Intracellular distribution and internalization pathways of guanidinylated bioresponsive poly(amido amine)s in gene delivery

Asian Journal of Pharmaceutical Sciences - Tập 13 - Trang 360-372 - 2018
Jinmin Zhang1, Chunxi Wang1, Mei Lu1, Haonan Xing1, Tianzhi Yang2, Cuifang Cai1, Xiaoyun Zhao3, Minjie Wei4, Jiankun Yu5, Pingtian Ding1
1School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
2Department of Basic Pharmaceutical Sciences, School of Pharmacy, Husson University, Bangor, ME, 04401, USA
3Department of Microbiology and Cell Biology, School of life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, 110016, China
4Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang 110122, China
5Department of Ion Channel Pharmacology, School of Pharmacy, China Medical University, Shenyang 110122, China

Tài liệu tham khảo

Thomas, 2003, Progress and problems with the use of viral vectors for gene therapy, Nat Rev Genet, 4, 346, 10.1038/nrg1066 Baum, 2006, Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors, Hum Gene Ther, 17, 253, 10.1089/hum.2006.17.253 Singer, 2008, Applications of lentiviral vectors for shRNA delivery and transgenesis, Curr Gene Ther, 8, 483, 10.2174/156652308786848067 Pedroso de Lima, 2001, Cationic lipid–DNA complexes in gene delivery: from biophysics to biological applications, Adv Drug Deliv Rev, 47, 277, 10.1016/S0169-409X(01)00110-7 Ferruti, 1985, Synthesis, physico-chemical properties and biomedical applications of poly(amido amine)s, Polymer, 26, 1336, 10.1016/0032-3861(85)90309-X Pack, 2005, Design and development of polymers for gene delivery, Nat Rev Drug Discov, 4, 581, 10.1038/nrd1775 Ferruti, 2002, Poly(amido-amine)s: biomedical applications, Macromol Rapid Commun, 23, 332, 10.1002/1521-3927(20020401)23:5/6<332::AID-MARC332>3.0.CO;2-I Meng, 2009, Reduction-sensitive polymers and bioconjugates for biomedical applications, Biomaterials, 30, 2180, 10.1016/j.biomaterials.2009.01.026 Sirri, 2008, Nucleolus: the fascinating nuclear body, Histochem Cell Biol, 129, 13, 10.1007/s00418-007-0359-6 Pyper, 1998, The nucleolus is the site of Borna disease virus RNA transcription and replication, J Virol, 72, 7697, 10.1128/JVI.72.9.7697-7702.1998 Brunner, 2002, Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation, Mol Ther, 5, 80, 10.1006/mthe.2001.0509 Brunner, 2000, Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus, Gene Ther, 7, 401, 10.1038/sj.gt.3301102 Frankel, 1988, Cellular uptake of the tat protein from human immunodeficiency virus, Cell, 55, 1189, 10.1016/0092-8674(88)90263-2 Khalil, 2006, Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery, Pharmacol Rev, 58, 32, 10.1124/pr.58.1.8 Torchilin, 2001, TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors, Proc Natl Acad Sci USA, 98, 8786, 10.1073/pnas.151247498 Wender, 2008, The design of guanidinium-rich transporters and their internalization mechanisms, Adv Drug Deliv Rev, 60, 452, 10.1016/j.addr.2007.10.016 Nimesh, 2008, Guanidinium-grafted polyethylenimine: an efficient transfecting agent for mammalian cells, Eur J Pharm Biopharm, 68, 647, 10.1016/j.ejpb.2007.09.008 Grecco, 2011, Signaling from the living plasma membrane, Cell, 144, 897, 10.1016/j.cell.2011.01.029 Yan, 2012, Engineering particles for therapeutic delivery: prospects and challenges, ACS Nano, 6, 3663, 10.1021/nn3016162 Albanese, 2012, The effect of nanoparticle size, shape, and surface chemistry on biological systems, Annu Rev Biomed Eng, 14, 1, 10.1146/annurev-bioeng-071811-150124 Herd, 2013, Nanoparticle geometry and surface orientation influence mode of cellular uptake, ACS Nano, 7, 1961, 10.1021/nn304439f Kumari, 2010, Endocytosis unplugged: multiple ways to enter the cell, Cell Res, 20, 256, 10.1038/cr.2010.19 Nam, 2009, Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles, J Control Release, 135, 259, 10.1016/j.jconrel.2009.01.018 Wang, 1993, Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation, J Cell Biol, 123, 1107, 10.1083/jcb.123.5.1107 Boussif, 1995, A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine, Proc Natl Acad Sci USA, 92, 7297, 10.1073/pnas.92.16.7297 Conner, 2003, Regulated portals of entry into the cell, Nature, 422, 37, 10.1038/nature01451 Felgner, 1987, Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure, Proc Natl Acad Sci USA, 84, 7413, 10.1073/pnas.84.21.7413 Kim, 2010, A guanidinylated bioreducible polymer with high nuclear localization ability for gene delivery systems, Biomaterials, 31, 1798, 10.1016/j.biomaterials.2009.10.034 Yu, 2016, Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery, Int J Nanomed, 11, 4011, 10.2147/IJN.S115773 Xing, 2016, Molecular weight determination of a newly synthesized guanidinylated disulfide-containing poly(amido amine) by gel permeation chromatography, Asian J Pharm Sci, 12, 292, 10.1016/j.ajps.2016.11.001 Tong, 2016, Serum starvation and thymidine double blocking achieved efficient cell cycle synchronization and altered the expression of p27, p53, bcl-2 in canine breast cancer cells, Res Vet Sci, 105, 10, 10.1016/j.rvsc.2016.01.008 Chang, 2009, Characterization of endocytosis of transferrin-coated PLGA nanoparticles by the blood-brain barrier, Int J Pharm, 379, 285, 10.1016/j.ijpharm.2009.04.035 Swanson, 1995, Macropinocytosis, Trends Cell Biol, 5, 424, 10.1016/S0962-8924(00)89101-1 Vercauteren, 2010, The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls, Mol Ther, 18, 561, 10.1038/mt.2009.281 Zambrano, 2016, Improved preimplantation development of bovine ICSI embryos generated with spermatozoa pretreated with membrane-destabilizing agents lysolecithin and Triton X-100, Theriogenology, 86, 1489, 10.1016/j.theriogenology.2016.05.007 Gerlich, 2003, Global chromosome positions are transmitted through mitosis in mammalian cells, Cell, 112, 751, 10.1016/S0092-8674(03)00189-2 Michihara, 2005, Disruptive effect of chloroquine on lysosomes in cultured rat hepatocytes, Biol Pharm Bull, 28, 947, 10.1248/bpb.28.947 Wattiaux, 2000, Endosomes, lysosomes: their implication in gene transfer, Adv Drug Deliv Rev, 41, 201, 10.1016/S0169-409X(99)00066-6 Liu, 2012, An oligopeptide ligand-mediated therapeutic gene nanocomplex for liver cancer-targeted therapy, Biomaterials, 33, 2240, 10.1016/j.biomaterials.2011.11.082 Dubois, 2015, Cationic poly(amidoamine) promotes cytosolic delivery of bovine RNase A in melanoma cells, while maintaining its cellular toxicity, J Mater Chem B, 3, 6501, 10.1039/C4TB02065K