Innate and adaptive effects of inflammasomes on T cell responses

Current Opinion in Immunology - Tập 25 - Trang 359-365 - 2013
Catherine Dostert1, Kristina Ludigs2, Greta Guarda2
1Life Sciences Research Unit, University of Luxembourg, 162a, Avenue de la Faïencerie, 1511 Luxembourg
2Department of Biochemistry, Chemin des Boveresses 155, 1066 Epalinges, Switzerland

Tài liệu tham khảo

Schroder, 2010, The inflammasomes, Cell, 140, 821, 10.1016/j.cell.2010.01.040 Rathinam, 2012, Regulation of inflammasome signaling, Nat Immunol, 13, 333, 10.1038/ni.2237 Keller, 2008, Active caspase-1 is a regulator of unconventional protein secretion, Cell, 132, 818, 10.1016/j.cell.2007.12.040 Lamkanfi, 2010, Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia, J Immunol, 185, 4385, 10.4049/jimmunol.1000803 Bergsbaken, 2009, Pyroptosis: host cell death and inflammation, Nat Rev Microbiol, 7, 99, 10.1038/nrmicro2070 Dinarello, 2011, Interleukin-1 in the pathogenesis and treatment of inflammatory diseases, Blood, 117, 3720, 10.1182/blood-2010-07-273417 Yazdi, 2010, Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta, Proc Natl Acad Sci USA, 107, 19449, 10.1073/pnas.1008155107 Gross, 2012, Inflammasome activators induce interleukin-1alpha secretion via distinct pathways with differential requirement for the protease function of caspase-1, Immunity, 36, 388, 10.1016/j.immuni.2012.01.018 Arend, 2008, IL-1, IL-18, and IL-33 families of cytokines, Immunol Rev, 223, 20, 10.1111/j.1600-065X.2008.00624.x Wu, 2009, BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources, Genome Biol, 10, R130, 10.1186/gb-2009-10-11-r130 Nakanishi, 2001, Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu, Cytokine Growth Factor Rev, 12, 53, 10.1016/S1359-6101(00)00015-0 Nagai, 2003, Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation, J Immunol, 171, 5233, 10.4049/jimmunol.171.10.5233 Guarda, 2011, Type I interferon inhibits interleukin-1 production and inflammasome activation, Immunity, 34, 213, 10.1016/j.immuni.2011.02.006 Veldhoen, 2006, TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells, Immunity, 24, 179, 10.1016/j.immuni.2006.01.001 Acosta-Rodriguez, 2007, Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells, Nat Immunol, 8, 942, 10.1038/ni1496 Kryczek, 2007, Cutting edge: opposite effects of IL-1 and IL-2 on the regulation of IL-17+ T cell pool IL-1 subverts IL-2-mediated suppression, J Immunol, 179, 1423, 10.4049/jimmunol.179.3.1423 Blom, 2012, IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 cultures, J Immunol, 189, 4331, 10.4049/jimmunol.1103685 Yoshimoto, 2000, IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6, Nat Immunol, 1, 132, 10.1038/77811 Shi, 2003, Molecular identification of a danger signal that alerts the immune system to dying cells, Nature, 425, 516, 10.1038/nature01991 Conforti-Andreoni, 2011, Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18, J Immunol, 187, 5842, 10.4049/jimmunol.1101408 Kool, 2011, An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma, Immunity, 34, 527, 10.1016/j.immuni.2011.03.015 Eisenbarth, 2008, Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants, Nature, 453, 1122, 10.1038/nature06939 Li, 2008, Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3, J Immunol, 181, 17, 10.4049/jimmunol.181.1.17 Franchi, 2008, The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity, Eur J Immunol, 38, 2085, 10.1002/eji.200838549 McKee, 2009, Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity, J Immunol, 183, 4403, 10.4049/jimmunol.0900164 Kool, 2012, Alum adjuvant: some of the tricks of the oldest adjuvant, J Med Microbiol, 61, 927, 10.1099/jmm.0.038943-0 Krause, 2012, The role of interleukin-1 in allergy-related disorders, Curr Opin Allergy Clin Immunol, 12, 477, 10.1097/ACI.0b013e3283574d0c Corazza, 2012, Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models, Allergy, 67, 1483 Ghiringhelli, 2009, Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors, Nat Med, 15, 1170, 10.1038/nm.2028 Sutton, 2006, A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis, J Exp Med, 203, 1685, 10.1084/jem.20060285 Matsuki, 2006, Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis, Int Immunol, 18, 399, 10.1093/intimm/dxh379 Ludigs, 2012, Type I IFN-mediated regulation of IL-1 production in inflammatory disorders, Cell Mol Life Sci, 69, 3395, 10.1007/s00018-012-0989-2 Furlan, 1999, Caspase-1 regulates the inflammatory process leading to autoimmune demyelination, J Immunol, 163, 2403, 10.4049/jimmunol.163.5.2403 Gris, 2010, NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses, J Immunol, 185, 974, 10.4049/jimmunol.0904145 Shaw, 2010, Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis, J Immunol, 184, 4610, 10.4049/jimmunol.1000217 Inoue, 2012, Interferon-beta therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome, Sci Signal, 5, ra38, 10.1126/scisignal.2002767 Goldbach-Mansky, 2011, Current status of understanding the pathogenesis and management of patients with NOMID/CINCA, Curr Rheumatol Rep, 13, 123, 10.1007/s11926-011-0165-y Meng, 2009, A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses, Immunity, 30, 860, 10.1016/j.immuni.2009.04.012 Brydges, 2009, Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity, Immunity, 30, 875, 10.1016/j.immuni.2009.05.005 Lasiglie, 2011, Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients, PLoS ONE, 6, e20014, 10.1371/journal.pone.0020014 Hitzler, 2012, Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections, which are differentially mediated by its substrates IL-1beta and IL-18, J Immunol, 188, 3594, 10.4049/jimmunol.1103212 van de Veerdonk, 2011, The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis, Eur J Immunol, 41, 2260, 10.1002/eji.201041226 Dunne, 2010, Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis, J Immunol, 185, 1711, 10.4049/jimmunol.1000105 Ritter, 2010, Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses, Proc Natl Acad Sci USA, 107, 20459, 10.1073/pnas.1010337107 Trunk, 2012, Innate instruction of CD4+ T cell immunity in respiratory bacterial infection, J Immunol, 189, 616, 10.4049/jimmunol.1200924 Saiga, 2012, Critical role of AIM2 in Mycobacterium tuberculosis infection, Int Immunol, 24, 637, 10.1093/intimm/dxs062 Zielinski, 2012, Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta, Nature, 484, 514, 10.1038/nature10957 O‘Sullivan, 2006, IL-1 beta breaks tolerance through expansion of CD25+ effector T cells, J Immunol, 176, 7278, 10.4049/jimmunol.176.12.7278 Pang, 2013, IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8(+) T cell responses to influenza A virus, Nature immunology, 14, 246, 10.1038/ni.2514 Takeda, 1998, Defective NK cell activity and Th1 response in IL-18-deficient mice, Immunity, 8, 383, 10.1016/S1074-7613(00)80543-9 Kupz, 2012, NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8(+) T cells, Nat Immunol, 13, 162, 10.1038/ni.2195 Soudja, 2012, Inflammatory monocytes activate memory CD8(+) T and innate NK lymphocytes independent of cognate antigen during microbial pathogen invasion, Immunity, 37, 549, 10.1016/j.immuni.2012.05.029 Kastenmuller, 2012, A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread, Cell, 150, 1235, 10.1016/j.cell.2012.07.021 Lalor, 2011, Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity, J Immunol, 186, 5738, 10.4049/jimmunol.1003597 Hernandez-Cuellar, 2012, Cutting edge: nitric oxide inhibits the NLRP3 inflammasome, J Immunol, 189, 5113, 10.4049/jimmunol.1202479