Inflammatory cells implicated in neoplasia development in idiopathic inflammatory bowel disease

Zhang, 2014, Inflammatory bowel disease: pathogenesis, World J. Gastroenterol., 20, 91, 10.3748/wjg.v20.i1.91 Kim, 2014, Colorectal cancer in inflammatory bowel disease: the risk, pathogenesis, prevention and diagnosis, World J. Gastroenterol., 20, 9872, 10.3748/wjg.v20.i29.9872 Eaden, 2001, The risk of colorectal cancer in ulcerative colitis: a meta-analysis, Gut, 48, 526, 10.1136/gut.48.4.526 Kim, 2009, Trends of ulcerative colitis-associated colorectal cancer in Korea: a KASID study, J. Gastroenterol. Hepatol., 24, 667, 10.1111/j.1440-1746.2008.05730.x Canavan, 2006, Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn's disease, Aliment Pharmacol. Ther., 23, 1097, 10.1111/j.1365-2036.2006.02854.x Ullman, 2011, Intestinal inflammation and cancer, Gastroenterology, 140, 1807, 10.1053/j.gastro.2011.01.057 Itzkowitz, 2004, Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation, Am. J. Physiol. Gastrointest Liver Physiol., 287, G7, 10.1152/ajpgi.00079.2004 Colman, 2016, Histological inflammation increases the risk of colorectal neoplasia in ulcerative colitis: a systematic review, Intest Res., 14, 202, 10.5217/ir.2016.14.3.202 Jess, 2013, Cancer risk in inflammatory bowel disease according to patient phenotype and treatment: a Danish population-based cohort study, Am. J. Gastroenterol., 108, 1869, 10.1038/ajg.2013.249 Velayos, 2006, Predictive and protective factors associated with colorectal cancer in ulcerative colitis: a case-control study, Gastroenterology, 130, 1941, 10.1053/j.gastro.2006.03.028 Soetikno, 2002, Increased risk of colorectal neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis: a meta-analysis, Gastrointest Endosc., 56, 48, 10.1067/mge.2002.125367 Askling, 2001, Family history as a risk factor for colorectal cancer in inflammatory bowel disease, Gastroenterology, 120, 1356, 10.1053/gast.2001.24052 Laine, 2015, SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease, Gastroenterology, 148, 10.1053/j.gastro.2015.01.031 Kornbluth, 2010, Ulcerative colitis practice guidelines in adults: american college of gastroenterology, practice parameters committee, Am. J. Gastroenterol., 105, 501, 10.1038/ajg.2009.727 Mosli, 2014, Histologic evaluation of ulcerative colitis: a systematic review of disease activity indices, Inflamm. Bowel. Dis., 20, 564, 10.1097/01.MIB.0000437986.00190.71 Marchal-Bressenot, 2017, Development and validation of the Nancy histological index for UC, Gut, 66, 43, 10.1136/gutjnl-2015-310187 Mosli, 2017, Development and validation of a histological index for UC, Gut, 66, 50, 10.1136/gutjnl-2015-310393 Geboes, 2000, A reproducible grading scale for histologic assessment of inflammation of ulcerative colitis, Gut, 47, 404, 10.1136/gut.47.3.404 Hartman, 2014, Isocitrate dehydrogenase-1 is mutated in inflammatory bowel disease-associated intestinal adenocarcinoma with low-grade tubuloglandular histology but not in sporadic intestinal adenocarcinoma, Am. J. Surg. Pathol., 38, 1147, 10.1097/PAS.0000000000000239 Yaeger, 2016, Genomic Alterations observed in colitis-associated cancers are distinct from those found in sporadic colorectal cancers and vary by type of inflammatory bowel disease, Gastroenterology, 151, 278, 10.1053/j.gastro.2016.04.001 Robles, 2016, Whole-exome sequencing analyses of inflammatory bowel disease-associated colorectal cancers, Gastroenterology, 150, 931, 10.1053/j.gastro.2015.12.036 Ludwig, 2013, PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis, Virchows Arch., 462, 57, 10.1007/s00428-012-1345-5 Fukushima, 2015, Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line, Cancer Sci., 106, 1000, 10.1111/cas.12703 Guardiola, 2014, Fecal level of calprotectin identifies histologic inflammation in patients with ulcerative colitis in clinical and endoscopic remission, Clin. Gastroenterol. Hepatol., 12, 1865, 10.1016/j.cgh.2014.06.020 Hogberg, 2017, Diagnosing colorectal cancer and inflammatory bowel disease in primary care: The usefulness of tests for faecal haemoglobin, faecal calprotectin, anaemia and iron deficiency. A prospective study, Scand. J. Gastroenterol., 52, 69, 10.1080/00365521.2016.1228120 Beatty, 2010, Vaccine against MUC1 antigen expressed in inflammatory bowel disease and cancer lessens colonic inflammation and prevents progression to colitis-associated colon cancer, Cancer Prev. Res. (Phila), 3, 438, 10.1158/1940-6207.CAPR-09-0194 Kvedaraite, 2016, Tissue-infiltrating neutrophils represent the main source of IL-23 in the colon of patients with IBD, Gut, 65, 1632, 10.1136/gutjnl-2014-309014 Langrish, 2005, IL-23 drives a pathogenic T cell population that induces autoimmune inflammation, J. Exp. Med., 201, 233, 10.1084/jem.20041257 Berendes, 1957, A fatal granulomatosus of childhood: the clinical study of a new syndrome, Minn. Med., 40, 579 Parkos, 2016, Neutrophil-epithelial interactions: a double-edged sword, Am. J. Pathol., 186, 1404, 10.1016/j.ajpath.2016.02.001 Barrie, 2013, Recurrent blood eosinophilia in ulcerative colitis is associated with severe disease and primary sclerosing cholangitis, Dig. Dis. Sci., 58, 222, 10.1007/s10620-012-2329-7 Lang, 2017, HuR small-molecule inhibitor elicits differential effects in adenomatosis polyposis and colorectal carcinogenesis, Cancer Res., 77, 2424, 10.1158/0008-5472.CAN-15-1726 Nishikawa, 2005, IFN-gamma controls the generation/activation of CD4+ CD25+ regulatory T cells in antitumor immune response, J. Immunol., 175, 4433, 10.4049/jimmunol.175.7.4433 Takiguchi, 2012, Reduced production of polymeric immunoglobulin receptor in murine dextran sodium sulfate-induced colitis, J. Oral. Sci., 54, 23, 10.2334/josnusd.54.23 Brandtzaeg, 2006, The B-cell system in inflammatory bowel disease, Adv. Exp. Med. Biol., 579, 149, 10.1007/0-387-33778-4_10 Noronha, 2009, Hyperactivated B cells in human inflammatory bowel disease, J. Leukoc. Biol., 86, 1007, 10.1189/jlb.0309203 Bjerke, 1986, Immunoglobulin- and J chain-producing cells associated with lymphoid follicles in the human appendix, colon and ileum, including Peyer’s patches, Clin. Exp. Immunol., 64, 432 Kaiserling, 2001, Newly formed lymph nodes in the submucosa in chronic inflammatory bowel disease, Lymphology, 34, 22 Yeung, 2000, Gut, 47, 215, 10.1136/gut.47.2.215 Uzzan, 2016, B cell-activating factor (BAFF)-targeted B cell therapies in inflammatory bowel diseases, Dig. Dis. Sci., 61, 3407, 10.1007/s10620-016-4317-9 Lombardi, 2015, Genomic instability and cellular stress in organ biopsies and peripheral blood lymphocytes from patients with colorectal cancer and predisposing pathologies, Oncotarget, 6, 14852, 10.18632/oncotarget.4032 Suzuki, 2014, Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis, PLoS ONE, 9, e88369, 10.1371/journal.pone.0088369 Okamoto, 2016, Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease, J. Gastroenterol., 51, 11, 10.1007/s00535-015-1098-4 Van der Skuis, 2006, Muc-2 deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection, Gastroenterology, 131, 117, 10.1053/j.gastro.2006.04.020 Wehkamp, 2001, NOD2 (CARD 15) mutations in Crohn’s disease are associated with diminished mucosal alpha-defensin expression, Gut, 53, 1658, 10.1136/gut.2003.032805 Cadwell, 2008, A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells, Nature, 456, 259, 10.1038/nature07416 Cadwell, 2009, A common role for Atg16l1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease, Autophagy, 5, 250, 10.4161/auto.5.2.7560 Lv, 2016, Involvement of activated cdc42 kinase 1 in colitis and colorectal neoplasms, Med. Sci. Monit., 7, 4794, 10.12659/MSM.902274 Flood, 2015, Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: diagnostic and therapeutic potential, Clin. Exp. Immunol., 18, 39, 10.1111/cei.12617 De Arcangelis, 2017, Hemidesmosome integrity protects the colon against colitis and colorectal cancer, Gut, 66, 1748, 10.1136/gutjnl-2015-310847 Eck, 2017, Robust microbiota-based diagnostics for inflammatory bowel disease, J. Clin. Microbiol., 55, 1720, 10.1128/JCM.00162-17 Kanauchi, 2013, The new prophylactic strategy for colon cancer in inflammatory bowel disease by modulating microbes, Scand J Gastroenterol, 48, 387, 10.3109/00365521.2012.741617 Uronis, 2009, Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility, PLoS One, 4, e6026, 10.1371/journal.pone.0006026 Kanauchi, 2009, The therapeutic impact of manipulating microbiota in inflammatory bowel disease, Curr. Pharm. Des., 15, 2074, 10.2174/138161209788489195 Francescone, 2015, Cytokines, IBD and colitis-associated cancer, Inflamm. Bowel Dis., 21, 409, 10.1097/MIB.0000000000000236 Waldner, 2014, Master regulator of intestinal disease: IL-6 in chronic inflammation and cancer development, Semin. Immunol., 26, 75, 10.1016/j.smim.2013.12.003 Williams, 2015, The NLRP1 inflammasome attenuates colitis and colitis-associated tumorigenesis, J. Immunol., 194, 3369, 10.4049/jimmunol.1402098