Inflammation biomarkers in sputum for clinical trials in cystic fibrosis: current understanding and gaps in knowledge

Journal of Cystic Fibrosis - Tập 21 - Trang 691-706 - 2022
Agathe Lepissier1,2,3, Charlotte Addy4,5, Kate Hayes4, Sabrina Noel2, Stéphanie Bui6, Pierre-Régis Burgel3,7,8, Lieven Dupont9, Olaf Eickmeier10, Michael Fayon6, Teresinha Leal11, Carlos Lopes12, Damian G. Downey13, Isabelle Sermet-Gaudelus1,2,3,14
1Paediatric Center for Cystic Fibrosis, Centre de Référence Maladies Rares, Mucoviscidose et Maladies Apparentées, Hôpital Necker Enfants Malades 149 rue de Sévres, Paris 75743, France
2INSERM U1151, Institut Necker Enfants Malades, 160 rue de Vaugirard, Paris 75743, France
3European Reference Network (ERN Lung)
4Northern Ireland Clinical Research Facility, Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL
5All Wales Adult Cystic Fibrosis Centre, University Hopsital Llandough, Penlan Road, CF64 2XX
6Université de Bordeaux (INSERM U1045), CHU de Bordeaux, (CIC1401), F-33000 Bordeaux, France
7National Reference Cystic Fibrosis Center and Department of Respiratory Medicine, Cochin Hospital, Assistance Publique Hôpitaux de Paris, Paris, 75014, France
8Institut Cochin, INSERM U1016 and Université de Paris; Paris 75014, France
9University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
10Facharzt für Kinder- und Jugendmedizin, Universitätsklinikum Frankfurt a.M., Johann Wolfgang-Goethe-Universität, Allergologie, Pneumologie & Mukoviszidose, Theodor-Stern-Kai 7, 60590 Frankfurt/Main
11Louvain Toxicology and Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium
12Departamento do Tórax, Hospital de Santa Maria, Lisbon
13Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL
14Service de Pneumologie et Allergologie Pédiatriques, Centre de Ressources et de Compétence de la Mucoviscidose, Hôpital Necker Enfants Malades 149 rue de Sévres, INSERM U1151, Institut Necker Enfants Malades, Université Paris Sorbonne, Paris 75743, France

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Journal of Cystic Fibrosis

Tập 21

691-706

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