Influência da Diabetes Mellitus no Desenvolvimento da Doença Periodontal

Diana Correia1, Gil Alcoforado2, Paulo Mascarenhas3
1Médica Dentista Militar no Serviço de Estomatologia e Medicina Dentária do HMP
2Professor Catedrático da FMDUL e regente da cadeira de Periodontologia. Director do Curso de Especialização em Periodontologia da FMDUL
3Mestre em Periodontologia e Docente da disciplina de Periodontologia e do Mestrado na Universidade de Lisboa

Tài liệu tham khảo

Cianciola, 1982, Prevalence of periodontal disease in insulin dependent diabetes mellitus (juvenile diabetes), JADA, 104, 653 Abdulrazzaq, 2008, Diabetes Mellitus its management and complications, International Dental Journal, 58, 231, 10.1111/j.1875-595X.2008.tb00202.x 1999, Diabetes and periodontal Diseases, Journal of Periodontology, 70, 935, 10.1902/jop.1999.70.8.935 Souhami, 2002 Socransky, 1992, The bacterial etiology of destructive periodontal djsease: Current concepts, J Periodontal, 21, 720 Iacopino, 2000, Pathophysioloaical Relationships Between Periodontitis and Systemic Disease: Recent Concepts Involving Serum lipids, J Periodontol, 71, 1375, 10.1902/jop.2000.71.8.1375 Liljenberg, 1994, Some microbiological, histopathological and immunohistochemical characteristics of progressive periodontal disease, J Clin Periodontal, 21, 720, 10.1111/j.1600-051X.1994.tb00793.x Loos, 2005, Systemic Markers of Inflammation in Periodontitis, J Periodontol, 76, 2106, 10.1902/jop.2005.76.11-S.2106 Matilla, 1995, Dental infection and the risk of new coronary events: prospective study of patients with documented coronary artery disease, Ainical Infectious Disease, 20, 588, 10.1093/clinids/20.3.588 Lindhe, 2005, Tratado de Periodontia Clínica e Implantologia Oral, Guanabara Koogan Lieff, 2000, Periodontitis and preterm Iow birthweight jsk in pregnant women, Journal of Dental Research, 79, 608 Lindhe, 2005, Tratado de Periodontia Clínica e Implantologia Oral, Guanabara Koogan Scannapieco, 1999, Role of oral bactéria in respiratory infection, Journal of Periodontology, 70, 793, 10.1902/jop.1999.70.7.793 Lindhe, 2005 Syrajanen, 1989, Dental infections in association with cerebral infarction in young and middle-aged men, J Intern Med, 225, 179, 10.1111/j.1365-2796.1989.tb00060.x Iacopino, 2000, Pathophysiological Relationships Between Periodontitis and Systemic Disease: Recent Concepts Involving Serum lipids, J Periodontol, 71, 1375, 10.1902/jop.2000.71.8.1375 Mealey, 2006, Diabetes Mellitus and Periodontal Diseases –AAP-Commissioned Review, J Periodontal, 77, 1289, 10.1902/jop.2006.050459 Preshaw, 2008, Diabetes and periodontal disease, International Dental Journal, 58, 237, 10.1111/j.1875-595X.2008.tb00203.x Grossi, 1998, Periodontal Disease and Diabetes Mellitus: A Two-Way Relationship, Ann Periodontol, 3, 51, 10.1902/annals.1998.3.1.51 Soskolne, 2001, The Relationship Between Periodontal Diseases and Diabetes: an Overview, Ann Periodontol, 6, 91, 10.1902/annals.2001.6.1.91 Taylor, 2001, Bidirectional interrelationships between Diabetes and periodontal diseases: An epidemiologic perspective, Ann Periodontol, 6, 99, 10.1902/annals.2001.6.1.99 Kasper, 2006 Lindhe, 2005 Nerup, 1987, The HLA-IDDM association: Implications for etiology and pathogenesis of IDDM, Diabetes Metab Rev, 3, 779, 10.1002/dmr.5610030309 Soskolne, 2001, The Relationship Between Periodontal Diseases and Diabetes: an Overview, Ann Periodontol, 6, 91, 10.1902/annals.2001.6.1.91 Khader, 2006, Periodontal status of diabetics compared with nondiabetics: a meta-analysis, Journal of Diabetes and its Complications, 20, 59, 10.1016/j.jdiacomp.2005.05.006 Iacopino, 2001, Pathophysioloaical Relationships Between Periodontitis and Systemic Disease: Recent Concepts Involving Serum lipids, J Periodontol, 71, 1375, 10.1902/jop.2000.71.8.1375 Garg, 1992, Lipid-lowering therapy and macrovascular disease in diabetes mellitus, Diabetes, 41 1998, Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33), Lancet, 352, 837, 10.1016/S0140-6736(98)07019-6 Haraszthy, 2000, Identification of Periodontal Pathogens in Atheromatous Paques, J Periodontal, 71, 1554, 10.1902/jop.2000.71.10.1554 Cutler, 1999, Association between periodontitis and hyperlipidemia: Cause or effect?, J Periodontal, 70, 1429, 10.1902/jop.1999.70.12.1429 Salvi, 2005, Experimental gingivitis in type I diabetics a controlled clinical and microbiological study, J Clin Periodontol, 32, 31 Caton, 2001, Sub antimicrobial dose doxycycline as an adjunct to scaling and root planning: post–treatment effects, J Clin Periodontol, 28, 782, 10.1034/j.1600-051X.2001.280810.x Doxey, 1998, Diabetes-induced impairment of macrophage cytokine release in a rat model: Potential role of Iserurn lipids, Life Sci, 63, 1127, 10.1016/S0024-3205(98)00374-9 Chu, 1999, In vitro alteration of macrophage phenotype and function by serum lipids, Cell Tiss Res, 296, 331, 10.1007/s004410051293 Iacopino, 2001, Pathophysioloaical Relationships Between Periodontitis and Systemic Disease: Recent Concepts Involving Serum lipids, J Periodontol, 71, 1375, 10.1902/jop.2000.71.8.1375 Andersen, 2007, Relationship Between Periodontitis and Diabetes: Lessons From Rodent Studies, J Periodontol, 78, 1264, 10.1902/jop.2007.060491 McMullen, 1981, Neutrophil Chemotaxis in Individuals with Advanced Periodontal Disease and a Genetic Predisposition to Diabetes Mellitus, J Periodontology, 52, 167, 10.1902/jop.1981.52.4.167 Gonçalves, 2008, The effect uf nun-surgical periodontal therapy on peroxidase activity in diabetic patients: a case-conlro pilot study, J Clin Periodontol, 35, 799, 10.1111/j.1600-051X.2008.01289.x Alpagot, 2001, Crevicular fluid elastase levels in relation to periodontitis and metabolic control of diabetes, J Periodont Res, 36, 169, 10.1034/j.1600-0765.2001.360305.x Drobny, 1984, Insulin receptors in acute infection: A study of factors conferring insuIin resistance, J clin Endocrinol Metab, 58, 710, 10.1210/jcem-58-4-710 Drobny, 1999, In Academy Reports. Position Paper. Diabetes and periodontal Diseases, Journal of Periodontology, 70, 935, 10.1902/jop.1999.70.8.935 D’Aiuto, 2005, Short-term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol, J Dent Res, 84, 269, 10.1177/154405910508400312 Nishimura, 1998, Periodontal disease as a complication of diabetes mellitus, Ann Periodontol, 3, 20, 10.1902/annals.1998.3.1.20 Duarte, 2007, Overexpression of interleukin- 1 beta and interleukin-6 may play an important role in periodontal breakdown in type 2 diabetic patients, J Periodont Res, 42, 377, 10.1111/j.1600-0765.2006.00961.x Wedrychowicz, 2004, Wedrychowicz A.Interleukin-6 (IL-6) and IGFGFBP system in children and adolescents with type 1 diabetes mellitus, Experimental and Clinical Endocrinology & Diabetes, 112, 435, 10.1055/s-2004-821189 Sogan, 2006 Raunio, 2009, IL-6-174 genotype associated with the extent of periodontal disease in type 1 diabetic subjects, J Clin Periodontol, 36, 11, 10.1111/j.1600-051X.2008.01344.x Mathur, 1996, Interleukin I-alpha, interleucin 8 and interferon alpha levels in gingival crevicular fluid, J Periodont Res, 31, 489, 10.1111/j.1600-0765.1996.tb01414.x Atish T., 2006, Modulating TNF-α signaling with natural products, Drug Discovery Today, 11, 15 Engebretson, 2007, Plasma levels of tumor necrosis factor-alfa in patients with chronic periodontitis and type 2 diabetes, J Clin Periodontal, 34, 18, 10.1111/j.1600-051X.2006.01017.x Vassalli, 1992, The pathophysiology of tumor necrosis factors, Annual Revues in Immunology, 10, 411, 10.1146/annurev.iy.10.040192.002211 Salvi, 1997, Monocytic TNF alfa secretion patterns in IDDM patients with periodontal diseases, J Clin Periodontol, 24, 8, 10.1111/j.1600-051X.1997.tb01178.x Pushkareva, 1995, Ceramide: an endogenous regulator of apoptosis and growth suppression, Imunology Today, 16, 294, 10.1016/0167-5699(95)80184-7 Salvi, 1997, Monocytic TNF alfa secretion patterns in IDDM patients with periodontal diseases, J Clin Periodontol, 24, 8, 10.1111/j.1600-051X.1997.tb01178.x Matsumoto, 2009, Effect of antimicrobial periodontal treatment and maintenance on serum adiponectin in Type 2 Diabetes Mellitus, J Clin Periodontol, 36, 142, 10.1111/j.1600-051X.2008.01359.x Karima, 2005, Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis, J Leukoc Biol, 78, 862, 10.1189/jlb.1004583 King, 2008, The Role of Inflammatory Cytokines in Diabetes and Its Complications, J Periodontol, 79, 1527, 10.1902/jop.2008.080246 Gorus, 1998, Increased prevalence of abnormal immunoglobulin M, G, and A concentrations at clinical onset of insulin-dependent diabetes mellitus: a registry-based study, The Belgian Diabetes Registry, 16, 50 Moreno, 2001, Hypersialylated macromolecular serum immunoglobulin Al in type 2 diabetes mellitus, Clinical Biochemistry, 34, 35, 10.1016/S0009-9120(00)00192-2 Gugliucci, 2000, Glycation as the glucose link to diabetic complications, JAOA, 100, 621 Gomes, 2006, Levels of immunoglobulin Al and Messenger RNA for interferon y and tumor necrosis factor a in total saliva from patients with diabetes mellitus type 2 with chronic periodontal disease, J Periodont Res, 41, 177, 10.1111/j.1600-0765.2005.00851.x Sternlicht, 2001, How matrixmetalloproteinases regulate cell behavior, Annu Rev Cell Dev Biol, 17, 463, 10.1146/annurev.cellbio.17.1.463 Silva, 2008, The influence of type I diabetes mellitus on the expression and activity of Gelatinases (matrix metalloproteinases-2 and I -9) in induced periodontal disease, J Periodont Res, 43, 48 2005, Diagnosis and classification of diabetes mellitus. Position statement, Diabetes Care, 29, S37 Trevonen, 2007, Polymorphisms in the CD14 and IL-6 genes associated with periodontal disease, J Clin Periodontal, 34, 377, 10.1111/j.1600-051X.2007.01067.x Alley, 1993, HLA-D and T Lymphocyte reactivity to specific periodontal pathogens in type 1 diabetic periodontitis, J Periodontal, 64, 974, 10.1902/jop.1993.64.10.974 Mealey, 2003, Hormonal-influences: effects of diabetes mellitus. And. endogenous female sex steroid c hormones on the· periodontium, Periodontology, 32, 59, 10.1046/j.0906-6713.2002.03206.x Schmidt, 1999, Activation of receptor for advanced glycation end products. A mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis, Circ Res, 84, 489, 10.1161/01.RES.84.5.489 Wei, 2004, The investiation of glutathione peroxidase, lactoferrin, myeloperoxidase and interleukin-1 beta in gingival crevicular fluid: implications for oxidative stress in human periodontal diseases, Journal Of Periodontal Research, 39, 287, 10.1111/j.1600-0765.2004.00744.x Lalla, 2007, Diabetes-related parameters and periodontal conditions in children, J Periodont Res, 42, 345, 10.1111/j.1600-0765.2006.00955.x Hussain, 1996, Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM, Diabetologia, 391, 60, 10.1007/BF00400414 Lanza, 1998, Clinical manifestations of myeloperoxidase deficiency, Journal of Molecular Medicine, 76, 676, 10.1007/s001090050267 Offenbacher, 1993, Modulation of host PGE2 secretion as a determinant of periodontal disease expression, Journal of Periodontology, 64, 432, 10.1902/jop.1993.64.5s.432 Dyke, 2008, The Management of Inflammation in Periodontal Disease, J Periodontol, 79, 1601, 10.1902/jop.2008.080173 Sbordone, 1995, Periodontal status and selected cultivable anaerobic microflora of insulin-dependent juvenile diabetics, J Periodontol, 66, 452, 10.1902/jop.1995.66.6.452 Mandell, 1992, Microbiology of healthy and diseased periodontal sites in poorly controlled insulin dependent diabetics, Journal of Periodontology, 63, 274, 10.1902/jop.1992.63.4.274 SastroWijoto, 1990, Improved metabolic control, clinical periodontal status and subgingivaI microbiologyin insulin·dependent diabetes mellitus. Prospective study, J CIin Penodontol, 17, 233 Monnier, 1996, The mechanism of collagen cross-linking in diabetes. A puzzle nearing resolution, Diabetes, 45, 67, 10.2337/diab.45.3.S67 Mealey, 2006, Periodontal disease and diabetes: A two-way street, J Am Dent Assoc, 137, 26S, 10.14219/jada.archive.2006.0404 Golub, 1998, Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms, Adv Dent Res, 12, 12, 10.1177/08959374980120010501 Mealey, 2006, Periodontal disease and diabetes: A two-way street, J Am Dent Assoc, 137, 26, 10.14219/jada.archive.2006.0404 Wang, 2002, Age-related changes in the collagen network and toughness of bone, Bone, 31, 1, 10.1016/S8756-3282(01)00697-4 Leonardi, 2006, Immunolocalization of CD44s in human teeth, Acta Histochemica, 108, 425, 10.1016/j.acthis.2006.06.006 Aruna D., 2001, C-Reactive Protein, Interleukin 6, and Risk of Developing type 2 Diabetes Mellitus, JAMA, 286, 327, 10.1001/jama.286.3.327 Bourguignon, 2006, Hyaluronan-CD44 interaction stimulates keratinocyte differentiation, lamellar body formalion/secretion, and penneability barrier homeostasis, Journal of Investigative Dermatology, 126, 1356, 10.1038/sj.jid.5700260 Seppala, 1997, Morphometric analysis of cellular and vascular changes in gingival connective tissue in long-term insulin-dependent diabetes, J Periodontol, 68, 1237, 10.1902/jop.1997.68.12.1237 Unlu, 2003, Expression of vascular endothelial growth factor in human periodontal tissues: comparison of healthy and diabetic patients, Journal of Periodontology, 74, 181, 10.1902/jop.2003.74.2.181 Schmidt, 1996, Advanced glycation end products (AGEs) induce oxidant stress in the gingival: A potential mechanism underlying accelerated periodontal disease associated with diabetes, J Periodontal Res, 31, 508, 10.1111/j.1600-0765.1996.tb01417.x Esposito, 2002, Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: Role of oxidative stress, Circulation, 106, 2067, 10.1161/01.CIR.0000034509.14906.AE Sakallioglu, 2007, Vascular endothelial growth factor (VEGF) levels of gingivaI and gingival crevicular fluid in diabetic and systemically healthy periodontitis patients, Clinical Oral Investigations, 11, 115, 10.1007/s00784-006-0097-5 Lucarini, 2009, Involvement of vascular endothelial growth factor, CD44 and CD133 in periodontal disease and diabetes: an Immunohistochemical study, J Clin Periodontol, 36, 3, 10.1111/j.1600-051X.2008.01338.x Yin, 1997, AC 133, a novel marker for human hematopoietic stem and progenitor cells, Blood, 90, 5002, 10.1182/blood.V90.12.5002 Lucarini, 2009, Lo Muzio et al. Involvement of vascular endothelial growth factor, CD44 and CD133 in periodontal disease and diabetes: an Immunohistochemical study, J Clin Periodontol, 36, 3, 10.1111/j.1600-051X.2008.01338.x Rees, 2000, Periodontal management of the patient with diabetes mellitus, Periodontology, 23, 63, 10.1034/j.1600-0757.2000.2230105.x Darre, 2008, Efficacy of periodontal treatment on glycaemic control in diabetic patients: A meta- -analysis of interventional studies, Diabetes & Metabolism, 34, 491, 10.1016/j.diabet.2008.03.006 Golub, 1983, Minocycline reduces gingival collagenolytic activity during Diabetes, Journal of Periodontal Research, 18, 10.1111/j.1600-0765.1983.tb00388.x