Influence of Nd:YAG laser power density and coaxial CO2 on the gastric wall

Lasers in Surgery and Medicine - Tập 4 Số 3 - Trang 247-259 - 1984
Stephen N. Joffe1, I.A. MacLeod2, Supriya Rao3
1Department of Surgery, University of Cincinnati Medical Center, Cincinnati, Ohio
2Glasgow Royal Infirmary, Glasgow, Scotland
3Department of Public Health, Pathological Laboratories, Doha, Qatar

Tóm tắt

AbstractA detailed understanding is required of the effect of Nd: YAG power density and coaxial CO2 on tissue necrosis in both the acute and healing situation. Lesions were produced by varying peak powers at eight increments of 10 W from 40–110 W/sec for a time duration of 1 sec with and without coaxial CO2 on the rabbit (n=16) stomach. Surface areas and careful histological examinations were performed at 2 hr and 4 days. In further experiments, a total incident energy of 60 or 120 J with varying peak powers from 30‐120 W/sec were applied at a 1‐cm distance. The lesion surface area at 1 cm was 21.7 mm2 compared to 12 mm2when the fiber tip was held 2 cm away (p < 0.05). Coaxial CO2 at 1 cm reduced the surface area to 10 mm2 (p < 0.001). There was a positive correlation between surface areas and the incidental power (r = 0.86, p < 0.01). There was no significant difference in the mean surface area of lesions at 2 hr compared to those at 4 days, nor was there a correlation between the increasing peak powers with the constant incident energy. Histological features were those of coagulative necrosis (81 %)‐with minimal ulceration (1.6%) at 2 hr with ulceration increasing to 22% at 4 days. These results have helped in planning a safe and effective Nd:YAG photocoagulation study in patients in order to obtain maximum hemostasis with minimal tissue injury.

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Lasers in Surgery and Medicine

Tập 4 Số 3

247-259

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