Influenza vaccination in the elderly: improved antibody response with imuthiol (NA diethyldithiocarbamate) adjuvant therapy

Antonaci, 1985, Impairment of T immunoregulatory activities in the induction of antibody specific responses in aged humans, Mech. Ageing Devel., 30, 251, 10.1016/0047-6374(85)90115-0 Barret, 1980, Immunoregulation in aged humans, Clin. Immun. Immunopath., 17, 203, 10.1016/0090-1229(80)90088-4 Bernstein, 1983, Clinical reactions and antibody responses to influenza vaccines. A comparison of split and subunit vaccines in children and young adults, Am. J. Dis. Child., 137, 622, 10.1001/archpedi.1983.02140330006003 Brandriss, 1982, Responses of elderly subjects to a new subunit influenza virus vaccine, J. infect. Dis., 145, 277, 10.1093/infdis/145.2.277 Bruley-Rosset, 1986, Influences of sodium diethyldithiocarbamate, DTC (Imuthiol®) on T cell defective responses of aged Balb/c mice, Int. J. Immunopharmac., 8, 287, 10.1016/0192-0561(86)90110-4 Brown, 1982, Immunization against influenza in children with cancer: results of a three dose trial, J. infect. Dis., 145, 126, 10.1093/infdis/145.1.126 Centers for Disease Control, Department of Health and Human Services, 1985, Prevention and control of influenza. Recommendation of the Immunization Practices Advisory Committee, Ann. intern. Med., 103, 560, 10.7326/0003-4819-103-4-560 Ceuppens, 1982, Regulation of immunoglobulin production in pokeweed mitogen stimulated cultures of lymphocytes from young and old adults, J. Immun., 128, 2429, 10.4049/jimmunol.128.6.2429 Chandra, 1981, Immunocompetence as a functional index of nutritional status, Br. Med. Bull., 37, 89, 10.1093/oxfordjournals.bmb.a071682 Chandra, 1985, Nutritional support improves antibody responses to influenza virus vaccine in the elderly, Br. Med. J., 291, 705, 10.1136/bmj.291.6497.705 Delfraissy, 1980, Age related impairment of the in vitro antibody response in the human, Clin. Exp. Immun., 39, 208 Ehrengut, 1978, A/FM 1/47 antibody response in the aged after vaccination with A/New Jersey 76 vaccine, Lancet, 1–8061, 440, 10.1016/S0140-6736(78)91224-2 Ershler, 1985, Effect of Thyrosin alpha one on specific antibody response and susceptibility to infection in young and old mice, Int. J. Immunopharmac., 7, 465, 10.1016/0192-0561(85)90065-7 Goodwin, 1982, Immunological responses of a healthy elderly population, Clin. exp. Immun., 48, 403 Gross, 1980, Influenza vaccine in unprimed children: improved immunogenicity with few reactions following one high dose of splite product vaccine, J. Pediat., 97, 56, 10.1016/S0022-3476(80)80130-2 Gross, 1985, Effect of cancer chemotherapy on the immune responses to influenza virus vaccine: review of published studies, Rev. infect. Dis., 7, 613, 10.1093/clinids/7.5.613 Gross, 1978, Influenza vaccine in immunosuppressed children, J. Pediat., 92, 30, 10.1016/S0022-3476(78)80065-1 Hannoun, 1985, Les vaccins contre la grippe, Annls Inst. Pasteur, Paris, 136 E, 553, 10.1016/S0769-2617(85)80146-5 Hirokawa, 1977, The thymus and aging, 51 Howells, 1973, Effect of two doses of influenza vaccine in stimulating antibody in volunteers, Lancet, 1, 1436, 10.1016/S0140-6736(73)91755-8 Kim, 1985, Plaque forming cell response of human blood lymphocytes. III.-cellular basis of the reduced immune response in the elderly, Israel J. Med. Sci., 21, 317 Lange, 1979, Antibody response to influenza immunization of children with acute lymphoblastic leukemia, J. infect. Dis., 140, 402, 10.1093/infdis/140.3.402 Lerman, 1980, Antibody decline in children following A/New Jersey/76 influenza virus immunization, J. Pediat., 96, 271, 10.1016/S0022-3476(80)80823-7 Lewis, 1978, Age, thymic function and circulating thymic hormone activity, J. clin. Endocr. Metab., 47, 145, 10.1210/jcem-47-1-145 Lighthart, 1985, Subpopulations of mononuclear cells in aging: expansion of the null cell compartment and decrease in the number of T and B cells in human blood, Immunology, 55, 15 Mac Murray, 1984, Cell mediated immunity in nutritional deficiency. Progress in food and nutrition, Science, 8, 193 Moffat, 1982, Study of the immunogenicity of trivalent inactivated whole virion influenza vaccine in human volunteers, J. biol. Stand., 10, 83, 10.1016/S0092-1157(82)80029-2 Moulias, 1985, Respective roles of immune and nutritional factors in the priming of the immune response in the elderly, Mech. Ageing Devel., 31, 123, 10.1016/S0047-6374(85)80023-3 O'Leary, 1983, Evidence for a less differentiated subpopulation of lymphocytes in advanced age, Med. Ageing Devel., 21, 109, 10.1016/0047-6374(83)90068-4 Pompidou, 1985, The generation and regulation of human T lymphocytes by Imuthiol. Evidence from an in vitro differentiation induction system, Int. J. Immunopharmac., 7, 561, 10.1016/0192-0561(85)90077-3 Potter, 1977, Dose response relationship after immunization of volunteers with a new surface antigen absorbed influenza virus vaccine, J. infect. Dis., 135, 423, 10.1093/infdis/135.3.423 Renoux, 1982, Immunopharmacologie et pharmacologie du diethydithiocarbamate de sodium (DTC), J. Pharmac., Paris, 13, 95 Renoux, 1983, DTC, a T cell specific agent in nu/nu mice, 171 Renoux, 1980, Induction of differentiation of human null cells into T lymphocytes by the serum of mice treated with sodium diethyldithiocarbamate, J. Immunopharmac., 2, 49, 10.3109/08923978009026387 Sanhadji, 1985, Imuthiol. (DTC) an agent inducing T cell characteristics on to human prothymocytes, Int. J. Immunopharmac., 7, 315, 10.1016/0192-0561(85)90101-8 Schaffer, 1979, The influence of chemotherapy on response of patients with hematologic malignancies to influenza vaccine, Cancer, 43, 25, 10.1002/1097-0142(197901)43:1<25::AID-CNCR2820430103>3.0.CO;2-Q Sheth, 1979, Hemagglutination inhibiting antibodies in vaccinated children with renal disease, J. Am. Med. Assoc., 1752, 10.1001/jama.1979.03300160032021 Thompson, 1984, The immune status of healthy centenarians, J. Am. Geriat. Soc., 32, 274, 10.1111/j.1532-5415.1984.tb02021.x Wright, 1980, Comparison of influenza B/Hong-Kong virus infections among infants, children and young adults, J. infect. Dis., 141, 430, 10.1093/infdis/141.4.430