Intravenous amiodarone modifies autonomic balance and increases baroreflex sensitivity in conscious rats

Autonomic Neuroscience - Tập 95 - Trang 88-96 - 2002
Valdo José Dias da Silva1,2, Públio Cesar Cavalcante Viana1, Rodrigo de Melo Alves1, Rubens Fazan1, Tomaso Gnecchi Ruscone2, Alberto Porta2, Alberto Malliani2, Helio Cesar Salgado3, Nicola Montano2
1Department of Biological Sciences, School of Medicine of Triangulo Mineiro, Uberaba (MG), Brazil
2Centro Ricerche Cardiovascolari, CNR, Dipartimento di Scienze Precliniche (DiSP), LITA di Vialba, Medicina Interna II, Ospedale L. Sacco, Universita' degli Studi di Milano, via GB Grassi, 74 20157 Milan, Italy
3Department of Physiology, School of Medicine of Ribeirao Preto, USP, Ribeirao Preto (SP), Brazil

Tài liệu tham khảo

Akselrod, 1981, Power spectrum analysis of heart fluctuation: a quantitative probe of beat-to-beat cardiovascular control, Science, 213, 220, 10.1126/science.6166045 Bacq, 1976, The effects of amiodarone, an alpha and beta receptor antagonist, on adrenergic transmission in the cat spleen, Biochem. Pharmacol., 25, 1195, 10.1016/0006-2952(76)90368-3 Baselli, 1986, Spectral and cross-spectral analysis of heart rate and arterial blood pressure variability signals, Comp. Biomed. Res., 19, 520, 10.1016/0010-4809(86)90026-1 Butcher, 1998, K+ channel blockade in the NTS alters efficacy of two cardiorespiratory reflexes in vivo, Am. J. Physiol., 274, R677 Chevalier, 1995, Trandolapril decreases prevalence of ventricular ectopic activity in middle-aged SHR, Circulation, 92, 1947, 10.1161/01.CIR.92.7.1947 Cohen-Armon, 1984, Interaction of the antiarrhythmic drug amiodarone with the muscarinic receptor in rat heart and brain, J. Cardiovasc. Pharmacol., 6, 1148, 10.1097/00005344-198411000-00023 Connolly, 1999, Evidence-based analysis of amiodarone efficacy and safety, Circulation, 100, 2025, 10.1161/01.CIR.100.19.2025 Da Silva, 2000, Intravenous amiodarone reduces cervical pre-ganglionic sympathetic discharge in decerebrate rats, Circulation, 102, 2506 Du, 1995, Sympatholytic action of intravenous amiodarone in the rat heart, Circulation, 91, 462, 10.1161/01.CIR.91.2.462 Gloor, 1983, Acute effects of amiodarone upon the canine sinus node and atrioventricular junctional region, J. Clin. Invest., 71, 1457, 10.1172/JCI110899 Gough, 1982, Hypotensive action of commercial intravenous amiodarone and polysorbate 80 in dogs, J. Cardiovasc. Pharmacol., 4, 375, 10.1097/00005344-198205000-00006 Gray, 1998, Amiodarone inhibits the Na+–K+ pump in rabbit cardiac myocytes after acute and chronic treatment, J. Pharmacol. Exp. Ther., 284, 75 Hoffmeister, 1997, Hemodynamic effects of antiarrhythmic compounds: intrinsic effects and autonomic modulation, Am. J. Cardiol., 80, 24G, 10.1016/S0002-9149(97)00711-X Judy, 1976, Sympathetic nerve activity: role in regulation of blood pressure in the spontaneously hypertensive rat, Circ. Res., 38, 21, 10.1161/01.RES.38.6.21 Kamath, 1992, Effect of vagal nerve electric stimulation on the power spectrum on heart rate variability in man, Pacing Clin. Electrophysiol., 15, 235, 10.1111/j.1540-8159.1992.tb03067.x Kodama, 1999, Amiodarone: ionic and cellular mechanisms of action of the most promising class III agent, Am. J. Cardiol., 84, 20R, 10.1016/S0002-9149(99)00698-0 Kowey, 1995, Randomized, double-blind comparison of intravenous amiodarone and bretylium in the treatment of patients with recurrent, hemodynamically destabilizing ventricular tachycardia or fibrillation, Circulation, 92, 3255, 10.1161/01.CIR.92.11.3255 Kowey, 1997, Intravenous amiodarone, J. Am. Coll. Cardiol., 29, 1190, 10.1016/S0735-1097(97)00069-7 Kudenchuk, 1999, Amiodarone for resuscitation after out-of-hospital cardiac arrest due to ventricular fibrillation, N. Engl. J. Med., 341, 871, 10.1056/NEJM199909163411203 La Rovere, 1994, Scopolamine improves autonomic balance in advanced congestive heart failure, Circulation, 90, 838, 10.1161/01.CIR.90.2.838 La Rovere, 1998, Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction, Lancet, 351, 478, 10.1016/S0140-6736(97)11144-8 Lazzeri, 1998, Effects of clonidine on power spectral analysis of heart rate variability in mild essential hypertension, J. Auton. Nerv. Syst., 74, 152, 10.1016/S0165-1838(98)00148-9 Lucini, 1994, Sympathetic restraint of baroreflex control of heart period in normotensive and hypertensive subjects, Clin. Sci., 86, 547, 10.1042/cs0860547 Malliani, 1980, Neural mechanisms in life-threatening arrhythmias, Am. Heart J., 200, 705, 10.1016/0002-8703(80)90238-0 Malliani, 1991, Cardiovascular neural regulation explored in the frequency domain, Circulation, 84, 482, 10.1161/01.CIR.84.2.482 Martens, 1998, Ion channels in vascular smooth muscle: alterations in essential hypertension, Proc. Soc. Exp. Biol. Med., 218, 192, 10.3181/00379727-218-44286 Montano, 1998, Central vagotonic effects of atropine modulate spectral oscillations of sympathetic nerve activity, Circulation, 98, 1394, 10.1161/01.CIR.98.14.1394 Murthy, 1986, Antiarrhythmic drugs and modulation of autonomic control of heart rate in rabbits, Fed. Proc., 45, 2186 Nattel, 1999, Evolution, mechanisms, and classification of antiarrhythmic drugs: focus on class III actions, Am. J. Cardiol., 84, 11R, 10.1016/S0002-9149(99)00697-9 Pagani, 1986, Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympathovagal interaction in man and conscious dog, Circ. Res., 59, 178, 10.1161/01.RES.59.2.178 Pagani, 1988, Changes in autonomic regulation induced by physical training in mild hypertension, Hypertension., 12, 600, 10.1161/01.HYP.12.6.600 Podrid, 1990, Role of the sympathetic nervous system in the genesis of ventricular arrhythmias, Circulation, 82, I103 Riva, 1982, Pharmacokinetics of amiodarone in rats, J. Cardiovasc. Pharmacol., 4, 270, 10.1097/00005344-198203000-00016 Rubini, 1993, Power spectrum analysis of cardiovascular variability monitored by telemetry in conscious unrestrained rats, J. Auton. Nerv. Syst., 45, 181, 10.1016/0165-1838(93)90050-5 Schwartz, 1992, Autonomic nervous system and sudden cardiac death: experimental basis and clinical observations for post-myocardial infarction risk stratification, Circulation, 85, I77 1996, Heart rate variability: standards of measurement, physiological interpretation and clinical use, Circulation, 93, 1043, 10.1161/01.CIR.93.5.1043 Watanabe, 1996, Inhibitory effect of amiodarone on muscarinic acetylcholine receptor-operated potassium current in guinea pig atrial cells, J. Pharmacol. Exp. Ther., 279, 617 Weir, 1986, Amiodarone pharmacokinetics: I. Acute dose-dependent disposition studies in rats, J. Pharmacokinet. Biopharm., 14, 601, 10.1007/BF01067966 Widdop, 1990, Impaired arterial baroreceptor reflex and cardiopulmonary vagal reflex in conscious spontaneously hypertensive rats, J. Hypertens., 8, 269, 10.1097/00004872-199003000-00009 Wyss, 1990, Single-dose kinetics of tissue distribution, excretion and metabolism of amiodarone in rats, J. Pharmacol. Exp. Ther., 254, 502