Intrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during Reprogramming

Cell Stem Cell - Tập 13 - Trang 30-35 - 2013
He Zhang1,2, Weiwei Jiao3,2, Lin Sun3,2, Jiayan Fan1,2, Mengfei Chen4, Hong Wang5, Xiaoyi Xu5, Adong Shen3, Tao Li4, Beibei Niu2, Shengfang Ge1, Wei Li5, Jiuwei Cui5, Guanjun Wang5, Jingnan Sun5, Xianqun Fan1, Xiang Hu4, Randall J. Mrsny6,7, Andrew R. Hoffman2, Ji-Fan Hu5,2,6
1Department of Ophthalmology, Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200025, P.R. China
2VA Palo Alto Health Care System, Stanford University Medical School, Palo Alto, CA 94304, USA
3Beijing Pediatric Institute, Beijing Children’s Hospital affiliated with Capital Medical University, Beijing 100045, P.R. China
4Shenzhen Beike Cell Engineering Research Institute, Shenzhen 518057, P.R. China
5Stem Cell and Cancer Center, First Affiliated Hospital, Jilin University, Changchun 130021, P.R. China
6GMR Epigenetics, Palo Alto, CA 94303, USA
7Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK

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