Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia

Poston L: Endothelial dysfunction in preeclampsia. Pharmacol Rep 2006, 58:69–74.

McMaster MT, Ahou Y, Fisher SJ: Abnormal placentation and the syndrome of preeclampsia. Semin Nephrol 2004, 24:540–547.

Sharma A, Satyam A, Sharma JB: Leptin, IL-10, and inflammatory markers (TNF-alpha, IL-6 and IL-8) in preeclamptic, normotensive pregnant and healthy nonpregnant women. Am J Reprod Immunol 2007, 58:21–30.

Girardi G, Yarilin D, Thurman JM, et al.: Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction. J Exp Med 2006, 203:2165–2175.

Lee DL, Sturgis LC, Labazi H, et al.: Angiotensin II hypertension is attenuated in interleukin-6 knockout mice. Am J Physiol Heart Circ Physiol 2006, 288:H935–H940.

Gadonski G, LaMarca BB, Sullivan E, et al.: Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin-6. Hypertension 2006, 48:711–716.

LaMarca BB, Cockrell K, Sullivan E, et al.: Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats. Hypertension 2005, 46:82–86.

Maruotti N, Canatore FP, Crivellato E, et al.: Angiogenesis in rheumatoid arthritis. Histol Histopathol 2006, 21:557–566.

Granger JP, LaMarca BBD, Cockrell K, et al.: Reduced uterine perfusion pressure (RUPP) model for studying cardiovascular-renal dysfunction in response to placental ischemia. Methods Mol Med 2006, 122:383–392.

LaMarca BBD, Bennett WA, Alexander BT, et al.: Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor alpha. Hypertension 2005, 46:1022–10225.

Roberts L, LaMarca B, Fournier L, et al.: Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusion. Hypertension 2006, 47:615–618.

Bdolah Y, Sukhatme VP, Karumanchi SA: Angiogenic imbalance in the pathophysiology of preeclampsia: newer insights. Semin Nephrol 2004, 24:548–556.

Shibata E, Rajakumar A, Powers RW, et al.: Soluble fms-like tyrosine kinase 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates: relationship to circulating placental growth factor. J Clin Endocrinol Metab 2005, 90:4895–4903.

Wolf M, Shah A, Lam C, et al.: Circulating levels of the antiangiogenic marker sFLT-1 are increased in first versus second pregnancies. Am J Obstet Gynecol 2005, 193:16–22.

Maynard SE, Venkatesha S, Thadhani R, et al.: Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia. Pediatr Res 2005, 57:1R–7R.

Karumanchi SA, Bdolah Y: Hypoxia and sFlt-1 in preeclampsia: the “chicken-and-egg” question. Endocrinology 2004, 145:4835–4837.

Karumanchi SA, Maynard SE, Stillman IE, et al.: Preeclampsia: a renal perspective. Kidney Int 2005, 67:2101–2113.

Shimizu A, Masuda Y, Mori T, et al.: Vascular endothelial growth factor 165 resolves glomerular inflammation and accelerates glomerular capillary repair in rat anti-glomerular basement membrane glomerulonephritis. J Am Soc Nephrol 2004, 15:2655–2665.

Miyamoto K, Kitamoto Y, Tokunaga H, et al.: Protective effect of vascular endothelial growth factor/vascular permeability factor 165 and 121 on glomerular endothelial cell injury in the rat. Lab Invest 2004, 84:1126–1136.

Hara A, Wada T, Furuichi K, et al.: Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis. Kidney Int 2006, 69:1986–1995.

Bujold E, Romero R, Chaiworapongsa T, et al.: Evidence supporting that the excess of the sVEGFR-1 concentration in maternal plasma in preeclampsia has a uterine origin. J Matern Fetal Neonatal Med 2005, 18:9–16.

Rajakumar A, Michael HM, Rajakumar PA, et al.: Extraplacental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women. Placenta 2005, 26:563–573.

Krysiak O, Bretschneider A, Zhong E, et al.: Soluble vascular endothelial growth factor receptor-1 (sFLT-1) mediates downregulation of FLT-1 and prevents activated neutrophils from women with preeclampsia from additional migration by VEGF. Circ Res 2005, 97:1253–1261.

Nadar SK, Karalis I, Al Yemeni E, et al.: Plasma markers of angiogenesis in pregnancy induced hypertension. Thromb Haemost 2005, 94:1071–1076.

Koyama S, Kimura T, Ogita K, et al.: Transient local overexpression of human vascular endothelial growth factor (VEGF) in mouse feto-maternal interface during midterm pregnancy lowers systemic maternal blood pressure. Hormone and Metabolic Research 2006, 38:619–624.

Thadhani RI, Johnson RJ, Karumanchi SA: Hypertension during pregnancy: a disorder begging for pathophysiological support. Hypertension 2005, 46:1250–1251.

Thadhani R, Mutter WP, Wolf M, et al.: First trimester placental growth factor and soluble fms-like tyrosine kinase 1 and risk for preeclampsia. J Clin Endocrinol Metab 2004, 89:770–775.

Levine RJ, Maynard SE, Qian C, et al.: Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004, 350:672–683.

Nevo O, Soleymanlou N, Wu Y, et al.: Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1. Am J Physiol Regul Integr Comp Physiol 2006, 291:R1085–R1093.

Eubank TD, Roberts R, Galloway M, et al.: GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity 2004, 21:831–842.

Walther T, Wallukat G, Alexander J, et al.: Angiotensin II type 1 receptor agonistic antibodies reflect fundamental alterations in the uteroplacental vasculature. Hypertension 2005, 46:1275–1279.

Hubel CA, Wallukat G, Wolf M, et al.: Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia. Hypertension 2007, 49:612–617.

Zhou CC, Ahmad S, Mi T, et al.: Angiotensin II induces soluble fms-like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy. Circ Res 2007, 100:88–95.

Stennett AK, Khalil RA: Neurovascular mechanisms of hypertension in pregnancy. Curr Neurovasc Res 2006, 3:131–148.

Zhang ZH, Wei SG, Francis J, et al.: Cardiovascular and renal sympathetic activation by blood-borne TNF-alpha in rat: the role of central prostaglandins. Am J Physiol Regul Integr Comp Physiol 2003, 284:R916–R927.

Ye S, Mozayeni P, Gamburd M, et al.: Interleukin-1beta and neurogenic control of blood pressure in normal rats and rats with chronic renal failure. Am J Physiol Heart Circ Physiol 2000; 279:H2786–H2796.

Campese VM, Ye S, Zhong H: Downregulation of neuronal nitric oxide synthase and interleukin-1beta mediates angiotensin II-dependent stimulation of sympathetic nerve activity. Hypertension 2002, 39:519–524.