Intensity-modulated Radiation Therapy for Anal Cancer

Jason A. Call1, B.M. Prendergast2, Lindsay G. Jensen3, Celine Bicquart Ord4, Karyn A. Goodman5, Rojymon Jacob2, Loren K. Mell3, Charles R. Thomas4, Salma K. Jabbour6, Robert C. Miller7
1Rutgers, The State University of New Jersey, New Brunswick, United States
2University of Alabama at Birmingham
3University of california at San Diego
4Oregon Health and Science University
5Memorial Sloan- Kettering Cancer Center
6Rutgers, The State University of New Jersey, New Brunswick;
7Mayo Clinic Rochester-MN

Tóm tắt

Từ khóa


Tài liệu tham khảo

UKCCCR Anal Cancer Trial Working, 1996, UK Co-ordinating Committee on Cancer Research. Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin., Lancet, 348, 1049, 10.1016/S0140-6736(96)03409-5

Ajani, 2008, . Fluorouracil, mitomycin, and radiotherapy vs. fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial., JAMA, 299, 1914, 10.1001/jama.299.16.1914

Bartelink, 1997, . Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups., J Clin Oncol, 15, 2040, 10.1200/JCO.1997.15.5.2040

Flam, 1996, . Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study., J Clin Oncol, 14, 2527, 10.1200/JCO.1996.14.9.2527

Kachnic, 2009, . Radiation Therapy Oncology Group. A phase II evaluation of dose-painted IMRT in combination with 5-fluorouracil and mitomycin-C for reduction of acute morbidity in carcinoma of the anal canal., Int J Radiat Oncol Biol Phys, 75, S5, 10.1016/j.ijrobp.2009.07.038

Kachnic, 2010, . Early efficacy results of RTOG 0529: a phase II evaluation of dose-painted IMRT in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal., Int J Radiat Oncol Biol Phys, 78, S55, 10.1016/j.ijrobp.2010.07.162

Kachnic, 2012, . Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy., Int J Radiat Oncol Biol Phys, 82, 153, 10.1016/j.ijrobp.2010.09.030

Milano, 2005, . Intensity-modulated radiation therapy (IMRT) in the treatment of anal cancer: toxicity and clinical outcome., Int J Radiat Oncol Biol Phys, 63, 354, 10.1016/j.ijrobp.2005.02.030

Pepek, 2010, . Intensity-modulate radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis., Int J Radiat Oncol Biol Phys, 78, 1413, 10.1016/j.ijrobp.2009.09.046

Salama, 2007, . Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience., J Clin Oncol, 25, 4581, 10.1200/JCO.2007.12.0170

Call, 2013, . Concurrent chemotherapy and intensity modulated radiation therapy in the treatment of anal cancer: a retrospective review from a large academic center., Pract Radiat Oncol, 3, 26, 10.1016/j.prro.2012.02.005

Bazan, 2011, . Intensity-modulated radiation therapy versus conventional radiation therapy for squamous cell carcinoma of the anal canal., Cancer, 117, 3342, 10.1002/cncr.25901

James, 2009, . A randomized trial of chemoradiation using mitomycin or cisplatin, with or without maintenance cisplatin5FU in squamous cell carcinoma of the anus (ACT II)., J Clin Oncol, 27, 2, 10.1200/jco.2009.27.15_suppl.lba4009

Mell, 2006, . Dosimetric predictors of acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity modulated radiation therapy (IMRT)., Int J Radiat Oncol Biol Phys, 66, S277, 10.1016/j.ijrobp.2006.07.525

Mell, 2008, . Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy., Int J Radiat Oncol Biol Phys, 70, 1431, 10.1016/j.ijrobp.2007.08.074

Brixey, 2002, . Impact of intensity-modulated radiotherapy on acute hematologic toxicity in women with gynecologic malignancies., Int J Radiat Oncol Biol Phys, 54, 1388, 10.1016/S0360-3016(02)03801-4