International guideline development for the determination of death
Tóm tắt
This report summarizes the results of the first phase in the development of international guidelines for death determination, focusing on the biology of death and the dying process, developed by an invitational forum of international content experts and representatives of a number of professional societies. Precise terminology was developed in order to improve clarity in death discussion and debate. Critical events in the physiological sequences leading to cessation of neurological and/or circulatory function were constructed. It was agreed that death determination is primarily clinical and recommendations for preconditions, confounding factors, minimum clinical standards and additional testing were made. A single operational definition of human death was developed: ‘the permanent loss of capacity for consciousness and all brainstem functions, as a consequence of permanent cessation of circulation or catastrophic brain injury’. In order to complete the project, in the next phase, a broader group of international stakeholders will develop clinical practice guidelines, based on comprehensive reviews and grading of the existing evidence.
Tài liệu tham khảo
Cantarovich F (2005) Public opinion and organ donation suggestions for overcoming barriers. Ann Transplant 10(1):22–25
Joffe AR, Anton NR, deCaen AR (2008) Survey of pediatricians’ opinions on donation after cardiac death: are the donors dead? Pediatrics 122(5):e967–e974
Delmonico FL, Dominguez-Gil B, Matesanz R, Noel L (2011) A call for government accountability to achieve national self-sufficiency in organ donation and transplantation. Lancet 378(9800):1414–1418
Tonelli M, Wiebe N, Knoll G, Bello A, Browne S, Jadhav D et al (2011) Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant 11(10):2093–2109
Alba AC, Alba LF, Delgado DH, Rao V, Ross HJ, Goeree R (2013) Cost-effectiveness of ventricular assist device therapy as a bridge to transplant in comparison to non-bridged cardiac recipients. Circulation 127:2424–2435
Shimazono Y (2007) The state of the international organ trade: a provisional picture based on integration of available information. Bull World Health Organ 85(12):955–962
Branigan T (2009) Executed prisoners are main source of Chinese organ donations. http://www.guardian.co.uk/world/2009/aug/26/china-organ-donation-prisoners. Accessed 3 Jun 2013
(2013) Crisis in Germany’s organ transplantation system. Lancet 381(9862):178
(2008) Organ trafficking and transplant tourism and commercialism: the Declaration of Istanbul. Lancet 372(9632):5–6
(2011) The Madrid resolution on organ donation and transplantation: national responsibility in meeting the needs of patients, guided by the WHO principles. Transplantation 91(Suppl 11):S29–31
WHO (2010) WHO guiding principles on human cell, tissue and organ transplantation (2010) 63rd WHA resolutions and decisions: WHA 63:22. Human organ and tissue transplantation. http://apps.who.int/gb/ebwha/pdf_files/WHA63-REC1/WHA63_REC1-en.pdf. Accessed 21 Jan 2014
Wijdicks EF, Varelas PN, Gronseth GS, Greer DM (2010) Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 74(23):1911–1918
Shemie SD, Doig C, Dickens B, Byrne P, Wheelock B, Rocker G et al (2006) Severe brain injury to neurological determination of death: Canadian forum recommendations. CMAJ 174(6):S1–13
Reich DJ, Mulligan DC, Abt PL, Pruett TL, Abecassis MM, D’Alessandro A et al (2009) ASTS recommended practice guidelines for controlled donation after cardiac death organ procurement and transplantation. Am J Transplant 9(9):2004–2011
Hornby K, Hornby L, Shemie SD (2010) A systematic review of autoresuscitation after cardiac arrest. Crit Care Med 38(5):1246–1253
Wijdicks EF, Diringer MN (2004) Electrocardiographic activity after terminal cardiac arrest in neurocatastrophes. Neurology 62(4):673–674
Sheth KN, Nutter T, Stein DM, Scalea TM, Bernat JL (2012) Autoresuscitation after asystole in patients being considered for organ donation. Crit Care Med 40(1):158–161
Dhanani S, Hornby L, Ward R, Shemie S (2012) Variability in the determination of death after cardiac arrest: a review of guidelines and statements. J Intensive Care Med 27(4):238–252
Moss J, Rockoff M (1980) EEG monitoring during cardiac arrest and resuscitation. JAMA 244(24):2750–2751
Clute HL, Levy WJ (1990) Electroencephalographic changes during brief cardiac arrest in humans. Anesthesiology 73(5):821–825
Losasso TJ, Muzzi DA, Meyer FB, Sharbrough FW (1992) Electroencephalographic monitoring of cerebral function during asystole and successful cardiopulmonary resuscitation. Anesth Analg 75(6):1021–1024
Bernat JL, Capron AM, Bleck TP, Blosser S, Bratton SL, Childress JF et al (2010) The circulatory-respiratory determination of death in organ donation. Crit Care Med 38(3):963–970
