Influence of dose-averaged linear energy transfer on tumour control after carbon-ion radiation therapy for pancreatic cancer

Clinical and Translational Radiation Oncology - Tập 21 - Trang 19-24 - 2020
Yasuhito Hagiwara1,2, Tapesh Bhattacharyya1, Naruhiro Matsufuji3, Yuka Isozaki1, Hirotoshi Takiyama1, Kenji Nemoto2, Hiroshi Tsuji1, Shigeru Yamada1,4
1Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology, Anagawa 4-9-1, Inage-ku, 263-8555 Chiba, Japan
2Department of Radiation Oncology, Faculty of Medicine, Yamagata University, Iida-nishi 2-2-2, Yamagata-shi, 990-9585 Yamagata, Japan
3Department of Accelerator and Medical Physics, Research Center for Particle Therapy, National Institute of Radiological Sciences, Anagawa 4-9-1, Inage-ku, 263-8555 Chiba, Japan
4Department of Charged Particle Therapy Research, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Anagawa 4-9-1, Inage-ku, 263-8555 Chiba, Japan

Tài liệu tham khảo

Siegel, 2015, Cancer statistics, C.A. Cancer J Clin, 2015, 5, 10.3322/caac.21254 Yamamoto, 1998, Japan pancreatic cancer registry: Current status, Pancreas, 16, 238, 10.1097/00006676-199804000-00006 Ueno, 2009, A randomised phase III trial comparing gemcitabine with surgery-only in patients with resected pancreatic cancer: Japanese Study Group of Adjuvant Therapy for Pancreatic Cancer, Br J Cancer, 101, 908, 10.1038/sj.bjc.6605256 Loehrer, 2011, Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group Trial, J Clin Oncol, 29, 4105, 10.1200/JCO.2011.34.8904 Klaassen, 1985, Treatment of locally unresectable cancer of the stomach and pancreas: a randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil–an Eastern Cooperative Oncology Group study, J Clin Oncol., 3, 373, 10.1200/JCO.1985.3.3.373 Gastrointestinal Tumor Study Group, 1988, Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. Gastrointestinal Tumor Study Group, J Natl Cancer Inst, 80, 751, 10.1093/jnci/80.10.751 Krishnan, 2016, Focal radiation therapy dose escalation improves overall survival in locally advanced pancreatic cancer patients receiving induction chemotherapy and consolidative chemoradiation, Int J Radiat Oncol Biol Phys, 94, 755, 10.1016/j.ijrobp.2015.12.003 Mahadevan, 2010, Stereotactic body radiotherapy and gemcitabine for locally advanced pancreatic cancer, Int J Radiat Oncol Biol Phys, 78, 735, 10.1016/j.ijrobp.2009.08.046 Sachsman, 2014, Proton therapy and concomitant capecitabine for non-metastatic unresectable pancreatic adenocarcinoma, Int J Particle Ther, 1, 692, 10.14338/IJPT.14-00006.1 Grassberger, 2011, Variations in linear energy transfer within clinical proton therapy fields and the potential for biological treatment planning, Int J Radiat Oncol Biol Phys, 80, 1559, 10.1016/j.ijrobp.2010.10.027 Koong, 2000, Pancreatic tumors show high levels of hypoxia, Int J Radiat Oncol Biol Phys, 48, 919, 10.1016/S0360-3016(00)00803-8 Kanai, 1999, Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy, Int J Radiat Oncol Biol Phys, 44, 201, 10.1016/S0360-3016(98)00544-6 Kawashiro, 2018, Multi-institutional Study of carbon-ion Radiotherapy for Locally Advanced Pancreatic Cancer: Japan carbon-ion Radiation Oncology Study Group (J-CROS) Study 1403 Pancreas, Int J Radiat Oncol Biol Phys, 101, 1212, 10.1016/j.ijrobp.2018.04.057 Bassler, 2010, Dose- and LET-painting with particle therapy, Acta Oncol., 49, 1170, 10.3109/0284186X.2010.510640 Bassler, 2014, LET-painting increases tumour control probability in hypoxic tumours, Acta Oncol, 53, 25, 10.3109/0284186X.2013.832835 Tinganelli, 2015, Kill-painting of hypoxic tumours in charged particle therapy, Sci Rep, 5, 17016, 10.1038/srep17016 United States Department of Health and Human Services. Common Terminology Criteria for Adverse Events v4.0 NIH publication 2009 https://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03/Archive/CTCAE_4.0_2009-05-29_QuickReference_8.5x11.pdf. [accessed14 September 2019]. Shinoto, 2013, Phase 1 trial of preoperative, short-course carbon-ion radiotherapy for patients with resectable pancreatic cancer, Cancer, 119, 45, 10.1002/cncr.27723 Karger, 2017, RBE and related modeling in carbon-ion therapy, Phys Med Biol, 63, 01TR02, 10.1088/1361-6560/aa9102 Kanematsu, 2018, Estimation of linear energy transfer distribution for broad-beam carbon-ion radiotherapy at the National Institute of Radiological Sciences, Japan. Radiol Phys Technol., 11, 242, 10.1007/s12194-018-0444-7 Shinoto, 2016, Carbon ion radiation therapy with concurrent gemcitabine for patients with locally advanced pancreatic cancer, Int J Radiat Oncol Biol Phys., 95, 498, 10.1016/j.ijrobp.2015.12.362