Intracellular protein delivery with a dimerizable amphiphile for improved complex stability and prolonged protein release in the cytoplasm of adherent cell lines

Zelphati, 2001, Intracellular delivery of proteins with a new lipid-mediated delivery system, J. Biol. Chem., 276, 35103, 10.1074/jbc.M104920200 Gros, 2006, A non-covalent peptide-based strategy for protein and peptide nucleic acid transduction, Biochim. Biophys. Acta, 1758, 384, 10.1016/j.bbamem.2006.02.006 Dalkara, 2004, Intracytoplasmic delivery of anionic proteins, Molec. Ther., 9, 964, 10.1016/j.ymthe.2004.03.007 Merdan, 2002, Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments, Pharm. Res., 140, 10.1023/A:1014212630566 Bausinger, 2006, The transport of nanosized gene carriers unraveled by live-cell imaging, Angew. Chem., Int. Ed. Engl., 45, 1568, 10.1002/anie.200503021 Mislick, 1996, Evidence for the role of proteoglycans in cation-mediated gene transfer, Proc. Natl. Acad. Sci. U. S. A., 93, 12349, 10.1073/pnas.93.22.12349 Kopatz, 2004, A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin, J. Gene Med., 6, 769, 10.1002/jgm.558 Ajmani, 1999, 3Beta [N-(N′,N′-dimethylaminoethane)-carbamoyl] cholesterol (DC-Chol)-mediated gene delivery to primary rat neurons: characterization and mechanism, Neurochem. Res., 24, 699, 10.1023/A:1021012727796 Tang, 1999, Use of dithiodiglycolic acid as a tether for cationic lipids decreases the cytotoxicity and increases transgene expression of plasmid DNA in vitro, Bioconjug. Chem., 10, 791, 10.1021/bc990016i Lynn, 2001, Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library, J. Am. Chem. Soc., 123, 8155, 10.1021/ja016288p Goula, 1998, Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system, Gene Ther., 712, 10.1038/sj.gt.3300635 Ogris, 1998, The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells, Gene Ther., 5, 1425, 10.1038/sj.gt.3300745 Pons, 2006, Omega-hydrazino linear polyethylenimine: a monoconjugation building block for nucleic acid delivery, ChemBioChem, 7, 303, 10.1002/cbic.200500349 Shuai, 2005, Supramolecular gene delivery vectors showing enhanced transgene expression and good biocompatibility, Bioconjug. Chem., 16, 322, 10.1021/bc0498471 Crotts, 1998, Protein delivery from poly(lactic-co-glycolic acid) biodegradable microspheres: release kinetics and stability issues, J. Microencapsul, 15, 699, 10.3109/02652049809008253 Rojas, 1999, Optimization of the encapsulation and release of beta-lactoglobulin entrapped poly(dl-lactide-co-glycolide) microspheres, Int. J. Pharm., 183, 67, 10.1016/S0378-5173(99)00046-0 Zhu, 2000, Stabilization of proteins encapsulated in injectable poly (lactide-co-glycolide), Nat. Biotechnol., 18, 52, 10.1038/71916 Yu, 2005, The specific delivery of proteins to human liver cells by engineered bio-nanocapsules, FEBS J., 272, 3651, 10.1111/j.1742-4658.2005.04790.x Blessing, 2000, Dimerizable detergents as gene transfer vectors, J. Liposome Res., 10, 321, 10.3109/08982100009031102 Chittimalla, 2005, Monomolecular DNA nanoparticles for intravenous delivery of genes, J. Am. Chem. Soc., 127, 11436, 10.1021/ja0522332 Zuber, 2005, Targeted gene delivery to cancer cells with nanometric DNA particles enveloped with folic acid using a polymerisable anchor, Technol. Cancer Res. Treatment, 4, 637, 10.1177/153303460500400607 Dauty, 2001, Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture, J. Am. Chem. Soc., 123, 9227, 10.1021/ja015867r Zuber, 2000, Assembly of retrovirus capsid-nucleocapsid proteins in the presence of membranes or RNA, J. Virol., 74, 7431, 10.1128/JVI.74.16.7431-7441.2000 Riddles, 1979, Ellman's reagent: 5,5′-dithiobis(2-nitrobenzoic acid)—a reexamination, Anal. Biochem., 94, 75, 10.1016/0003-2697(79)90792-9 Fisher, 1980, Three-dimensional structures of C-phycocyanin and B-phycoerythrin at 5-A resolution, J. Biol. Chem., 255, 5082, 10.1016/S0021-9258(19)70752-2 Glazer, 1979, Characterization of cyanobacterial phycobilisomes in zwitterionic detergents, Proc. Natl. Acad. Sci. U. S. A., 76, 6162, 10.1073/pnas.76.12.6162 Spagnou, 2004, Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA, Biochemistry, 43, 13348, 10.1021/bi048950a Goulian, 2000, Tracking single proteins within cells, Biophys. J., 79, 2188, 10.1016/S0006-3495(00)76467-8