Interactions of the Dipeptide Ester Prodrugs of Acyclovir with the Intestinal Oligopeptide Transporter: Competitive Inhibition of Glycylsarcosine Transport in Human Intestinal Cell Line-Caco-2
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Anand BS, Nashed YE, and Mitra AK (2002b) Novel dipeptide prodrugs of acyclovir for ocular herpes infections: bioreversion, antiviral activity, and transport across rabbit cornea. Curr Eye Res, in press..
Beauchamp, 1992, Amino acid ester prodrugs of acyclovir., Antiviral Chem Chemother, 3, 157, 10.1177/095632029200300305
Dantzig, 1990, Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2., Biochim Biophys Acta, 1027, 211, 10.1016/0005-2736(90)90309-C
de Vrueh, 1998, Transport of l-valine-acyclovir via the oligopeptide transporter in the human intestinal cell line, Caco-2., J Pharmacol Exp Ther, 286, 1166
Easty DL (1985) Clinical Aspects of Ocular Herpes Simplex Virus Infection. (Chicago Year Book Medical Publishers, Chicago).
Goldmeier, 1988, Psychosocial implications of recurrent genital herpes simplex virus infection., Genitourin Med, 64, 327
Green MT Dunkel E (1985) Herpes Simplex Virus Infections. (Lea & Febiger, Philadelphia, PA).
Guo, 1999, Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line., J Pharmacol Exp Ther, 289, 448
Hidalgo, 1989, Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability., Gastroenterology, 96, 736, 10.1016/0016-5085(89)90897-4
Hughes, 1993, Effect of acylation on the ocular disposition of acyclovir. II: Corneal permeability and anti-HSV 1 activity of 2′-esters in rabbit epithelial keratitis., J Ocul Pharmacol, 9, 299, 10.1089/jop.1993.9.299
Lister, 1997, The influence of luminal pH on transport of neutral and charged dipeptides by rat small intestine, in vitro., Biochim Biophys Acta, 1324, 245, 10.1016/S0005-2736(96)00230-1
Lupia, 1993, Comparative pharmacokinetics of two prodrugs of zidovudine in rabbits: enhanced levels of zidovudine in brain tissue., Antimicrob Agents Chemother, 37, 818, 10.1128/AAC.37.4.818
Sakaeda, 2001, Conjugation with l-glutamate for in vivo brain drug delivery., J Drug Target, 9, 23, 10.3109/10611860108995630
Sanitato, 1984, Acyclovir in the treatment of herpetic stromal disease., Am J Ophthalmol, 98, 537, 10.1016/0002-9394(84)90237-X
Sawada, 1999, Recognition of L-amino acid ester compounds by rat peptide transporters PEPT1 and PEPT2., J Pharmacol Exp Ther, 291, 705
Temple, 1996, A model for the kinetics of neutral and anionic dipeptide-proton cotransport by the apical membrane of rat kidney cortex., J Physiol (Lond), 494, 795, 10.1113/jphysiol.1996.sp021533