Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

Neurobiology of Disease - Tập 82 - Trang 185-199 - 2015
Katrina L. Paumier1, Kelvin C. Luk2, Fredric P. Manfredsson3, Nicholas M. Kanaan3, Jack W. Lipton3, Timothy J. Collier3, Kathy Steece‐Collier3, Christopher J. Kemp4, Stephanie L. Celano4, Emily Schulz4, Ivette M. Sandoval4, Sheila M. Fleming5, Elliott W. Dirr5, Nicole K. Polinski4, John Q. Trojanowski2, Virginia M. Lee2, Caryl E. Sortwell3
1Department of Translational Science and Molecular Medicine, Michigan State University, Grand Rapids, MI, USA
2Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
3Department of Translational Science and Molecular Medicine, Michigan State University, Grand Rapids, MI, USA; Mercy Health Hauenstein Neuroscience Medical Center, Grand Rapids, MI, USA.
4Department of Translational Science & Molecular Medicine, Michigan State University, Grand Rapids, MI, USA.
5Department of Psychology, University of Cincinnati, Cincinnati, OH USA

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