Integrated approaches to understanding antipsychotic drug action at GPCRs
Tài liệu tham khảo
Carlsson, 1987, Perspectives on the discovery of central monoaminergic neurotransmission, Annu Rev Neurosci, 10, 19, 10.1146/annurev.ne.10.030187.000315
Gainetdinov, 1999, Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity, Science, 283, 397, 10.1126/science.283.5400.397
Birkmayer, 1961, The L-3,4-dioxyphenylalanine (DOPA)-effect in Parkinson-akinesia, Wien Klin Wochenschr, 73, 787
Delgado, 2000, Depression: the case for a monoamine deficiency, J Clin Psychiatry, 61, 7
Davis, 1991, Dopamine in schizophrenia: a review and reconceptualization, Am J Psychiatry, 148, 1474, 10.1176/ajp.148.11.1474
Carlsson, 2001, Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence, Annu Rev Pharmacol Toxicol, 41, 237, 10.1146/annurev.pharmtox.41.1.237
Meltzer, 2004, What's atypical about atypical antipsychotic drugs?, Curr Opin Pharmacol, 4, 53, 10.1016/j.coph.2003.09.010
Creese, 1976, Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs, Science, 192, 481, 10.1126/science.3854
Seeman, 1976, Antipsychotic drug doses and neuroleptic/dopamine receptors, Nature, 261, 717, 10.1038/261717a0
Meltzer, 1989, Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values, J Pharmacol Exp Ther, 251, 238
Meltzer, 2003, Serotonin receptors: their key role in drugs to treat schizophrenia, Prog Neuropsychopharmacol Biol Psychiatry, 27, 1159, 10.1016/j.pnpbp.2003.09.010
Miyamoto, 2005, Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs, Mol Psychiatry, 10, 79, 10.1038/sj.mp.4001556
McFarland, 2011, Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease, Behav Pharmacol, 22, 681, 10.1097/FBP.0b013e32834aff98
Simon, 1991, Diversity of G proteins in signal transduction, Science, 252, 802, 10.1126/science.1902986
Neves, 2002, G protein pathways, Science, 296, 1636, 10.1126/science.1071550
Sheu, 1993, Measurement of intracellular calcium using bioluminescent aequorin expressed in human cells, Anal Biochem, 209, 343, 10.1006/abio.1993.1132
Fitzgerald, 1999, Measurement of responses from Gi-, Gs-, or Gq-coupled receptors by a multiple response element/cAMP response element-directed reporter assay, Anal Biochem, 275, 54, 10.1006/abio.1999.4295
Adams, 1991, Fluorescence ratio imaging of cyclic AMP in single cells, Nature, 349, 694, 10.1038/349694a0
Ponsioen, 2004, Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator, EMBO Rep, 5, 1176, 10.1038/sj.embor.7400290
Xu, 1999, A bioluminescence resonance energy transfer (BRET) system: application to interacting circadian clock proteins, Proc Natl Acad Sci U S A, 96, 151, 10.1073/pnas.96.1.151
Barak, 2008, Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor, Mol Pharmacol, 74, 585, 10.1124/mol.108.048884
Weiner, 2001, 5-hydroxytryptamine2A receptor inverse agonists as antipsychotics, J Pharmacol Exp Ther, 299, 268
Newman-Tancredi, 2005, Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia, Int J Neuropsychopharmacol, 8, 341, 10.1017/S1461145704005000
Newman-Tancredi, 2011, Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties, Psychopharmacology (Berl), 216, 451, 10.1007/s00213-011-2247-y
Lefkowitz, 2005, Transduction of receptor signals by beta-arrestins, Science, 308, 512, 10.1126/science.1109237
Lohse, 1990, beta-Arrestin: a protein that regulates beta-adrenergic receptor function, Science, 248, 1547, 10.1126/science.2163110
Ferguson, 1996, Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization, Science, 271, 363, 10.1126/science.271.5247.363
Luttrell, 1999, Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes, Science, 283, 655, 10.1126/science.283.5402.655
Tohgo, 2002, beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation, J Biol Chem, 277, 9429, 10.1074/jbc.M106457200
Ahn, 2004, Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor, J Biol Chem, 279, 35518, 10.1074/jbc.M405878200
Oakley, 1999, Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization, J Biol Chem, 274, 32248, 10.1074/jbc.274.45.32248
Violin, 2007, Beta-arrestin-biased ligands at seven-transmembrane receptors, Trends Pharmacol Sci, 28, 416, 10.1016/j.tips.2007.06.006
Urban, 2007, Functional selectivity and classical concepts of quantitative pharmacology, J Pharmacol Exp Ther, 320, 1, 10.1124/jpet.106.104463
Bohn, 2003, Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice, J Neurosci, 23, 10265, 10.1523/JNEUROSCI.23-32-10265.2003
Beaulieu, 2005, An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior, Cell, 122, 261, 10.1016/j.cell.2005.05.012
Masri, 2008, Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics, Proc Natl Acad Sci U S A, 105, 13656, 10.1073/pnas.0803522105
Klewe, 2008, Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling, Neuropharmacology, 54, 1215, 10.1016/j.neuropharm.2008.03.015
Bhatnagar, 2001, The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis, J Biol Chem, 276, 8269, 10.1074/jbc.M006968200
Schmid, 2008, Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo, Proc Natl Acad Sci U S A, 105, 1079, 10.1073/pnas.0708862105
Powell, 2007, Overview of animal models of schizophrenia, Curr Protoc Neurosci, 24
van den Buuse, 2010, Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects, Schizophr Bull, 36, 246, 10.1093/schbul/sbp132
Lieberman, 2008, Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection, Pharmacol Rev, 60, 358, 10.1124/pr.107.00107
Weiner, 1984, Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats, Psychopharmacology (Berl), 83, 194, 10.1007/BF00429734
King, 1998, Drug treatment of the negative symptoms of schizophrenia, Eur Neuropsychopharmacol, 8, 33, 10.1016/S0924-977X(97)00041-2
Abi-Dargham, 2005, Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies, Eur Psychiatry, 20, 15, 10.1016/j.eurpsy.2004.11.003
Kirkpatrick, 2006, The NIMH-MATRICS consensus statement on negative symptoms, Schizophr Bull, 32, 214, 10.1093/schbul/sbj053
Kellendonk, 2006, Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning, Neuron, 49, 603, 10.1016/j.neuron.2006.01.023
Giros, 1996, Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter, Nature, 379, 606, 10.1038/379606a0
Mohn, 1999, Mice with reduced NMDA receptor expression display behaviors related to schizophrenia, Cell, 98, 427, 10.1016/S0092-8674(00)81972-8
Jaaro-Peled, 2009, Gene models of schizophrenia: DISC1 mouse models, Prog Brain Res, 179, 75, 10.1016/S0079-6123(09)17909-8
Allen, 2011, Discovery of beta-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy, Proc Natl Acad Sci U S A, 108, 18488, 10.1073/pnas.1104807108
Kinkead, 2004, Neurotensin, schizophrenia, and antipsychotic drug action, Int Rev Neurobiol, 59, 327, 10.1016/S0074-7742(04)59013-X
Woolley, 2008, The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity, Psychopharmacology (Berl), 196, 431, 10.1007/s00213-007-0974-x
Miyamoto, 2013, Alternative pharmacologic targets for the treatment of schizophrenia: results from phase I and II trials, Curr Opin Psychiatry, 26, 158, 10.1097/YCO.0b013e32835d8296
McOmish, 2012, Clozapine-induced locomotor suppression is mediated by 5-HT2A receptors in the forebrain, Neuropsychopharmacology, 37, 2747, 10.1038/npp.2012.139
Bay-Richter, 2013, D-amphetamine and antipsychotic drug effects on latent inhibition in mice lacking dopamine D2 receptors, Neuropsychopharmacology, 38, 1512, 10.1038/npp.2013.50
Ralph-Williams, 2002, Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice, J Neurosci, 22, 9604, 10.1523/JNEUROSCI.22-21-09604.2002
Bortolozzi, 2010, Dopamine release induced by atypical antipsychotics in prefrontal cortex requires 5-HT(1A) receptors but not 5-HT(2A) receptors, Int J Neuropsychopharmacol, 13, 1299, 10.1017/S146114571000009X
Gong, 2003, A gene expression atlas of the central nervous system based on bacterial artificial chromosomes, Nature, 425, 917, 10.1038/nature02033
Lee, 2006, Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens, Proc Natl Acad Sci U S A, 103, 3399, 10.1073/pnas.0511244103
Gong, 2007, Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs, J Neurosci, 27, 9817, 10.1523/JNEUROSCI.2707-07.2007
Bateup, 2010, Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors, Proc Natl Acad Sci U S A, 107, 14845, 10.1073/pnas.1009874107
Greengard, 2001, The neurobiology of slow synaptic transmission, Science, 294, 1024, 10.1126/science.294.5544.1024
Bateup, 2008, Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs, Nat Neurosci, 11, 932, 10.1038/nn.2153
Urs, 2012, Deletion of GSK3beta in D2R-expressing neurons reveals distinct roles for beta-arrestin signaling in antipsychotic and lithium action, Proc Natl Acad Sci U S A, 109, 20732, 10.1073/pnas.1215489109
Beaulieu, 2004, Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade, Proc Natl Acad Sci U S A, 101, 5099, 10.1073/pnas.0307921101
Beaulieu, 2007, Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo, J Neurosci, 27, 881, 10.1523/JNEUROSCI.5074-06.2007
Wadenberg, 1996, Serotonergic mechanisms in neuroleptic-induced catalepsy in the rat, Neurosci Biobehav Rev, 20, 325, 10.1016/0149-7634(95)00057-7
Doyle, 2008, Application of a translational profiling approach for the comparative analysis of CNS cell types, Cell, 135, 749, 10.1016/j.cell.2008.10.029
Heiman, 2008, A translational profiling approach for the molecular characterization of CNS cell types, Cell, 135, 738, 10.1016/j.cell.2008.10.028
Sanz, 2009, Cell-type-specific isolation of ribosome-associated mRNA from complex tissues, Proc Natl Acad Sci U S A, 106, 13939, 10.1073/pnas.0907143106
Cloonan, 2008, Stem cell transcriptome profiling via massive-scale mRNA sequencing, Nat Methods, 5, 613, 10.1038/nmeth.1223
Bottomly, 2011, Evaluating gene expression in C57BL/6J and DBA/2J mouse striatum using RNA-Seq and microarrays, PLoS ONE, 6, e17820, 10.1371/journal.pone.0017820
MacDonald, 2005, Antipsychotic drugs elevate mRNA levels of presynaptic proteins in the frontal cortex of the rat, Biol Psychiatry, 57, 1041, 10.1016/j.biopsych.2005.01.022
Thomas, 2003, Antipsychotic drug treatment alters expression of mRNAs encoding lipid metabolism-related proteins, Mol Psychiatry, 8, 983, 10.1038/sj.mp.4001425
Gygi, 2000, Mass spectrometry and proteomics, Curr Opin Chem Biol, 4, 489, 10.1016/S1367-5931(00)00121-6
Xiao, 2007, Functional specialization of beta-arrestin interactions revealed by proteomic analysis, Proc Natl Acad Sci U S A, 104, 12011, 10.1073/pnas.0704849104
Xiao, 2010, Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR), Proc Natl Acad Sci U S A, 107, 15299, 10.1073/pnas.1008461107
Choi-Rhee, 2004, Promiscuous protein biotinylation by Escherichia coli biotin protein ligase, Protein Sci, 13, 3043, 10.1110/ps.04911804
Roux, 2012, A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells, J Cell Biol, 196, 801, 10.1083/jcb.201112098