Inositol-requiring enzyme 1 alpha endoribonuclease specific inhibitor STF-083010 protects the liver from thioacetamide-induced oxidative stress, inflammation and injury by triggering hepatocyte autophagy

International Immunopharmacology - Tập 73 - Trang 261-269 - 2019
Feng Zhan1,2, Guoping Zhao1,3, Xu Li1, Shikun Yang1, Wenjie Yang1, Shun Zhou1, Feng Zhang1
1Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
2Department of Hepatobiliary and Laparoscopic Surgery, The Affiliated Yixing Hospital of Jiangsu University, Yixing 214200, China
3Department of General Surgery, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 210029, China

Tài liệu tham khảo

Levada, 2018, Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling, J. Hepatol., 68, 996, 10.1016/j.jhep.2018.01.003

Wen, 2018, Piceatannol attenuates D-GalN/LPS-induced hepatoxicity in mice: involvement of ER stress, inflammation and oxidative stress, Int. Immunopharmacol., 64, 131, 10.1016/j.intimp.2018.08.037

Kang, 2008, Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity, Toxicol. Appl. Pharmacol., 228, 295, 10.1016/j.taap.2007.11.010

Homma, 2018, Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury, Toxicol. Lett., 294, 37, 10.1016/j.toxlet.2018.05.015

Malhotra, 2007, Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?, Antioxid. Redox Signal., 9, 2277, 10.1089/ars.2007.1782

Zhang, 2008, From endoplasmic-reticulum stress to the inflammatory response, Nature, 454, 455, 10.1038/nature07203

Cao, 2014, Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease, Antioxid. Redox Signal., 21, 396, 10.1089/ars.2014.5851

Yu, 2011, Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling, Hepatology, 54, 979, 10.1002/hep.24469

Dara, 2011, The contribution of endoplasmic reticulum stress to liver diseases, Hepatology, 53, 1752, 10.1002/hep.24279

Hur, 2012, IRE1alpha activation protects mice against acetaminophen-induced hepatotoxicity, J. Exp. Med., 209, 307, 10.1084/jem.20111298

Han, 2016, PHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1-Xbp1s pathway expedites liver injury, Gut, 65, 1377, 10.1136/gutjnl-2014-308506

Lebeaupin, 2018, Bax inhibitor-1 protects from nonalcoholic steatohepatitis by limiting inositol-requiring enzyme 1 alpha signaling in mice, Hepatology, 68, 515, 10.1002/hep.29847

Chen, 2018, Inositol-requiring enzyme 1 alpha endoribonuclease specific inhibitor STF-083010 alleviates carbon tetrachloride induced liver injury and liver fibrosis in mice, Front. Pharmacol., 9, 1344, 10.3389/fphar.2018.01344

Klionsky, 2007, Autophagy: from phenomenology to molecular understanding in less than a decade, Nat. Rev. Mol. Cell Biol., 8, 931, 10.1038/nrm2245

Hadj Abdallah, 2018, Zinc mitigates renal ischemia-reperfusion injury in rats by modulating oxidative stress, endoplasmic reticulum stress, and autophagy, J. Cell. Physiol., 233, 8677, 10.1002/jcp.26747

Lee, 2012, Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling, Biochem. J., 441, 523, 10.1042/BJ20111451

San-Miguel, 2015, Melatonin inhibits autophagy and endoplasmic reticulum stress in mice with carbon tetrachloride-induced fibrosis, J. Pineal Res., 59, 151, 10.1111/jpi.12247

Bhogal, 2012, Autophagy: a cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress, Autophagy, 8, 545, 10.4161/auto.19012

Ni, 2012, Activation of autophagy protects against acetaminophen-induced hepatotoxicity, Hepatology, 55, 222, 10.1002/hep.24690

Senft, 2015, UPR, autophagy, and mitochondria crosstalk underlies the ER stress response, Trends Biochem. Sci., 40, 141, 10.1016/j.tibs.2015.01.002

Koh, 2018, Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress, J. Cell Sci., 131, 10.1242/jcs.217992

Adolph, 2013, Paneth cells as a site of origin for intestinal inflammation, Nature, 503, 272, 10.1038/nature12599

Hetz, 2009, XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy, Genes Dev., 23, 2294, 10.1101/gad.1830709

Papandreou, 2011, Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma, Blood, 117, 1311, 10.1182/blood-2010-08-303099

Liu, 2018, STF-083010, an inhibitor of XBP1 splicing, attenuates acute renal failure in rats by suppressing endoplasmic reticulum stress-induced apoptosis and inflammation, Exp. Anim., 67, 373, 10.1538/expanim.17-0131

Nagy, 2010, BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury, Toxicol. Appl. Pharmacol., 243, 96, 10.1016/j.taap.2009.11.017

Uzi, 2013, CHOP is a critical regulator of acetaminophen-induced hepatotoxicity, J. Hepatol., 59, 495, 10.1016/j.jhep.2013.04.024

Hinson, 2010, Mechanisms of acetaminophen-induced liver necrosis, Handb. Exp. Pharmacol., 369, 10.1007/978-3-642-00663-0_12

Zhou, 2018, Hepatoprotective effect of baicalein against acetaminophen-induced acute liver injury in mice, Molecules, 24, 10.3390/molecules24010131

Zhou, 2018, Spermine alleviates acute liver injury by inhibiting liver-resident macrophage pro-inflammatory response through ATG5-dependent autophagy, Front. Immunol., 9, 948, 10.3389/fimmu.2018.00948