Inflammatory pathways in the mechanism of parturition

Jane E. Norman1, Shrikant S. Bollapragada1, Mei Yuan1, Scott M. Nelson1
1University of Glasgow Division of Developmental Medicine, Glasgow Royal Infirmary, Queen Elizabeth Building, 10 Alexandra Parade, Glasgow, G31 2ER, UK

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Tài liệu tham khảo

Preterm birth in Scotland. [ http://bmj.bmjjournals.com/cgi/eletters/332/7547/937#132366 ]

Thomson A, Telfer J, Young A, Campbell S, Stewart C, Cameron I, Greer I, Norman J: Leukocytes infiltrate the myometrium during human parturtion: further evidence that labour is an inflammatory process. Human Reproduction. 1999, 14: 229-236. 10.1093/humrep/14.1.229.

Osman I, Young A, Ledingham M, Thomson A, Jordan F, Greer I, Norman J: Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term. Molecular Human Reproduction. 2003, 9: 41-45. 10.1093/molehr/gag001.

Young A, Jordan F, Ledingham M, Thomson A, Norman J, Greer I: Quantification of pro-inflammatory cytokines in myometrium, cervix and fetal membranes during human parturition. Journal of the Society of Gynecologic Investigation. 2002, 9: 137A-10.1016/S1071-5576(02)00142-9.

Ledingham MA, Thomson AJ, Jordan F, Young A, Crawford M, Norman JE: Cell adhesion molecule expression in cervix and myometrium during pregnancy and parturition. Obstet Gynecol. 2001, 97: 235-242. 10.1016/S0029-7844(00)01126-1.

Tribe RM, Moriarty P, Dalrymple A, Hassoni AA, Poston L: Interleukin-1beta induces calcium transients and enhances basal and store operated calcium entry in human myometrial smooth muscle. Biol Reprod. 2003, 68 (5): 1842-1849. 10.1095/biolreprod.102.011403.

Oger S, Mehats C, Dallot E, Ferre F, Leroy MJ: Interleukin-1beta induces phosphodiesterase 4B2 expression in human myometrial cells through a prostaglandin E2- and cyclic adenosine 3',5'-monophosphate-dependent pathway. J Clin Endocrinol Metab. 2002, 87 (12): 5524-5531. 10.1210/jc.2002-020575.

Rauk PN, Chiao JP: Interleukin-1 stimulates human uterine prostaglandin production through induction of cyclooxygenase-2 expression. Am J Reprod Immunol. 2000, 43 (3): 152-159. 10.1111/j.8755-8920.2000.430304.x.

Roh CR, Oh WJ, Yoon BK, Lee JH: Up-regulation of matrix metalloproteinase-9 in human myometrium during labour: a cytokine-mediated process in uterine smooth muscle cells. Molecular Human Reproduction. 2000, 6 (1): 96-102. 10.1093/molehr/6.1.96.

Ledingham M, Thomson A, Macara L, Young A, Greer I, Norman J: Changes in the expression of nitric oxide synthase in the human uterine cervix during pregnancy and parturition. Molecular Human Reproduction. 2000, 6: 1041-1048. 10.1093/molehr/6.11.1041.

Tschugguel W, Schneeberger C, Lass H, Stonek F, Zaghlula M, Czerwenka K, Schatten C, Kaider A, Husslein P, Huber J: Human cervical ripening is associated with an increase in cervical inducible nitric oxide synthase expression. Biology of Reproduction. 1999, 60: 1367-1372. 10.1095/biolreprod60.6.1367.

Thomson AJ, Lunan CB, Cameron AD, Cameron IT, Greer IA, Norman JE: Nitric oxide donors induce ripening of the human uterine cervix: a randomised controlled trial. Br J Obstet and Gynaecol. 1997, 104: 1054-1057.

Nicoll AE, Mackenzie F, Greer IA, Norman J: Vaginal application of the nitric oxide donor isosorbide mononitrate for preinduction cervical ripening: a randomised controlled trial to determine effects on maternal and fetal haemodynamics. Am J Obstet Gynecol. 2001, 184: 958-964. 10.1067/mob.2001.111797.

Osman I, MacKenzie F, Norrie J, Murray HM, Greer IA, Norman JE: The "PRIM" study: a randomized comparison of prostaglandin E2 gel with the nitric oxide donor isosorbide mononitrate for cervical ripening before the induction of labor at term. Am J Obstet Gynecol. 2006, 194 (4): 1012-1021. 10.1016/j.ajog.2005.10.812.

Bollapragada S, Mackenzie F, Norrie J, Petrou S, Reid M, Greer I, Osman I, JE N: IMOP: randomised placebo controlled trial of outpatient cervical ripening with isosorbide mononitrate (IMN) prior to induction of labour – clinical trial with analyses of efficacy, cost effectiveness and acceptability. BMC Pregnancy Childbirth. 2006, 6: 25-10.1186/1471-2393-6-25.

Osman I, Young A, Jordan F, Greer IA, Norman JE: Leukocyte density and proinflammatory mediator expression in regional human fetal membranes and decidua before and during labor at term. J Soc Gynecol Investig. 2006, 13 (2): 97-103. 10.1016/j.jsgi.2005.12.002.

Haddad R, Tromp G, Kuivaniemi H, Chaiworapongsa T, Kim YM, Mazor M, Romero R: Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol. 2006, 195 (2): e1-e24. 10.1016/j.ajog.2005.08.057.