Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases

PLoS ONE - Tập 7 Số 1 - Trang e29161
D. Wong1, Bory Kea, Rob Pesich, Brandon W. Higgs, Wei Zhu, Patrick O. Brown, Yihong Yao, David Fiorentino
1Department of Dermatology, Stanford University School of Medicine, Stanford, California, United States of America.

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AL Mammen, 2010, Dermatomyositis and polymyositis: Clinical presentation, autoantibodies, and pathogenesis., Ann N Y Acad Sci, 1184, 134, 10.1111/j.1749-6632.2009.05119.x

TP O'Hanlon, 2009, Genetic risk and protective factors for the idiopathic inflammatory myopathies., Curr Rheumatol Rep, 11, 287, 10.1007/s11926-009-0040-2

SA Greenberg, 2004, Uncertainties in the pathogenesis of adult dermatomyositis., Curr Opin Neurol, 17, 359, 10.1097/00019052-200406000-00018

K Arahata, 1984, Monoclonal antibody analysis of mononuclear cells in myopathies. I: Quantitation of subsets according to diagnosis and sites of accumulation and demonstration and counts of muscle fibers invaded by T cells., Ann Neurol, 16, 193, 10.1002/ana.410160206

G Page, 2004, Anatomic localization of immature and mature dendritic cell subsets in dermatomyositis and polymyositis: Interaction with chemokines and Th1 cytokine-producing cells., Arthritis Rheum, 50, 199, 10.1002/art.11428

B De Paepe, 2009, Role of cytokines and chemokines in idiopathic inflammatory myopathies., Curr Opin Rheumatol, 21, 610, 10.1097/BOR.0b013e3283317b31

SA Greenberg, 2010, Dermatomyositis and type 1 interferons., Curr Rheumatol Rep, 12, 198, 10.1007/s11926-010-0101-6

TB Niewold, 2009, Elevated serum interferon-alpha activity in juvenile dermatomyositis: associations with disease activity at diagnosis and after thirty-six months of therapy., Arthritis Rheum, 60, 1815, 10.1002/art.24555

EC Baechler, 2007, An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity., Mol Med, 13, 59, 10.2119/2006-00085.Baechler

RJ Walsh, 2007, Type I interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis., Arthritis Rheum, 56, 3784, 10.1002/art.22928

MS Krathen, 2008, Dermatomyositis., Curr Dir Autoimmun, 10, 313, 10.1159/000131751

AN Crowson, 1996, The role of microvascular injury in the pathogenesis of cutaneous lesions of dermatomyositis., Hum Pathol, 27, 15, 10.1016/S0046-8177(96)90132-X

JM Mascaro Jr, 1995, Membrane attack complex deposits in cutaneous lesions of dermatomyositis., Arch Dermatol, 131, 1386, 10.1001/archderm.1995.01690240040007

CM Magro, 1997, The immunofluorescent profile of dermatomyositis: a comparative study with lupus erythematosus., J Cutan Pathol, 24, 543, 10.1111/j.1600-0560.1997.tb01458.x

J Wenzel, 2005, Evidence for a role of type I interferons in the pathogenesis of dermatomyositis., Br J Dermatol, 153, 462, 10.1111/j.1365-2133.2005.06786.x

J Wenzel, 2006, Type I interferon-associated skin recruitment of CXCR3+ lymphocytes in dermatomyositis., Clin Exp Dermatol, 31, 576, 10.1111/j.1365-2230.2006.02150.x

S Shrestha, 2010, Lesional and nonlesional skin from patients with untreated juvenile dermatomyositis displays increased numbers of mast cells and mature plasmacytoid dendritic cells., Arthritis Rheum, 62, 2813, 10.1002/art.27529

JM McNiff, 2008, Plasmacytoid dendritic cells are present in cutaneous dermatomyositis lesions in a pattern distinct from lupus erythematosus., J Cutan Pathol, 35, 452, 10.1111/j.1600-0560.2007.00848.x

SA Greenberg, 2009, Similar topology of injury to keratinocytes and myofibres in dermatomyositis skin and muscle., Br J Dermatol, 160, 464, 10.1111/j.1365-2133.2008.08967.x

JP Callen, 2006, Dermatomyositis., Clin Dermatol, 24, 363, 10.1016/j.clindermatol.2006.07.001

M Caproni, 2004, Infiltrating cells, related cytokines and chemokine receptors in lesional skin of patients with dermatomyositis., Br J Dermatol, 151, 784, 10.1111/j.1365-2133.2004.06144.x

AM Saaf, 2008, Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes., PLoS One, 3, e4017, 10.1371/journal.pone.0004017

JE Gudjonsson, 2010, Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models., J Invest Dermatol, 130, 1829, 10.1038/jid.2010.36

SD Der, 1998, Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays., Proc Natl Acad Sci U S A, 95, 15623, 10.1073/pnas.95.26.15623

C Sanda, 2006, Differential gene induction by type I and type II interferons and their combination., J Interferon Cytokine Res, 26, 462, 10.1089/jir.2006.26.462

S Indraccolo, 2007, Identification of genes selectively regulated by IFNs in endothelial cells., J Immunol, 178, 1122, 10.4049/jimmunol.178.2.1122

JE Gudjonsson, 2009, Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin., J Invest Dermatol, 129, 2795, 10.1038/jid.2009.173

Y Yao, 2009, Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus., Arthritis Rheum, 60, 1785, 10.1002/art.24557

DA Plager, 2007, Early cutaneous gene transcription changes in adult atopic dermatitis and potential clinical implications., Exp Dermatol, 16, 28, 10.1111/j.1600-0625.2006.00504.x

SA Greenberg, 2005, Interferon-alpha/beta-mediated innate immune mechanisms in dermatomyositis., Ann Neurol, 57, 664, 10.1002/ana.20464

Z Tezak, 2002, Gene expression profiling in DQA1*0501+ children with untreated dermatomyositis: a novel model of pathogenesis., J Immunol, 168, 4154, 10.4049/jimmunol.168.8.4154

Y Yao, 2008, Type I interferon: potential therapeutic target for psoriasis?, PLoS One, 3, e2737, 10.1371/journal.pone.0002737

J Wenzel, 2008, An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in “interface dermatitis”., J Invest Dermatol, 128, 2392, 10.1038/jid.2008.96

M Ghoreishi, 2010, Type 1 interferon signature in the scalp lesions of alopecia areata., Br J Dermatol, 163, 57, 10.1111/j.1365-2133.2010.09775.x

RD Sontheimer, 2002, Dermatomyositis: an overview of recent progress with emphasis on dermatologic aspects., Dermatol Clin, 20, 387, 10.1016/S0733-8635(02)00021-9

A Milano, 2008, Molecular subsets in the gene expression signatures of scleroderma skin., PLoS One, 3, e2696, 10.1371/journal.pone.0002696