Inhibition of macrophage migration inhibitory factor prevents thyroid dysfunction in pregnant rats with acute pancreatitis

Igbinosa, 2013, Pregnancy associated pancreatitis revisited, Clin. Res. Hepatol. Gastroenterol., 37, 177, 10.1016/j.clinre.2012.07.011 Sun, 2011, Acute pancreatitis in pregnancy, Acta Obstet. Gynecol. Scand., 90, 671, 10.1111/j.1600-0412.2011.01072.x Geng, 2011, Severe acute pancreatitis during pregnancy: eleven years experience from a surgical intensive care unit, Dig. Dis. Sci., 56, 3672, 10.1007/s10620-011-1809-5 Tang, 2010, Acute pancreatitis during pregnancy, Clin. Gastroenterol. Hepatol., 8, 85, 10.1016/j.cgh.2009.08.035 Berghout, 1998, Thyroid size and thyroid function during pregnancy: an analysis, Eur. J. Endocrinol., 138, 536, 10.1530/eje.0.1380536 Rasmussen, 1989, Serum thyroglobulin during the menstrual cycle, during pregnancy, and post partum, Acta Endocrinol. (Copenh.), 121, 168, 10.1530/acta.0.1210168 Su, 2011, Maternal thyroid function in the first twenty weeks of pregnancy and subsequent fetal and infant development: a prospective population-based cohort study in China, J. Clin. Endocrinol. Metab., 96, 3234, 10.1210/jc.2011-0274 Korevaar, 2016, Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study, Lancet Diabetes Endocrinol., 4, 35, 10.1016/S2213-8587(15)00327-7 Moleti, 2014, Thyroid physiology in pregnancy, Endocr. Pract., 20, 589, 10.4158/EP13341.RA Wang, 2018, Serum thyroid hormones levels are significantly decreased in pregnant rats with acute pancreatitis, Biochem. Biophys. Res. Commun., 505, 657, 10.1016/j.bbrc.2018.09.180 Calandra, 2003, Macrophage migration inhibitory factor: a regulator of innate immunity, Nat. Rev. Immunol., 3, 791, 10.1038/nri1200 Bevilacqua, 2014, Review: putative roles for the macrophage migratory inhibitory factor at the maternal fetal interface, Placenta, 35, S51, 10.1016/j.placenta.2013.10.015 Lue, 2007, Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity, Oncogene, 26, 5046, 10.1038/sj.onc.1210318 Rahman, 2007, Serum macrophage migration inhibitory factor is an early marker of pancreatic necrosis in acute pancreatitis, Ann. Surg., 245, 282, 10.1097/01.sla.0000245471.33987.4b Sakai, 2003, Macrophage migration inhibitory factor is a critical mediator of severe acute pancreatitis, Gastroenterology, 124, 725, 10.1053/gast.2003.50099 Wang, 2019, Macrophage migration inhibitor promoted the intrahepatic bile duct injury in rats with severe acute pancreatitis, Dig. Dis. Sci., 64, 759, 10.1007/s10620-018-5379-7 Hristoskova, 2006, Macrophage migration inhibition factor is elevated in pregnancy, but not to a greater extent in preeclampsia, Arch. Gynecol. Obstet., 274, 25, 10.1007/s00404-005-0109-8 Ietta, 2002, Macrophage migration inhibitory factor in human pregnancy and labor, Am. J. Reprod. Immunol. (New York, N.Y.: 1989), 48, 404, 10.1034/j.1600-0897.2002.01152.x Pearce, 2008, Serum macrophage migration inhibitory factor in the prediction of preterm delivery, Am. J. Obstet. Gynecol., 199, e41 Al-Abed, 2011, MIF as a disease target: ISO-1 as a proof-of-concept therapeutic, Future Med. Chem., 3, 45, 10.4155/fmc.10.281 Lubetsky, 2002, The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents, J. Biol. Chem., 277, 24976, 10.1074/jbc.M203220200 Wang, 2019, The role of macrophage migration inhibitory factor in remote ischemic postconditioning, Can. J. Cardiol., 35, 501, 10.1016/j.cjca.2018.12.040 Milian, 2019, Increased intracellular proliferation in human extravillous trophoblast cells (HTR8/SVneo Line) is sequentially triggered by MIF, ERK1/2, and COX-2, Front. Microbiol., 10, 852, 10.3389/fmicb.2019.00852 Wang, 2018, Macrophage migration inhibitory factor mediates peripheral nerve injury-induced hypersensitivity by curbing dopaminergic descending inhibition, Exp. Mol. Med., 50, e445, 10.1038/emm.2017.271 Le Hiress, 2015, Proinflammatory signature of the dysfunctional endothelium in pulmonary hypertension. Role of the macrophage migration inhibitory factor/CD74 complex, Am. J. Respir. Crit. Care Med., 192, 983, 10.1164/rccm.201402-0322OC Adamali, 2012, Macrophage migration inhibitory factor enzymatic activity, lung inflammation, and cystic fibrosis, Am. J. Respir. Crit. Care Med., 186, 162, 10.1164/rccm.201110-1864OC Al-Abed, 2005, ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis, J. Biol. Chem., 280, 36541, 10.1074/jbc.C500243200 Naruoka, 2013, ISO-1, a macrophage migration inhibitory factor antagonist, prevents N-methyl-D-aspartate-induced retinal damage, Eur. J. Pharmacol., 718, 138, 10.1016/j.ejphar.2013.08.041 Guo, 2018, Fetal liver injury ameliorated by migration inhibitory factor inhibition in a rat model of acute pancreatitis in pregnancy, J. Obstetr. Gynaecol. Res., 44, 374, 10.1111/jog.13538 Li, 2019, Inhibition of macrophage migration inhibitory factor attenuates inflammation and fetal kidney injury in a rat model of acute pancreatitis in pregnancy, Int. Immunopharmacol., 68, 106, 10.1016/j.intimp.2018.12.068 Zhou, 2018, Macrophage migration inhibitory factor antagonist (S, R)3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester attenuates inflammation and lung injury in rats with acute pancreatitis in pregnancy, Mol. Med. Rep., 17, 6576 Zuo, 2016, Mitogen-activated protein kinases are activated in placental injury in rat model of acute pancreatitis in pregnancy, Pancreas, 45, 850, 10.1097/MPA.0000000000000528 Zhao, 2017, A preliminary study on fetal lung injury in a rat model of acute pancreatitis in pregnancy, Pathol. Res. Pract., 213, 1370, 10.1016/j.prp.2017.09.016 Mei, 2016, Dose-effect relationship and protective effect of MIF inhibitor on pancreas and placenta injuries in rats with acute necrotizing pancreatitis in late pregnancy, Chin. J. Emerg. Med., 25, 45 Schmidt, 1992, A better model of acute pancreatitis for evaluating therapy, Ann. Surg., 215, 44, 10.1097/00000658-199201000-00007 van Santen, 2005, The effect of cervical X-irradiation on activity index of thyrocytes and plasma TSH: a pre-clinical model for radiation-induced thyroid damage, J. Endocrinol. Invest., 28, 261, 10.1007/BF03345383 Shi, 2018, beta cells can be generated from cytokeratin 5-positive cells after cerulein-induced pancreatitis in adult mice, Biochem. Biophys. Res. Commun., 496, 114, 10.1016/j.bbrc.2018.01.008 Hong, 2016, Effects of castanospermine on inflammatory response in a rat model of experimental severe acute pancreatitis, Arch. Med. Res., 47, 436, 10.1016/j.arcmed.2016.11.007 Zhao, 2003, Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide, Free Radic. Biol. Med., 34, 1359, 10.1016/S0891-5849(03)00142-4 Dikalov, 2007, Measurement of reactive oxygen species in cardiovascular studies, Hypertension, 49, 717, 10.1161/01.HYP.0000258594.87211.6b Ducarme, 2014, Acute pancreatitis during pregnancy: a review, J. Perinatol., 34, 87, 10.1038/jp.2013.161 Zhou, 2018, SB203580 attenuates acute lung injury and inflammation in rats with acute pancreatitis in pregnancy, Inflammopharmacology De Sola, 1998, Thyroid function in acute pancreatitis, Rev. Esp. Enferm. Dig., 90, 15 Yang, 2018, Low FT3 is a valuable predictor of severe acute pancreatitis in the emergency department, J. Dig. Dis., 10.1111/1751-2980.12609 Feldt-Rasmussen, 2011, Endocrine disorders in pregnancy: physiological and hormonal aspects of pregnancy, Best Pract. Res. Clin. Endocrinol. Metab., 25, 875, 10.1016/j.beem.2011.07.004 Hu, 2015, MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis, Oncotarget, 6, 22410, 10.18632/oncotarget.4198 Callejón, 2018, Free thyroxine determination in the emergency department is a predictor of acute pancreatitis evolution:, Pancreas, 47, 1322, 10.1097/MPA.0000000000001156 Yang, 2018, Low FT3 is a valuable predictor of severe acute pancreatitis in the emergency department, J. Dig. Dis., 19, 431, 10.1111/1751-2980.12609 Alibashe-Ahmed, 2019, Macrophage migration inhibitory factor regulates TLR4 expression and modulates TCR/CD3-mediated activation in CD4+ T lymphocytes, Sci. Rep., 9, 9380, 10.1038/s41598-019-45260-6 Murata, 2018, Leptin Aggravates reflux esophagitis by increasing tissue levels of macrophage migration inhibitory factor in rats, Tohoku J. Exp. Med., 245, 45, 10.1620/tjem.245.45