Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components

Bertelli, 1996, Kinetics of trans- and cis-resveratrol (3,4′,5-trihydroxystilbene) after red wine oral administration in rats, Int. J. Clin. Pharmacol. Res., 26, 77

Berthou, 1991, Evidence for the involvement of several cytochromes P450 in the first step of caffeine metabolism by human liver microsomes, Drug. Metab. Dispos., 19, 561

Burke, 1985, Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates distinguish between different induced cytochromes P-450, Biochem. Pharmacol., 34, 33, 10.1016/0006-2952(85)90355-7

Carriere, 1993, Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone, Chem. Res. Toxicol., 6, 852, 10.1021/tx00036a015

Chan, 2000, Resveratrol, a red wine constituent, is a mechanism-based inactivator of cytochrome P450 3A4, Life Sci., 67, 3103, 10.1016/S0024-3205(00)00888-2

Chan, 1998, Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine, Life Sci., 62, 135, 10.1016/S0024-3205(98)00013-7

Chun, 1999, Resveratrol is a selective human cytochrome P450 1A1 inhibitor, Biochem. Biophys. Res. Commun., 262, 20, 10.1006/bbrc.1999.1152

Ciolino, 1999, Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP 1A1 expression by resveratrol, Mol. Pharmacol., 56, 760

Constant, 1997, Alcohol, ischemic heart disease, and the French paradox, Coronary Artery Dis., 8, 645, 10.1097/00019501-199710000-00007

Doostar, 2000, Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP 1A and CYP 1B1, Toxicology, 144, 31, 10.1016/S0300-483X(99)00215-2

Duffy, 1995, Effects of various cytochrome P-450 inducers on testosterone metabolism and several monooxygenase activities in sprague–dawley (SpD), high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats, Alcohol Alcohol., 30, 329

Fauconneau, 1997, Comparative study of radical scavenger and antioxidant properties of phenolic compounds from vitis vinifera cell cultures using in vitro tests, Life Sci., 61, 2103, 10.1016/S0024-3205(97)00883-7

Frankel, 1993, Inhibition of human LDL oxidation by resveratrol, Lancet, 341, 1103, 10.1016/0140-6736(93)92472-6

Gonzalez, 1994, Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins, Drug Metabol. Rev., 26, 165, 10.3109/03602539409029789

Gonzalez, 1990, Activation of promutagens by human cDNA expressed cytochrome P450s, Prog. Clin. Biol. Res., 340B, 77

Gonzalez, 1992, Human cytochromes P450: problems and prospects, TiPS, 131, 346

Gu, 2000, Analysis of resveratrol in wine by capillary electrophoresis, J. Chromatogr. A, 881, 471, 10.1016/S0021-9673(00)00211-9

Guengerich, 1988, Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy, Cancer Res., 48, 2946

Guengerich, 1990, Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene, Chem. Res. Toxicol., 3, 363, 10.1021/tx00016a015

He, 1998, Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice, Chem. Res. Toxicol., 11, 252, 10.1021/tx970192k

Henderson, 2000, In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus, Xenobiotica, 30, 235, 10.1080/004982500237631

Jacolot, 1991, Identification of the cytochrome P450 IIIA family as enzyme involved in the N-demethylation of tamoxifen in human liver microsomes, Biochem. Pharmacol., 41, 1911, 10.1016/0006-2952(91)90131-N

Jang, 1997, Cancer chemopreventive activity of resveratrol, a natural product derived from grapes, Science, 275, 218, 10.1126/science.275.5297.218

Kopp, 1998, Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of ‘French paradox’, Eur. J. Endocrinol., 138, 619, 10.1530/eje.0.1380619

Li, 1994, Effects of flavonoids on cytochrome P450-dependent acetaminophen metabolism in rats and human liver microsomes, Drug Metab. Dispos., 22, 566

Siess, 1995, Heterogenous effects of natural flavonoids on monooxygenase activities in human and rat liver microsomes, Toxicol. Appl. Pharm., 130, 73, 10.1006/taap.1995.1010

Soleas, 1997, Wine as a biological fluid: history, production, and role in disease prevention, J. Clin. Lab. Anal., 11, 287, 10.1002/(SICI)1098-2825(1997)11:5<287::AID-JCLA6>3.0.CO;2-4

Soleas, 1997, Resveratrol: a molecule whose time has come? and gone?, Clin. Biochem., 30, 91, 10.1016/S0009-9120(96)00155-5

Zhai, 1998, Comparative inhibition of cytochromes 450 1A1 et 1A2 by flavonoids, Drug. Metab. Dispos., 26, 989