Interleukin-17A

Der Nephrologe - Tập 8 - Trang 255-257 - 2013
A. Brinkhoff1, B. Wilde1,2
1Klinik für Nephrologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Deutschland
2Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University, Maastricht, Niederlande

Tài liệu tham khảo

Maddur MS, Miossec P, Kaveri SV, Bayry J (2012) Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies. Am J Pathol 181:8–18 Miossec P, Kolls JK (2012) Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov 11:763–776 Hsu H-C, Yang P, Wang J et al (2008) Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol 9:166–175 Miossec P, Korn T, Kuchroo VK (2009) Interleukin-17 and type 17 helper T cells. N Engl J Med 361:888–898 Gaffen SL (2009) The role of interleukin-17 in the pathogenesis of rheumatoid arthritis. Curr Rheumatol Rep 11:365–370 Lin AM, Rubin CJ, Khandpur R et al (2011) Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol 187:490–500 Turner JE, Paust HJ, Steinmetz OM, Panzer U (2010) The Th17 immune response in renal inflammation. Kidney Int 77:1070–1075 Kitching AR, Holdsworth SR (2011) The emergence of TH17 cells as effectors of renal injury. J Am Soc Nephrol 22:235–238 Van Kooten C, Boonstra JG, Paape ME et al (1998) Interleukin-17 activates human renal epithelial cells in vitro and is expressed during renal allograft rejection. J Am Soc Nephrol 9:1526–1534 Crispín JC, Oukka M, Bayliss G et al (2008) Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. J Immunol 181:8761–8766 Velden J, Paust H-J, Hoxha E et al (2012) Renal IL-17 expression in human ANCA-associated glomerulonephritis. Am J Physiol Renal Physiol 302:F1663–F1673 Pisitkun P, Ha H-L, Wang H et al (2012) Interleukin-17 cytokines are critical in development of fatal lupus glomerulonephritis. Immunity 37:1104–1115 Zhang Z, Kyttaris VC, Tsokos GC (2009) The role of IL-23/IL-17 axis in lupus nephritis. J Immunol 183:3160–3169 Dolff S, Bijl M, Huitema MG et al (2011) Disturbed Th1, Th2, Th17 and treg balance in patients with systemic lupus erythematosus. Clin Immunol 141:197–204 Yang J, Chu Y, Yang X et al (2009) Th17 and natural treg cell population dynamics in systemic lupus erythematosus. Arthritis Rheum 60:1472–1483 Wilde B, Paassen P van, Witzke O, Tervaert JW (2011) New pathophysiological insights and treatment of ANCA-associated vasculitis. Kidney Int 79:599–612 Gan P-Y, Steinmetz OM, Tan DSY et al (2010) Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis. J Am Soc Nephrol 21:925–931 Wilde B, Thewissen M, Damoiseaux J et al (2012) Th17 expansion in granulomatosis with polyangiitis (Wegener’s): the role of disease activity, immune regulation and therapy. Arthritis Res Ther 14:R227 Nogueira E, Hamour S, Sawant D et al (2010) Serum IL-17 and IL-23 levels and autoantigen-specific Th17 cells are elevated in patients with ANCA-associated vasculitis. Nephrol Dial Transplant 25:2209–2217 Patel DD, Lee DM, Kolbinger F, Antoni C (2013) Effect of IL-17 A blockade with secukinumab in autoimmune diseases. Ann Rheum Dis 72 Suppl 2:iii116–iii123 Hueber W, Sands BE, Lewitzky S et al (2012) Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn’s disease: unexpected results of a randomised, double-blind placebo-controlled trial. Gut 61:1693–700 Rustin MHA (2012) Long-term safety of biologics in the treatment of moderate-to-severe plaque psoriasis: review of current data. Br J Dermatol 167:3–11 Griffiths CEM, Strober BE, Kerkhof P van de et al (2010) Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis. N Engl J Med 362:118–128