/art.22532 Morales-Cardenas, 2016, Pulmonary involvement in systemic sclerosis, Autoimmun Rev, 15, 1094, 10.1016/j.autrev.2016.07.025 Almeida, 2015, Quality of life in systemic sclerosis, Autoimmun Rev, 14, 1087, 10.1016/j.autrev.2015.07.012 Fischer, 2017, Humanistic and cost burden of systemic sclerosis: a review of the literature, Autoimmun Rev, 16, 1147, 10.1016/j.autrev.2017.09.010 Kowal-Bielecka, 2017, Update of EULAR recommendations for the treatment of systemic sclerosis, Ann Rheum Dis, 76, 1327, 10.1136/annrheumdis-2016-209909 Reyes, 2009, Autotransplante exitoso de células madres hematopoyéticas en una mujer con esclerosis sistémica severa refractaria al manejo inmunosupresor, Rev Colomb Reumatol, 16, 375 Chengappa, 2017, Hematopoietic stem cell transplantation in systemic sclerosis, Indian J Rheumatol, 12, 218 Nash, 2007, High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study, Blood, 110, 1388, 10.1182/blood-2007-02-072389 Crisan, 2008, A perivascular origin for mesenchymal stem cells in multiple human organs, Cell Stem Cell, 3, 301, 10.1016/j.stem.2008.07.003 Tyndall, 2016, Stem cell transplantation and mesenchymal cells to treat autoimmune diseases, Presse Med, 45, e159, 10.1016/j.lpm.2016.05.002 Wehbe, 2016, Mesenchymal stem cell therapy for refractory scleroderma: a report of 2 cases, Stem Cell Investig, 3, 48, 10.21037/sci.2016.09.03 Rawat, 2019, Mesenchymal stem cells modulate the immune system in developing therapeutic interventions Peltzer, 2018, Mesenchymal stromal cells based therapy in systemic sclerosis: rational and challenges, Front Immunol, 9, 10.3389/fimmu.2018.02013 Duijvestein, 2010, Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study, Gut, 59, 1662, 10.1136/gut.2010.215152 Sun, 2010, Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus, Arthritis Rheum, 62, 2467, 10.1002/art.27548 Liang, 2012, Allogeneic mesenchymal stem cells transplantation in patients with refractory RA, Clinical Rheumatol, 31, 157, 10.1007/s10067-011-1816-0 Liang, 2020, Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells: a case report, Medicine (Baltimore), 99, e21429, 10.1097/MD.0000000000021429 Leng, 2020, Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia, Aging Dis, 11, 216, 10.14336/AD.2020.0228 Cras, 2015, Update on mesenchymal stem cell-based therapy in lupus and scleroderma, Arthritis Res Ther, 17, 301, 10.1186/s13075-015-0819-7 McKenna, 2006, The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR): a measure of health-related quality of life and quality of life for patients with pulmonary hypertension, Qual Life Res, 15, 103, 10.1007/s11136-005-3513-4 Sullivan, 2012, Haemopoietic stem-cell transplantation for systemic sclerosis, Lancet, 379, 219, 10.1016/S0140-6736(12)60100-7 Christopeit, 2008, Marked improvement of severe progressive systemic sclerosis after transplantation of mesenchymal stem cells from an allogeneic haploidentical-related donor mediated by ligation of CD137L, Leukemia, 22, 1062, 10.1038/sj.leu.2404996 Guiducci, 2010, Autologous mesenchymal stem cells foster revascularization of ischemic limbs in systemic sclerosis: a case report, Ann Intern Med, 153, 650, 10.7326/0003-4819-153-10-201011160-00007 Lalu, 2012, Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials, PLoS One, 7, e47559, 10.1371/journal.pone.0047559 Chakr, 2013, AB0505 Case report of allogeneic unrelated-donor mesenchymal stem cells (msc) infusion in systemic sclerosis (ssc), Ann Rheum Dis, 72, A943, 10.1136/annrheumdis-2013-eular.2827 Zandman-Goddard, 2005, New therapeutic strategies for systemic sclerosis--a critical analysis of the literature, Clin Dev Immunol, 12, 165, 10.1080/17402520500233437 Sullivan, 2018, Myeloablative autologous stem-cell transplantation for severe scleroderma, N Engl J Med, 378, 35, 10.1056/NEJMoa1703327