Injectable versatile liquid-solid transformation implants alliance checkpoint blockade for magnetothermal dynamic-immunotherapy

Materials Today Bio - Tập 16 - Trang 100442 - 2022
Mengna Wang1,2, Siyu Deng1, Yijia Cao3, Hang Zhou2, Wei Wei1, Kexiao Yu4, Youde Cao1,5,6, Bing Liang1,5,6
1Department of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, PR China
2Institute of Ultrasound Imaging of Chongqing Medical University; The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing, 400010, PR China
3Department of Digestion, University-Town Hospital of Chongqing Medical University, Chongqing, 401331, PR China
4Department of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Seventh Branch Road, Jiangbei District, Chongqing, 400021, PR China
5Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, 1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, PR China
6Department of Pathology, the First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing, 400042, PR China

Tài liệu tham khảo

Yang, 2015, Cancer immunotherapy: harnessing the immune system to battle cancer, J. Clin. Invest., 125, 3335, 10.1172/JCI83871 Xu, 2020, Exosome-based immunotherapy: a promising approach for cancer treatment, Mol. Cancer, 19, 160, 10.1186/s12943-020-01278-3 Kurup, 2019, T cell-mediated immunity to malaria, Nat. Rev. Immunol., 19, 457, 10.1038/s41577-019-0158-z Pardoll, 2012, The blockade of immune checkpoints in cancer immunotherapy, Nat. Rev. Cancer, 12, 252, 10.1038/nrc3239 Azad, 2017, PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy, EMBO Mol. Med., 9, 167, 10.15252/emmm.201606674 Upadhaya, 2021, Combinations take centre stage in PD1/PDL1 inhibitor clinical trials, Nat. Rev. Drug Discov., 20, 168, 10.1038/d41573-020-00204-y Harbeck, 2017, Breast cancer, Lancet, 389, 1134, 10.1016/S0140-6736(16)31891-8 Vagia, 2020, The landscape of targeted therapies in TNBC, Cancers (Basel), 12, 10.3390/cancers12040916 Kroemer, 2013, Immunogenic cell death in cancer therapy, Annu. Rev. Immunol., 31, 51, 10.1146/annurev-immunol-032712-100008 Li, 2022, Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency, Adv. Sci. (Weinh) Zhang, 2022, Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy, Biomaterials, 282, 10.1016/j.biomaterials.2022.121433 Xu, 2020, Enhanced ferroptosis by oxygen-boosted phototherapy based on a 2-in-1 nanoplatform of ferrous hemoglobin for tumor synergistic therapy, ACS Nano, 14, 3414, 10.1021/acsnano.9b09426 Zhao, 2022, A photosensitizer discretely loaded nanoaggregate with robust photodynamic effect for local treatment triggers systemic antitumor responses, ACS Nano, 16, 3070, 10.1021/acsnano.1c10590 Wang, 2021, A versatile gas-generator promoting drug release and oxygen replenishment for amplifying photodynamic-chemotherapy synergetic anti-tumor effects, Biomaterials, 276, 10.1016/j.biomaterials.2021.120985 Lee, 2021, Recent progress of alkyl radicals generation-based agents for biomedical applications, Adv. Healthc. Mater., 10, 10.1002/adhm.202100055 Milligan, 2019, Alkyl carbon-carbon bond formation by nickel/photoredox cross-coupling, Angew Chem. Int. Ed. Engl., 58, 6152, 10.1002/anie.201809431 Li, 2018, Supramolecular photosensitizers rejuvenate photodynamic therapy, Chem. Soc. Rev., 47, 1174, 10.1039/C7CS00594F Liang, 2022, Mitochondrial glutathione depletion nanoshuttles for oxygen-irrelevant free radicals generation: a cascaded hierarchical targeting and theranostic strategy against hypoxic tumor, ACS Appl. Mater. Interfaces, 14, 13038, 10.1021/acsami.1c24708 Gavilán, 2021, Magnetic nanoparticles and clusters for magnetic hyperthermia: optimizing their heat performance and developing combinatorial therapies to tackle cancer, Chem. Soc. Rev., 50, 11614, 10.1039/D1CS00427A Chang, 2021, Recent advances in hyperthermia therapy-based synergistic immunotherapy, Adv. Mater., 33, 10.1002/adma.202004788 Pan, 2021, Mild magnetic hyperthermia-activated innate immunity for liver cancer therapy, J. Am. Chem. Soc., 143, 8116, 10.1021/jacs.1c02537 Galluzzi, 2018, Linking cellular stress responses to systemic homeostasis, Nat. Rev. Mol. Cell Biol., 19, 731, 10.1038/s41580-018-0068-0 Liu, 2017, Synthesis and optimization of MoS(2)@Fe(3)O(4)-ICG/Pt(IV) nanoflowers for MR/IR/PA bioimaging and combined PTT/PDT/chemotherapy triggered by 808 nm laser, Adv. Sci. (Weinh), 4 Nkanga, 2020, Clinically established biodegradable long acting injectables: an industry perspective, Adv. Drug Deliv. Rev., 167, 19, 10.1016/j.addr.2020.11.008 Pelaz, 2017, Diverse applications of nanomedicine, ACS Nano, 11, 2313, 10.1021/acsnano.6b06040 Green, 2009, Immunogenic and tolerogenic cell death, Nat. Rev. Immunol., 9, 353, 10.1038/nri2545 Hayes, 2020, Oxidative stress in cancer, Cancer Cell, 38, 167, 10.1016/j.ccell.2020.06.001 Liu, 2019, Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer, Chem. Soc. Rev., 48, 2053, 10.1039/C8CS00618K Morad, 2021, Hallmarks of response, resistance, and toxicity to immune checkpoint blockade, Cell, 184, 5309, 10.1016/j.cell.2021.09.020 Kim, 2022, Adaptive immune resistance at the tumour site: mechanisms and therapeutic opportunities, Nat. Rev. Drug Discov., 21, 529, 10.1038/s41573-022-00493-5 Twyman-Saint Victor, 2015, Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer, Nature, 520, 373, 10.1038/nature14292 Zhou, 2021, A three-in-one strategy: injectable biomimetic porous hydrogels for accelerating bone regeneration via shape-adaptable Scaffolds, controllable magnesium ion release, and enhanced osteogenic differentiation, Biomacromolecules, 22, 4552, 10.1021/acs.biomac.1c00842 Zhang, 2022, Reactive oxygen species-responsive and Raman-traceable hydrogel combining photodynamic and immune therapy for postsurgical cancer treatment, Nat. Commun., 13, 4553, 10.1038/s41467-022-32160-z Zhu, 2022, Responsive hydrogels based on triggered click reactions for liver cancer, Adv. Mater. King, 2020, Endoplasmic reticulum stress: an arising target for metal-based anticancer agents, Chem. Soc. Rev., 49, 8113, 10.1039/D0CS00259C Cubillos-Ruiz, 2017, Tumorigenic and immunosuppressive effects of endoplasmic reticulum stress in cancer, Cell, 168, 692, 10.1016/j.cell.2016.12.004 Garg, 2012, ER stress-induced inflammation: does it aid or impede disease progression?, Trends Mol. Med., 18, 589, 10.1016/j.molmed.2012.06.010 Yatim, 2017, Dying cells actively regulate adaptive immune responses, Nat. Rev. Immunol., 17, 262, 10.1038/nri.2017.9 Krysko, 2012, Immunogenic cell death and DAMPs in cancer therapy, Nat. Rev. Cancer, 12, 860, 10.1038/nrc3380 Gong, 2020, DAMP-sensing receptors in sterile inflammation and inflammatory diseases, Nat. Rev. Immunol., 20, 95, 10.1038/s41577-019-0215-7 Eisenbarth, 2019, Dendritic cell subsets in T cell programming: location dictates function, Nat. Rev. Immunol., 19, 89, 10.1038/s41577-018-0088-1 Yin, 2021, Dendritic cell regulation of T helper cells, Annu. Rev. Immunol., 39, 759, 10.1146/annurev-immunol-101819-025146 Korman, 2022, The foundations of immune checkpoint blockade and the ipilimumab approval decennial, Nat. Rev. Drug Discov., 21, 509, 10.1038/s41573-021-00345-8 Friedman, 2016, Treatment of the immune-related adverse effects of immune checkpoint inhibitors: a review, JAMA Oncol., 2, 1346, 10.1001/jamaoncol.2016.1051 Speiser, 2016, Regulatory circuits of T cell function in cancer, Nat. Rev. Immunol., 16, 599, 10.1038/nri.2016.80 Kishton, 2017, Metabolic regulation of T cell longevity and function in tumor immunotherapy, Cell Metabol., 26, 94, 10.1016/j.cmet.2017.06.016 Ruterbusch, 2020, In vivo CD4(+) T cell differentiation and function: revisiting the Th1/Th2 paradigm, Annu. Rev. Immunol., 38, 705, 10.1146/annurev-immunol-103019-085803 Byrne, 2020, Tissue-resident memory T cells in breast cancer control and immunotherapy responses, Nat. Rev. Clin. Oncol., 17, 341, 10.1038/s41571-020-0333-y