Influence of pyridoxal 5′-phosphate alone and in combination with vigabatrin on brain GABA measured by 1H-NMR-spectroscopy

Battaglioli, 1990, Stimulation of synaptosomal gamma-aminobutyric acid synthesis by glutamate and by glutamine, J. Neurochem., 54, 1179, 10.1111/j.1471-4159.1990.tb01946.x Battistin, 1984, Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities, Neurochem. Res., 9, 225, 10.1007/BF00964170 Behar, 1994, Analysis of macromolecule resonance in 1H NMR spectra of human brain, Magn. Reson. Med., 32, 294, 10.1002/mrm.1910320304 Blindermann, 1977, Purification of the glutamate decarboxylase from human brain, C. R. Acad. Sci. Hebd. Seances Acad. Sci. D, 285, 1079 Burger, 1991, GABA and glycine in synaptic vesicles, Neuron, 7, 287, 10.1016/0896-6273(91)90267-4 Duc, 1998, Quantitative 1H MRS of the human brain in vivo based on stimulation phantom calibration strategy, Magn. Reson. Med., 39, 491, 10.1002/mrm.1910390320 Erecinska, 1996, Regulation of GABA level in rat brain synaptosomes, J. Neurochem., 67, 2325, 10.1046/j.1471-4159.1996.67062325.x Erlander, 1991, Two genes encode distinct glutamate decarboxylases, Neuron, 7, 91, 10.1016/0896-6273(91)90077-D Gram, 1988, Effects of valproate, vigabatrin and aminooxyacetic acid on release of endogenous and exogenous GABA from cultured neurons, Epilepsy Res., 2, 87, 10.1016/0920-1211(88)90024-1 Higuchi, 1986, Effects of carbamazepine and valproic acid on brain immunoreactive somatostatin and gamma-aminobutyric acid in amygdala-kindled rats, Eur. J. Pharmacol., 125, 169, 10.1016/0014-2999(86)90024-5 Hsu, 2000, Association of L-glutamic acid decarboxylase to the 70 KDa heat shock protein as a potential anchoring mechanism to synaptic vesicles, J. Biol. Chem., 275, 20822, 10.1074/jbc.M001403200 Hsu, 1999, Role of synaptic vesicle proton gradient and protein phosphorylation on ATP-mediated activation of membrane-associated brain glutamate decarboxylase, J. Biol. Chem., 274, 24366, 10.1074/jbc.274.34.24366 Johnson, 1987, Proton pumps and chemiosmotic coupling as a generalized mechanism for neurotransmitter and hormone transport, Ann. N. Y. Acad. Sci., 493, 162, 10.1111/j.1749-6632.1987.tb27198.x Kapetanovic, 1988, Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate and glutamine in mouse brain cortex, Biochem. Pharmacol., 37, 4445, 10.1016/0006-2952(88)90659-4 Kash, 1997, Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase, Proc. Natl. Acad. Sci., 94, 14060, 10.1073/pnas.94.25.14060 Martin, 1998, Are GAD65 and GAD67 associated with specific pools of GABA in brain, Perspect. Dev. Neurobiol., 5, 119 Maycox, 1990, Amino acid neurotransmission, TINS, 13, 83 Mueller, 2001, Effects of vigabatrin on brain GABA+/Cr signals in epileptics monitored by 1H-NMR-spectroscopy, Epilepsia, 42, 29, 10.1046/j.1528-1157.2001.077889.x Petroff, 1996, Human brain gamma-aminobutyric acid levels and seizure control following initiation of vigabatrin therapy, J. Neurochem., 67, 2399, 10.1046/j.1471-4159.1996.67062399.x Petroff, 1999, Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures, Epilepsia, 40, 958, 10.1111/j.1528-1157.1999.tb00803.x Petroff, 1999, Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy, Neurology, 40, 473, 10.1212/WNL.52.3.473 Petroff, 1998, Vigabatrin increases human brain homocarnosine and improves seizure control, Ann. Neurol., 44, 948, 10.1002/ana.410440614 Petroff, 1995, Symbiosis between in vivo and in vitro NMR spectroscopy, Magn. Reson. Imaging, 13, 1197, 10.1016/0730-725X(95)02033-P Petroff, 1998, Measuring human brain GABA in vivo, Mol. Neurobiol., 16, 97, 10.1007/BF02740605 Petroff, 1995, Initial observations on effect of vigabatrin on in vivo 1H spectroscopic measurements of gamma-aminobutyric acid, glutamate and glutamine in human brain, Epilepsia, 36, 457, 10.1111/j.1528-1157.1995.tb00486.x Petroff, 1996, Human brain GABA levels rise after initiation of vigabatrin therapy but fail to rise further with increasing dose, Neurology, 46, 1459, 10.1212/WNL.46.5.1459 Piérard, 1999, Effects of GABA-transaminase inhibition on brain and amino-acid compartmentation, Exp. Brain Res., 127, 321, 10.1007/s002210050802 Rimvall, 1992, Increased intracellular gamma-aminobutyric acid selectively lowers the level of two glutamate decarboxylase proteins in cultured GABA-ergic neurons from rat cerebral cortex, J. Neurochem., 58, 158, 10.1111/j.1471-4159.1992.tb09291.x Rimvall, 1994, The level of GAD67 protein is highly sensitive to small increases in intraneuronal gamma-aminobutyric acid levels, J. Neurochem., 62, 1375, 10.1046/j.1471-4159.1994.62041375.x Rimvall, 1993, Effects of increased gamma-aminobutyric acid levels on GAD67 protein and mRNA levels in rat cerebral cortex, J. Neurochem., 60, 714, 10.1111/j.1471-4159.1993.tb03206.x Rowley, 1995, Differential effects of phenytoin and sodium valproate on seizure-induced changes in gamma-aminobutyric acid and glutamate release in vivo, Eur. J. Pharmacol., 294, 541, 10.1016/0014-2999(95)00589-7 Sherif, 1992, Studies on gamma-aminobutyrate aminotransferase (GABA-T) activities in human and rodent brain homogenates, Arch. Int. Physiol. Biochem. Biophys., 100, 361, 10.3109/13813459209000727 Soghomonian, 1998, Two isoforms of glutamate decarboxylase, Trends Pharmacol. Sci., 19, 500, 10.1016/S0165-6147(98)01270-X Toney, 1995, Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities, Prot. Sci., 4, 2366, 10.1002/pro.5560041115 Weber, 1997, Detection of hidden metabolites by localized proton magnetic resonance spectroscopy in vivo, Technol. Health Care, 5, 471, 10.3233/THC-1997-5606 Weber, 1999, Effects of vigabatrin intake on brain GABA activity as monitored by spectrally edited magnetic resonance spectroscopy and positron emission topography, Magn. Reson. Imaging, 17, 417, 10.1016/S0730-725X(98)00184-2 White, 1978, GABA-transaminases of human brain and peripheral tissues—Kinetic and molecular properties, J. Neurochem., 31, 41, 10.1111/j.1471-4159.1978.tb12430.x