Integrated boost IMRT with FET-PET-adapted local dose escalation in glioblastomas

Springer Science and Business Media LLC - Tập 188 Số 4 - Trang 334-339 - 2012
Marc D. Piroth1,2, Michael Pinkawa1,2, Richard Holý1,2, Jens Klotz1,2, S. Schaar1,2, Gabriele Stoffels3,2, Norbert Galldiks4,3, Heinz H. Coenen3,2, Hartmut Kaiser5, Karl‐Josef Langen3,2, Michael J. Eble1,2
1Department of Radiation Oncology, RWTH Aachen University Hospital, Aachen, Germany
2Jülich-Aachen Research Alliance (JARA) – Section JARA-Brain, Forschungszentrum Jülich, Jülich, Germany
3Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany
4Department of Neurology, University Hospital Cologne, Cologne, Germany
5Department of Nuclear Medicine, RWTH Aachen University Hospital, Aachen, Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Balducci M, Apicella G, Manfrida S et al (2010) Single-arm phase II study of conformal radiation therapy and temozolomide plus fractionated stereotactic conformal boost in high-grade gliomas: final report. Strahlenther Onkol 186:558–564

Baumert BG, Lutterbach J, Bernays R et al (2003) Fractionated stereotactic radiotherapy boost after post-operative radiotherapy in patients with high-grade gliomas. Radiother Oncol 67:183–190

Blonigen BJ, Steinmetz RD, Levin L et al (2010) Irradiated volume as a predictor of brain radionecrosis after linear accelerator stereotactic radiosurgery. Int J Radiat Oncol Biol Phys 77:996–1001

Cardinale R, Won M, Choucair A et al (2006) A phase II trial of accelerated radiotherapy using weekly stereotactic conformal boost for supratentorial glioblastoma multiforme: RTOG 0023. Int J Radiat Oncol Biol Phys 65:1422–1428

Chan JL, Lee SW, Fraass BA et al (2002) Survival and failure patterns of high-grade gliomas after three-dimensional conformal radiotherapy. J Clin Oncol 20:1635–1642

Fowler JF (1989) The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 62:679–694

Gerstein J, Franz K, Steinbach JP et al (2011) Radiochemotherapy with temozolomide for patients with glioblastoma: prognostic factors and long-term outcome of unselected patients from a single institution. Strahlenther Onkol 187:722–728

Grosu AL, Weber WA, Franz M et al (2005) Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy. Int J Radiat Oncol Biol Phys 63:511–519

Guckenberger M, Mayer M, Buttmann M et al (2011) Prolonged survival when temozolomide is added to accelerated radiotherapy for glioblastoma multiforme. Strahlenther Onkol 187:548–554

Hamacher K, Coenen HH (2002) Efficient routine production of the 18F-labelled amino acid O-2–18F fluoroethyl-L-tyrosine. Appl Radiat Isot 57:853–856

Langen KJ, Hamacher K, Weckesser M et al (2006) O-(2-[18F]fluoroethyl)-L-tyrosine: uptake mechanisms and clinical applications. Nucl Med Biol 33:287–294

Lee SW, Fraass BA, Marsh LH et al (1999) Patterns of failure following high-dose 3-D conformal radiotherapy for high-grade astrocytomas: a quantitative dosimetric study. Int J Radiat Oncol Biol Phys 43:79–88

Macdonald DR, Cascino TL, Schold SC Jr et al (1990) Response criteria for phase II studies of supratentorial malignant glioma. J Clin Oncol 8:1277–1280

Milano MT, Okunieff P, Donatello RS et al (2010) Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma. Int J Radiat Oncol Biol Phys 78:1147–1155

Oppitz U, Maessen D, Zunterer H et al (1999) 3D-recurrence-patterns of glioblastomas after CT-planned postoperative irradiation. Radiother Oncol 53:53–57

Pauleit D, Floeth F, Hamacher K et al (2005) O-(2-[18F]fluoroethyl)-L-tyrosine PET combined with MRI improves the diagnostic assessment of cerebral gliomas. Brain 128:678–687

Piroth MD, Pinkawa M, Holy R et al (2009) Integrated-boost IMRT or 3-D-CRT using FET-PET based auto-contoured target volume delineation for glioblastoma multiforme – a dosimetric comparison. Radiat Oncol 4:57

Piroth MD, Pinkawa M, Holy R et al (2011) Prognostic value of early 18F-fluoroethylthyrosine PET after radiochemotherapy in glioblastoma multiforme. Int J Radiat Oncol Biol Phys 80:176–184

Piroth MD, Holy R, Pinkawa M et al (2011) Prognostic impact of postoperative, pre-irradiation 18F-fluoroethyl-L-tyrosine uptake in glioblastoma patients treated with radiochemotherapy. Radiother Oncol 99:218–224

Rickhey M, Koelbl O, Eilles C et al (2008) A biologically adapted dose-escalation approach, demonstrated for 18F-FET-PET in brain tumors. Strahlenther Onkol 184:536–542

Rickhey M, Moravek Z, Eilles C et al (2010) 18F-FET-PET-based dose painting by numbers with protons. Strahlenther Onkol 186:320–326

Roesch P, Netsch T, McNutt T et al (2003) Syntegra – automated image registration algorithms. Philips White Paper

Shrieve DC, Alexander E III, Black PM et al (1999) Treatment of patients with primary glioblastoma multiforme with standard postoperative radiotherapy and radiosurgical boost: prognostic factors and long-term outcome. J Neurosurg 90:72–77

Souhami L, Seiferheld W, Brachman D et al (2004) Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol. Int J Radiat Oncol Biol Phys 60:853–860

Stupp R, Mason WP, Bent MJ van den et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987–996

Stupp R, Hegi ME, Mason WP et al (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10:459–466

Tsien C, Moughan J, Michalski JM et al (2009) Phase I three-dimensional conformal radiation dose escalation study in newly diagnosed glioblastoma: radiation therapy oncology group trial 98-03. Int J Radiat Oncol Biol Phys 73:699–708

Walker MD, Strike TA, Sheline GE (1979) Analysis of dose-effect relationship in the radiotherapy of malignant gliomas. Int J Radiat Oncol Biol Phys 5:1725–1731

Walker MD, Alexander E Jr, Hunt WE et al (1978) Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg 49:333–343

Weber DC, Casanova N, Zilli T et al (2009) Recurrence pattern after [(18)F]fluoroethyltyrosine-positron emission tomography-guided radiotherapy for high-grade glioma: a prospective study. Radiother Oncol 93:586–592

Wen PY, Macdonald DR, Reardon DA et al (2010) Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group. J Clin Oncol 28:1963–1972

Wick A, Felsberg J, Steinbach JP et al (2007) Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent glioma. J Clin Oncol 25:3357–3361