Interaction of Recombinant Interleukin-2 with Liposomal Bilayers

Storm, 1995, Novel developments in liposomal delivery of peptides and proteins, J. Controlled Release, 36, 19, 10.1016/0168-3659(95)00047-C Lo, 1995, Protein location in liposomes, a drug carrier: A prediction by differential scanning calorimetry, J. Pharm. Sci., 84, 805, 10.1002/jps.2600840705 De Kroon, 1990, The role of charge and hydrophobicity in peptide-lipid interaction: A comparative study based on tryptophan fluorescence measurements combined with the use of aqueous and hydrophobic quenchers, Biochemistry, 29, 8229, 10.1021/bi00488a006 Bergers, 1993, The role of protein charge in protein–lipid interactions: pH-dependent changes of the electrophoretic mobility of liposomes through adsorption of water-soluble, globular proteins, Biochemistry, 32, 4641, 10.1021/bi00068a023 Cevc, 1990, Molecular mechanism of protein interaction with the lipid bilayer membrane, Studia Biophys., 138, 57 Collins, 1994, Interaction of recombinant granulocyte colony stimulating factor with lipid membranes: Enhanced stability of a water-soluble protein after membrane insertion, Biochem. Wash., 33, 4521, 10.1021/bi00181a012 Koppenhagen, F. J. Liposomes as delivery system for recombinant interleukin-2 in anticancer immunotherapy. Thesis Utrecht University, The Netherlands. Loeffler, 1991, Antitumor effects of interleukin 2 liposomes and anti- CD3-stimulated T-cells against murine MCA-38 hepatic metastases, Cancer Res., 51, 2127 Konno, 1991, Inhibition of growth of rat hepatoma by local injection of liposomes containing recombinant interleukin-2, Biotherapy, 3, 211, 10.1007/BF02171684 Konno, 1992, Effect of liposomal interleukin-2 on ascites forming rat hepatoma, J. Surg. Oncol., 51, 33, 10.1002/jso.2930510110 Anderson, 1990, Increased local antitumor effects of interleukin 2 liposomes in mice with MCA-106 sarcoma pulmonary metastases, Cancer Res., 50, 1853 Anderson, 1992, Interleu-kin-2 in liposomes: Increased intravenous potency and less pulmonary toxicity in the rat, Drug Dev. Res., 27, 15, 10.1002/ddr.430270103 Anderson, 1992, Depot characteristics and biodistribution of interleukin-2 liposomes: importance of route of administration, J. Immunother., 12, 19, 10.1097/00002371-199207000-00003 Bligh, 1956, W. A rapid method of total lipid extraction and purification, Biochem. Physiol., 37, 911 Visser, 1994, New reference compound with single, ultrashort lifetime for time-resolved tryptophan fluorescence measurements, Proc. SPIE, 2137, 618, 10.1117/12.182707 Beechem, 1991, The global analysis of fluorescence intensity and anisotropy decay data: second generation theory and programs, II, 241 Livesey, 1987, Analyzing the distribution of decay constants in pulse fluorometry using the maximum entropy method, Biophys. J., 52, 693, 10.1016/S0006-3495(87)83264-2 Bastiaens, 1992, Conformational dynamics and intersubunit energy transfer in wild-type and mutant lipoamide dehydrogenase from Azotobacter vinelandii. A multi-dimensional time-resolved polarized fluorescence study, Biophys. J., 63, 839, 10.1016/S0006-3495(92)81659-4 Visser, 1994, Fluorescence dynamics of staphylococcal nuclease in aqueous solution and reversed micelles, Biochim. Biophys. Acta, 1204, 225, 10.1016/0167-4838(94)90012-4 Fleury, 1995, Preparation and characterization of dipalmitoylphosphati- dylcholine liposomes containing interleukin-2, Braz. J. Med. Biol. Res., 28, 519 Atkins, 1991, Time-resolved studies of genetically engineered Escherichia coli Glutamine Synthetase. Effects of ATP on the tryptophan-57 loop, Biochemistry, 30, 3406, 10.1021/bi00228a008 Advant, 1995, The effect of pH and temperature on the self-association of recombinant human interleukin-2 as studied by equillibrium sedimentation, Pharm. Res., 12, 637, 10.1023/A:1016286920643 Arakawa, 1994, Structure and solubility of interleukin-2 in sodium dodecyl sulphate, Int. J. Pept. Protein Res., 43, 583, 10.1111/j.1399-3011.1994.tb00560.x Brochon, 1993, Analysis of a recombinant protein preparation on physical homogeneity and state of aggregation, Anal. Chem., 65, 1028, 10.1021/ac00056a014 Dryden, 1991, Evidence for an acid induced molten globule state in interleukin-2; a fluorescence and circular dichroism study, Biochim. Biophys. Acta, 1078, 94, 10.1016/0167-4838(91)90097-J Mach, 1995, Interaction of partially structured states of acidic fibroblast growth factor with phospholipid membranes, Biochemistry, 34, 9913, 10.1021/bi00031a013