Inhibition of the NADP-linked glutamate dehydrogenase from Trypanosoma cruzi by sulfhydryl reagents

Silvia M. Juan1, Juan José Cazzulo1
1CEFOBI, Centro de Estudios Fotosintéticos y Bioquimicos (CONICET—Fundación Miguel Lillo—Universidad Nacional de Rosario), Suipacha 531, 2000 Rosario, Argentina

Tài liệu tham khảo

Blumenthal, 1973, Nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase of Neurospora—I. Isolation, subunits, amino acid composition, sulfhydryl groups and identification of a lysine residue reactive with pyridoxal phosphate and N-ethylmaleimide, J. biol. Chem., 248, 6002, 10.1016/S0021-9258(19)43499-6 Cazzulo, 1977, Glutamate dehydrogenase and aspartate aminotransferase in Trypanosoma cruzi, Comp. Biochem. Physiol., 56B, 301 Degani, 1974, Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. II. Selective chemical reactivity of amino and sulfhydryl groups, J. biol. Chem., 249, 7929, 10.1016/S0021-9258(19)42054-1 Frieden, 1963, l-glutamate dehydrogenase, Vol. 7, 3 Gutteridge, 1977, Biochemical studies on intracellular, blood and culture forms of Trypanosoma cruzi: possible targets in rational chemotherapy, 48 Hucho, 1975, Studies of glutamate dehydrogenase: analysis of functional areas and functional groups, Eur. J. Biochem., 52, 221, 10.1111/j.1432-1033.1975.tb03990.x Juan, 1978, Purification and some properties of the NADP-linked glutamate dehydrogenase from Trypanosoma cruzi, Int. J. Biochem., 9, 395, 10.1016/0020-711X(78)90052-6 Kapoor, 1977, Ligand-induced alterations in the reactivity of sulfhydryl groups and the structure of bovine liver glutamate dehydrogenase, Arch. Biochem. Biophys., 184, 518, 10.1016/0003-9861(77)90461-1