Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

Nature - Tập 362 Số 6423 - Trang 841-844 - 1993
K. Jin Kim1, Bing Li2, Jane Winer2, Mark Armanini2, Nancy A. Gillett2, Heidi Phillips2, Napoleone Ferrara2
1Genentech, Incorporated, South San Francisco, California 94080
2Genentech, Inc., South San Francisco, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Klagsbrun, M. & D'Amore, P. A. A. Rev. Physiol. 53, 217–239 (1991).

Folkman, J. & Shing, Y. J. biol. Chem. 267, 10931–11934 (1992).

Folkman, J. J. natn. Cancer Inst. 82, 4–6 (1991).

Ingber, D. et al. Nature 348, 555–557 (1990).

Weidner, N., Semple, P., Welch, W. & Folkman, J. N. Engl. J. Med. 324, 1–5 (1991).

Ferrara, N., Houck, K. A., Jakeman, L. B. & Leung, D. W. Endocr. Rev. 13, 18–32 (1992).

Ferrara, N. & Henzel, W. J. Biochem. biophys. Res. Commun. 161, 851–858 (1989).

Ploüet, J., Schilling, J. & Gospodarowicz, D. EMBO J. 8, 3801–3806 (1989).

Conn, G. et al. Proc. natn. Acad. Sci. U.S.A. 87, 2628–2632 (1990).

Jakeman, L. B., Winer, J., Bennett, G. L., Altar, C. A. & Ferrara, N. J. clin. Invest. 89, 244–253 (1992).

Connolly, D. T. et al. J. biol. Chem 264, 20017–20024 (1989).

Keck, P. J. et al. Science 246, 1309–1311 (1989).

Leung, D., Cachianes, G., Kuang, W.-J., Goeddel, D. V. & Ferrara, N. Science 246, 1306–1309 (1989).

Houck, K. A. et al. Molec. Endocr. 5, 1806–1814 (1991).

Tisher, E. et al. J. biol. Chem. 266, 11947–11954 (1991).

Houck, K. A., Leung, D. W., Rowland, A. M., Winer, J. & Ferrara, N. J. biol. Chem. 267, 26031–26037 (1992).

Phillips, H. S., Hains, J., Leung, D. W. & Ferrara, N. Endocrinology 127, 965–967 (1990).

Breier, G., Albrecht, U., Sterrer, S. & Risau, W. Development 114, 521–528 (1992).

Senger, D., Perruzzi, C. A., Feder, J. & Dvorak, H. F. Cancer Res. 46, 5629 (1986).

Rosenthal, R., Megyesi, J. F., Henzel, W. J., Ferrara, N. & Folkman, J. Growth Factors 4, 53–59 (1990).

Berse, B., Brown, L. F., Van de Water, L., Dvorak, H. F. & Senger, D. R. Molec. biol. Cell 3, 211–218 (1992).

Shweiki, D., Itin, A., Soffer, D. & Keshet, E. Nature 359, 843–845 (1992).

Plate, K. H., Breier, G., Weich, H. A. & Risau, W. Nature 359, 845–847 (1992).

Berkman, R. A. et al. J. clin. Invest. 91, 153–159 (1993).

Ferrara, N. et al. J. clin. Invest. 91, 160–170 (1993).

Kim, K. J., Li, B., Houck, K., Winer, J. & Ferrara, N. Growth Factors 7, 53–64 (1992).

Lieberman, T. A. et al. EMBO J. 6, 1627–1632 (1987).

Schweigerer, L. et al. Proc. natn Acad. Sci. U.S.A. 84, 842–846 (1987).

Rizzino, A. Meth. Enzym. 146, 341–348 (1987).

Westphal, M. et al. Expl cell. Biol. 55, 152–161 (1987).

Berman, P. W. et al. J. Virol. 63, 3489–3498 (1989).

Ravindranath, N., Little-Ihrig, L., Phillips, H. S., Ferrara, N. & Zeleznick, A. J. Endocrinology 131, 254–260 (1992).