Intra-arterial thrombolysis using recombinant tissue plasminogen activator (r-TPA): The optimal agent, at the optimal dose?

Dotter, 1974, Selective clot lysis with low-dose streptokinase, Radiology, 111, 31, 10.1148/111.1.31 Hess, 1982, Local low-dose thrombolytic therapy of peripheral arterial occlusions, N Engl Med, 307, 1627, 10.1056/NEJM198212233072606 Earnshaw, 1987, Low dose intra-arterial streptokinase and acylated plasminogen-streptokinase activator complex: a retrospective review of two thrombolytic regimes in recent peripheral arterial ischaemia, Eur J Vasc Surg, 1, 151, 10.1016/S0950-821X(87)80041-5 Astrup, 1966, Tissue activators of plasminogen, 25, 42 Rijken, 1979, Purification and partial characterisation of plasminogen activator from human uterine tissue, Biochem Biophys, 580, 140 Pennica, 1983, Clothing and expression of human tissue-type plasminogen activator cDNA in E. Coli, Nature, 291, 214, 10.1038/301214a0 Collen, 1984, Biological properties of human tissue-type plasminogen activator obtained by expression of recombinant DNA in mammalian cells, J Pharmacol Exp Ther, 23, 146 Holvaert, 1985, Assay of human tissue-type plasminogen activator with an enzyme-linked immunosorbent assay (ELISA) based on three murine monoclonal antibodies to tPA, Thromb Haemostat, 54, 684, 10.1055/s-0038-1660097 Earnshaw, 1987, A dose ranging study of recombinant tissue plasminogen activator in peripheral arterial thrombosis Poliwoda, 1972, Treatment of chronic arterial occlusions with streptokinase, J. Clin Path, 25, 642, 10.1136/jcp.25.7.642 Conard, 1979, Complications hemorragiques an Cours de 98 traitements par la streptokinase, La Nouvelle Prese Medicale, 8, 1319 Becker GJ, Rabe FE, Hogan RD. et al. Thrombolytic agents: Effects of local infusion on microvascular physiology and microvascular ultrastructure. Radiology, 148: 403–406. Mori, 1983, Selective streptokinase infusion: clinical and laboratory correlates, Radiology, 148, 677, 10.1148/radiology.148.3.6878683 Walker, 1985, Low-dose intra-arterial streptokinase: benefit versus risk, Clin Radiol, 36, 345, 10.1016/S0009-9260(85)80297-X Rabe, 1982, Contrast extravasation through dacron grafts: A sequela of low dose streptokinase therapy, A.J.R., 138, 917 Swanson, 1973, Effect of time on vascular prostheses susceptibility to infection of bacteraemic origin, Surg Forum, 24, 28 Plecha, 1985, The early results of vascular surgery in patients over 75 years of age and older, J Vasc Surg, 2, 769, 10.1016/0741-5214(85)90120-X Dale, 1984, Differential management of acute peripheral arterial ischaemia, J Vasc Surg, 1, 269, 10.1067/mva.1984.avs0010269 Dryski, 1984, Acute ischaemia of the extremities in a metropolitan area during one year, J Vasc Surg, 25, 518 Cambria, 1984, Acute arterial thrombosis of the lower extremity, J. Vasc Surg, 1, 269 Collen, 1986, Tissue-type plasminogen activator therapeutic potential in thrombotic disease states, Drugs, 31, 1, 10.2165/00003495-198631010-00001 Mattson, 1983, Dissolution of thrombi by tissue plasminogen activator, urokinase and streptokinase in an Artificial Circulating System, Thromb Res, 21, 535, 10.1016/0049-3848(81)90254-1 Berridge, 1989, Fibrinolytic profiles in local low-dose thrombolysis with streptokinase and recombinant tissue plasminogen activator, Thromb Haemostat Graor, 1986, Thrombolysis with recombinant tissue-type plasminogen activator in patients with peripheral artery and bypass occlusions, Circulation, 74, 15 Graor, 1984, Low-dose streptokinase for selective thrombolysis: Systemic effects and complications, Radiology, 152, 35, 10.1148/radiology.152.1.6729135 Rijken, 1981, Purification and characterisation of the plasminoen activator secreted by human melanoma cells in culture, J Biol Chem, 36, 7035, 10.1016/S0021-9258(19)69095-2 Martin, 1979, Thrombolytic therapy in arterial thromboembolism, Prog Cardiovasc Dis, 11, 351, 10.1016/0033-0620(79)90008-2 Earnshaw, 1986, The systemic fibrinolytic effect of BRL 26921 during the treatment of acute peripheral arterial occlusions, Thromb Haemostat, 55, 259, 10.1055/s-0038-1661532 McPhail, 1983, Management of acute thromboembolic limb ischaemia, Surgery, 93, 381 Katzen, 1984, Low dose direct fibrinolysis in peripheral vascular disease, J Vasc Surg, 718, 10.1016/0741-5214(84)90147-2