Influence of environmental temperature on energy balance, diet-induced thermogenesis and brown fat activity in ‘cafeteria’-fed rats

British Journal of Nutrition - Tập 56 Số 1 - Trang 123-129 - 1986
Nancy J. Rothwell1, Michael J. Stock2
1Office of the President & Vice Chancellor
2Department of Physiology, St George's Hospital Medical School, Tooting, London, SW17 ORE

Tóm tắt

1. Young male rats were fed on a pelleted stock diet or a variety of palatable food items (‘cafeteria’ diet) and housed at 24° or 29°.2. ‘Cafeteria’ feeding at the lower temperature stimulated energy intake, gain and expenditure, but reduced energetic efficiency such that over 70% of the excess intake was expended.3. Housing at 29° suppressed intake and expenditure in animals on both diets, but to a greater extent in ‘cafeteria’-fed rats and energetic efficiency was greater than control values at this higher temperature.4. The thermogenic capacity of brown fat (mitochondrial purine nucleotide binding) was increased by ‘cafeteria’ feeding, but was suppressed in animals kept at 29°.5. The results demonstrate that diet-induced thermogenesis is inhibited by high environmental temperatures.

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Tài liệu tham khảo

10.1172/JCI110541

Rothwell, 1984, Recent Advances in Physiology, 10, 349

10.1007/BF00584784

10.1139/y80-130

Tulp, 1981, International Journal of Obesity, 5, 579

10.1146/annurev.nu.05.070185.000441

Brobeck, 1948, Yale Journal of Biological Medicine, 20, 545

10.1007/978-94-011-6032-2_7

10.1113/expphysiol.1982.sp002634

10.1113/jphysiol.1982.sp014270

10.2170/jjphysiol.34.939

10.1152/physrev.1984.64.1.1

10.1079/BJN19820058

10.1038/295323a0

10.1016/0026-0495(85)90214-8

Hamilton, 1967, Handbook of Physiology, Section 6, Alimentary Canal, 1, 303

Rothwell, 1982, international Journal of Obesity, 6, 53

10.1007/BF00584574

10.1079/BJN19780142

10.1079/BJN19840044

10.1038/281031a0