Influence of insulin and of insulin resistance on platelet and vascular smooth muscle cell function

Anfossi, 1993, Insulin increases endothelin-1 production by vascular smooth muscle cells derived from human microvessels, vol. 12, 272

Anfossi, 1993, Insulin influences immunoreactive endothelin release by human vascular smooth muscle cells, Metabolism, 42, 1081, 10.1016/0026-0495(93)90261-L

Anfossi, 1996, Insulin exerts opposite effects on platelet function at physiological and supraphysiological concentrations, Thrombosis Research, 82, 57, 10.1016/0049-3848(96)00051-5

Anfossi, 1993, Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the anti-aggregating effects of the stable prostacyclin analogue Iloprost, Prostaglandins, Leukotrienes and Essential Fatty Acids, 49, 839, 10.1016/0952-3278(93)90207-D

Anfossi, 1994, Effect of forskolin and organic nitrates on aggregation and intracellular cyclic nucleotide content in human platelets, General Pharmacology, 25, 1093, 10.1016/0306-3623(94)90123-6

Anfossi, 1995, Glyceryl trinitrate enhances the adenosine induced inhibition of platelet responses: a mechanism potentially involved in the in vivo antiaggregating effects of organic nitrates, Clinical and Experimental Pharmacology and Physiology, 22, 803, 10.1111/j.1440-1681.1995.tb01939.x

Anfossi, 1998, Impaired platelet sensitivity to the anti-aggregating effects of adenosine in obesity and obese non-insulin-dependent diabetes mellitus, vol. 14, 184

Anfossi, 1998, Platelet resistance to nitrates in obesity and obese NIDDM and normal platelet sensitivity to both insulin and nitrates in lean NIDDM, Diabetes Care, 21, 121, 10.2337/diacare.21.1.121

Anfossi, 1999, l-Arginine modulates aggregation and intracellular cyclic-3′,5′-guanosine monophosphate levels in human platelets: direct effect and interplay with antioxidative thiol agent, Thrombosis Research, 94, 307, 10.1016/S0049-3848(99)00011-0

Cavalot, 1997, Influence of protamine on adhesion, chemotaxis and proliferation of human vascular smooth muscle cells, Diabetologia, 40, 67, 10.1007/s001250050644

Hsueh, 1999, Insulin signaling in the arterial wall, American Journal of Cardiology, 84, 21J, 10.1016/S0002-9149(99)00353-7

Jiang, 1999, Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats., Journal of Clinical Investigation, 104, 447, 10.1172/JCI5971

Laasko, 1992, Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM, Diabetes, 41, 1076, 10.2337/diabetes.41.9.1076

Maurice, 1990, Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP, Molecular Pharmacology, 37, 671

Mittal, 1977, Formation of adenosine 3′,5′-monophosphate by preparations of guanylate cyclase from rat liver and other tissues, Journal of Biological Chemistry, 252, 3136, 10.1016/S0021-9258(17)40362-0

Murer, 1994, Insulin increases the aggregation response of human platelets to ADP, Thrombosis Research, 73, 69, 10.1016/0049-3848(94)90055-8

Scherrer, 1994, Nitric oxide release accounts for insulin's vascular effects in humans, Journal of Clinical Investigation, 94, 2511, 10.1172/JCI117621

Schini, 1991, Interleukin-1 beta induces the production of an l-arginine-derived relaxing factor from cultured smooth muscle cells from aorta, Biochemical and Biophysical Research Communications, 176, 114, 10.1016/0006-291X(91)90897-G

Steinberg, 1994, Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release, Journal of Clinical Investigation, 94, 1172, 10.1172/JCI117433

Trovati, 1998, Insulin, insulin resistance and platelet function: similarities with insulin effects on cultured vascular smooth muscle cells, Diabetologia, 41, 609, 10.1007/s001250050958

Trovati, 1988, Insulin directly reduces platelet sensitivity to aggregating agents: studies in vitro and in vivo, Diabetes, 37, 780, 10.2337/diabetes.37.6.780

Trovati, 1986, Studies on mechanisms involved in hypoglycaemia-induced platelet activation, Diabetes, 35, 818, 10.2337/diabetes.35.7.818

Trovati, 1997, Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide, increases platelet concentrations of both guanosine-3′,5′-cyclic monophosphate and adenosine-3′,5′-cyclic monophosphate, Diabetes, 46, 742, 10.2337/diabetes.46.5.742

Trovati, 1989, Insulin reduces platelet sensitivity to platelet activating factor in washed human platelets resuspended in a calcium-free medium, Diabetes, Nutrition and Metabolism, 2, 151

Trovati, 1995, Insulin increases cyclic nucleotide content in human vascular smooth muscle cells: a mechanism potentially involved in insulin-induced modulation of vascular tone, Diabetologia, 38, 936, 10.1007/BF00400582

Trovati, 1996, Studies on the influence of insulin on cyclic adenosine monophosphate in human vascular smooth muscle cells: dependence on cyclic guanosine monophosphate and modulation of catecholamine effects, Diabetologia, 39, 1156, 10.1007/BF02658501

Trovati, 1999, Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3′:5′-cyclic monophosphate and adenosine 3′:5′-cyclic monophosphate concentrations, Diabetologia, 42, 831, 10.1007/s001250051234

Trovati, 1994, Insulin increases guanosine-3′-5′-cyclic monophosphate in human platelets: a mechanism involved in the insulin anti-aggregating effect, Diabetes, 43, 1015, 10.2337/diabetes.43.8.1015

Trovati, 1996, The insulin-induced increase of guanosine-3′,5′-cyclic monophosphate in human platelets is mediated by nitric oxide, Diabetes, 45, 768, 10.2337/diabetes.45.6.768

Trovati, 1995, Impaired insulin-induced platelet anti-aggregating effect in obesity and in obese NIDDM patients, Diabetes, 44, 1318, 10.2337/diabetes.44.11.1318

Vollenweider, 1994, Impaired insulin-induced sympathetic neural activation and vasodilation in skeletal muscle in obese humans, Journal of Clinical Investigation, 93, 2365, 10.1172/JCI117242

Zeng, 1996, Insulin-stimulated production of nitric oxide is inhibited by wortmannin: direct measurement in vascular endothelial cells, Journal of Clinical Investigation, 98, 894, 10.1172/JCI118871

Zeng, 2000, Roles for insulin receptor, PI3-kinase, and Akt in insulin signaling pathways related to production of nitric oxide in human vascular endothelial cells, Circulation, 101, 1539, 10.1161/01.CIR.101.13.1539