Inflammaging and ‘Garb-aging’
Tóm tắt
Từ khóa
Tài liệu tham khảo
Singh, 2011, Inflammatory markers in population studies of aging, Ageing Res. Rev., 10, 319, 10.1016/j.arr.2010.11.002
Roxburgh, 2010, Role of systemic inflammatory response in predicting survival in patients with primary operable cancer, Future Oncol., 6, 149, 10.2217/fon.09.136
Franceschi, 2000, Inflamm-aging. An evolutionary perspective on immunosenescence, Ann. N.Y. Acad. Sci., 908, 244, 10.1111/j.1749-6632.2000.tb06651.x
Franceschi, 2007, Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans, Mech. Ageing Dev., 128, 92, 10.1016/j.mad.2006.11.016
Morrisette-Thomas, 2014, Inflamm-aging does not simply reflect increases in pro-inflammatory markers, Mech. Ageing Dev., 139, 49, 10.1016/j.mad.2014.06.005
Gerli, 2000, Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians, Mech. Ageing Dev., 121, 37, 10.1016/S0047-6374(00)00195-0
Sacheck, 2006, Age specific relationships between exercise-induced IL-6 and oxidative stress, Am. J. Physiol., 291, E340
Varadhan, 2014, Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults, J. Gerontol. A Biol. Sci. Med. Sci., 69, 165, 10.1093/gerona/glt023
Zeng, 2016, Novel loci and pathways significantly associated with longevity, Sci. Rep., 6, 21243, 10.1038/srep21243
Bonafè, 2001, A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity, Eur. J. Immunol., 31, 2357, 10.1002/1521-4141(200108)31:8<2357::AID-IMMU2357>3.0.CO;2-X
Collino, 2013, Metabolic signatures of extreme longevity in northern Italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism, PLoS ONE, 8, e56564, 10.1371/journal.pone.0056564
Montoliu, 2014, Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity, Aging, 6, 9, 10.18632/aging.100630
Franceschi, 2000, The network and the remodeling theories of aging: historical background and new perspectives, Exp. Gerontol., 35, 879, 10.1016/S0531-5565(00)00172-8
Biagi, 2010, Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians, PLoS ONE, 175, e10667, 10.1371/journal.pone.0010667
Rampelli, 2013, Functional metagenomic profiling of intestinal microbiome in extreme ageing, Aging, 5, 902, 10.18632/aging.100623
Ebersole, 2016, Aging, inflammation, immunity and periodontal disease, Periodontology, 72, 54, 10.1111/prd.12135
Franceschi, 2014, Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases, J. Gerontol. A Biol. Sci. Med. Sci., 69, S4, 10.1093/gerona/glu057
Kennedy, 2014, Geroscience: linking aging to chronic disease, Cell, 159, 709, 10.1016/j.cell.2014.10.039
Grignolio, 2014, Towards a liquid self: how time, geography, and life experiences reshape the biological identity, Front. Immunol., 5, 153, 10.3389/fimmu.2014.00153
Bartlett, 2012, The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection, Aging Cell., 11, 912, 10.1111/j.1474-9726.2012.00849.x
Green, 2016, The clearance of dying cells: table for two, Cell Death Differ., 23, 915, 10.1038/cdd.2015.172
Zitvogel, 2010, Decoding cell death signals in inflammation and immunity, Cell, 140, 798, 10.1016/j.cell.2010.02.015
Medina, 2016, Do not let death do us part: ‘find-me’ signals in communication between dying cells and the phagocytes, Cell Death Differ., 23, 979, 10.1038/cdd.2016.13
Nakayama, 2016, Degradation systems and cardiovascular aging, Circ. Res., 118, 1577, 10.1161/CIRCRESAHA.115.307495
Meroni, 2004, Anti-beta 2 glycoprotein I antibodies in centenarians, Exp. Gerontol., 39, 1459, 10.1016/j.exger.2004.08.003
Lisa, 2009, Autoantibodies to poly(ADP-ribose) polymerase in centenarians: a reappraisal of Grabar's hypothesis, Gerontology, 55, 427, 10.1159/000213652
Meroni, 2014, Antiphospholipid syndrome in 2014: more clinical manifestations, novel pathogenic players and emerging biomarkers, Arthritis Res. Ther., 16, 209, 10.1186/ar4549
Gregor, 2011, Inflammatory mechanisms in obesity, Annu. Rev. Immunol., 29, 415, 10.1146/annurev-immunol-031210-101322
Meydani, 2016, Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans, Aging, 8, 1416, 10.18632/aging.100994
Longo, 2016, Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan, Cell Metab., 23, 1048, 10.1016/j.cmet.2016.06.001
Slyskova, 2014, Both genetic and dietary factors underlie individual differences in DNA damage levels and DNA repair capacity, DNA Repair, 16, 66, 10.1016/j.dnarep.2014.01.016
Ingram, 2015, Calorie restriction mimetics: can you have your cake and eat it, too?, Ageing Res. Rev., 20, 46, 10.1016/j.arr.2014.11.005
Zhu, 2016, Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors, Aging Cell, 15, 428, 10.1111/acel.12445
Cuervo, 2014, Chaperone-mediated autophagy: roles in disease and aging, Cell Res., 24, 92, 10.1038/cr.2013.153
Shirakabe, 2016, Aging and autophagy in the heart, Circ Res., 118, 1563, 10.1161/CIRCRESAHA.116.307474
Johnson, 2016, Rapamycin in aging and disease: maximizing efficacy while minimizing side effects, Oncotarget, 10.18632/oncotarget.10381
Chondrogianni, 2010, Proteasome function determines cellular homeostasis and the rate of aging, Adv. Exp. Med. Biol., 694, 38, 10.1007/978-1-4419-7002-2_4
Chondrogianni, 2000, Fibroblast cultures from healthy centenarians have an active proteasome, Exp. Gerontol., 35, 721, 10.1016/S0531-5565(00)00137-6
Mishto, 2006, Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains, Neurobiol. Aging, 27, 54, 10.1016/j.neurobiolaging.2004.12.004
Chondrogianni, 2015, Proteasome activation: an innovative promising approach for delaying aging and retarding age-related diseases, Ageing Res. Rev., 23, 37, 10.1016/j.arr.2014.12.003
Guerrero, 2013, Recent advances in α-synuclein functions, advanced glycation, and toxicity: implications for Parkinson's disease, Mol. Neurobiol., 47, 525, 10.1007/s12035-012-8328-z
Lin, 2009, RAGE signaling in inflammation and arterial aging, Front. Biosci., 14, 1403, 10.2741/3315
Davis, 2011, The inflammasome NLRs in immunity, inflammation, and associated diseases, Annu. Rev. Immunol., 29, 707, 10.1146/annurev-immunol-031210-101405
Anderson, 2013, A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome, PLoS ONE, 8, e67263, 10.1371/journal.pone.0067263
Juranek, 2015, Receptor for advanced glycation end-products in neurodegenerative diseases, Rev. Neurosci., 26, 691, 10.1515/revneuro-2015-0003
Fang, 2010, RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease, FASEB J., 24, 1043, 10.1096/fj.09-139634
Dall’Olio, 2013, N–glycomic biomarkers of biological aging and longevity: a link with inflammaging, Ageing Res. Rev., 12, 685, 10.1016/j.arr.2012.02.002
Jylhävä, 2011, Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: the Vitality 90+ study, Mech. Ageing Dev., 132, 20, 10.1016/j.mad.2010.11.001
Davalos, 2013, p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes, J. Cell Biol., 201, 613, 10.1083/jcb.201206006
Swindell, 2013, Robust shifts in S100a9 expression with aging: a novel mechanism for chronic inflammation, Sci. Rep., 3, 1215, 10.1038/srep01215
Zhang, 2010, Circulating mitochondrial DAMPs cause inflammatory responses to injury, Nature, 464, 104, 10.1038/nature08780
Pinti, 2014, Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for ‘inflamm-aging’, Eur. J. Immunol., 44, 1552, 10.1002/eji.201343921
Shimada, 2012, Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis, Immunity, 36, 401, 10.1016/j.immuni.2012.01.009
Iyer, 2013, Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation, Immunity, 39, 311, 10.1016/j.immuni.2013.08.001
Samy, 2015, DAMPs and influenza virus infection in ageing, Ageing Res. Rev., 24, 83, 10.1016/j.arr.2015.07.005
Salminen, 2012, Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases, Cell. Mol. Life Sci., 69, 2999, 10.1007/s00018-012-0962-0
Balaj, 2011, Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences, Nat Commun., 2, 180, 10.1038/ncomms1180
Kahlert, 2014, Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer, J. Biol. Chem., 289, 3869, 10.1074/jbc.C113.532267
Thakur, 2014, Double-stranded DNA in exosomes: a novel biomarker in cancer detection, Cell Res., 24, 766, 10.1038/cr.2014.44
Chan, 2012, Male microchimerism in the human female brain, PLoS ONE, 7, e45592, 10.1371/journal.pone.0045592
Mittra, 2015, Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes, J. Biosci., 40, 91, 10.1007/s12038-015-9508-6
Jylhävä, 2013, Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty, Aging Cell, 12, 388, 10.1111/acel.12058
Nelson, 2012, A senescent cell bystander effect: senescence induced senescence, Aging Cell, 11, 345, 10.1111/j.1474-9726.2012.00795.x
Acosta, 2013, A complex secretory program orchestrated by the inflammasome controls paracrine senescence, Nat. Cell Biol., 15, 978, 10.1038/ncb2784
Bonafè, 2012, Inflamm-aging of the stem cell niche: breast cancer as a paradigmatic example: breakdown of the multi-shell cytokine network fuels cancer in aged people, Bioessays, 34, 40, 10.1002/bies.201100104
Jurk, 2014, Chronic inflammation induces telomere dysfunction and accelerates ageing in mice, Nat. Commun., 2, 4172, 10.1038/ncomms5172
Cocucci, 2015, Ectosomes and exosomes: shedding the confusion between extracellular vesicles, Trends Cell Biol., 25, 364, 10.1016/j.tcb.2015.01.004
Villeda, 2011, The ageing systemic milieu negatively regulates neurogenesis and cognitive function, Nature, 477, 90, 10.1038/nature10357
Villeda, 2014, Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice, Nat. Med., 20, 659, 10.1038/nm.3569
Ray, 2007, Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins, Nat. Med., 13, 1359, 10.1038/nm1653
Olivieri, 2012, Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging, Mech. Ageing Dev., 133, 675, 10.1016/j.mad.2012.09.004
Olivieri, 2014, Age- and glycemia-related miR-126-3p levels in plasma and endothelial cells, Aging, 6, 771, 10.18632/aging.100693
Ameling, 2015, Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study, BMC Med. Genomics, 8, 61, 10.1186/s12920-015-0136-7
Olivieri, 2015, DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging, Oncotarget, 6, 35509, 10.18632/oncotarget.5899
Olivieri, 2013, MicroRNAs linking inflamm-aging, cellular senescence and cancer, Ageing Res. Rev., 12, 1056, 10.1016/j.arr.2013.05.001
Noren Hooten, 2013, Age-related changes in microRNA levels in serum, Aging, 5, 725, 10.18632/aging.100603
Zhang, 2015, Investigation of microRNA expression in human serum during the aging process, J. Gerontol. A Biol. Sci. Med. Sci., 70, 102, 10.1093/gerona/glu145
Prenderville, 2015, Adding fuel to the fire: the impact of stress on the ageing brain, Trends Neurosci., 38, 13, 10.1016/j.tins.2014.11.001
Ottaviani, 2008, Ecoimmunology: is there any room for the neuroendocrine system?, Bioessays, 30, 868, 10.1002/bies.20801
Franceschi, 2000, Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space, Vaccine, 18, 1717, 10.1016/S0264-410X(99)00513-7
Vitale, 2013, Oxidative stress and the ageing endocrine system, Nat. Rev. Endocrinol., 9, 228, 10.1038/nrendo.2013.29
Ostan, 2015, Inflammaging and cancer: a challenge for the Mediterranean diet, Nutrients, 7, 2589, 10.3390/nu7042589
Shapiro, 2014, The cross talk between microbiota and the immune system: metabolites take center stage, Curr. Opin. Immunol., 30, 54, 10.1016/j.coi.2014.07.003
Rooks, 2016, Gut microbiota, metabolites and host immunity, Nat. Rev. Immunol., 16, 341, 10.1038/nri.2016.42
Claesson, 2012, Gut microbiota composition correlates with diet and health in the elderly, Nature, 488, 178, 10.1038/nature11319
Safdar, 2016, The potential of endurance exercise-derived exosomes to treat metabolic diseases, Nat. Rev. Endocrinol., 12, 504, 10.1038/nrendo.2016.76
Wellen, 2007, Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis, Cell, 129, 537, 10.1016/j.cell.2007.02.049
Snodgrass, 2013, Inflammasome-mediated secretion of IL-1β in human monocytes through TLR2 activation; modulation by dietary fatty acids, J. Immunol., 191, 4337, 10.4049/jimmunol.1300298
Yan, 2013, Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation, Immunity, 38, 1154, 10.1016/j.immuni.2013.05.015
Goldberg, 2015, Drivers of age-related inflammation and strategies for healthspan extension, Immunol. Rev., 265, 63, 10.1111/imr.12295
Ozcan, 2004, Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes, Science, 306, 457, 10.1126/science.1103160
Hu, 2006, Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression, Mol. Cell Biol., 26, 3071, 10.1128/MCB.26.8.3071-3084.2006
Urano, 2000, IRE1 and efferent signaling from the endoplasmic reticulum, J. Cell Sci., 113, 3697, 10.1242/jcs.113.21.3697
Kim, 2014, Endoplasmic reticulum stress is sufficient for the induction of IL-1β production via activation of the NF-κB and inflammasome pathways, Innate Immun., 20, 799, 10.1177/1753425913508593
Eitan, 2016, Impact of lysosome status on extracellular vesicle content and release, Ageing Res. Rev., 10.1016/j.arr.2016.05.001
Weilner, 2016, Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles, Aging, 8, 16, 10.18632/aging.100865
Weiner-Gorzel, 2015, Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells, Cancer Med., 4, 745, 10.1002/cam4.409
Waldera Lupa, 2015, Characterization of Skin aging-associated secreted proteins (SAASP) produced by dermal fibroblasts isolated from intrinsically aged human skin, J. Invest. Dermatol., 135, 1954, 10.1038/jid.2015.120
Zhu, 2015, Inflammation and the depot-specific secretome of human preadipocytes, Obesity, 23, 989, 10.1002/oby.21053
Beer, 2015, Analysis of the secretome of apoptotic peripheral blood mononuclear cells: impact of released proteins and exosomes for tissue regeneration, Sci. Rep., 5, 16662, 10.1038/srep16662
Prattichizzo, 2016, Anti-TNF-α treatment modulates SASP and SASP-related microRNAs in endothelial cells and in circulating angiogenic cells, Oncotarget, 7, 11945, 10.18632/oncotarget.7858
Wang, 2016, The crosstalk of telomere dysfunction and inflammation through cell–free TERRA containing exosomes, RNA Biol., 13, 690, 10.1080/15476286.2016.1203503
Raoof, 2010, Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1, J. Trauma, 68, 1328, 10.1097/TA.0b013e3181dcd28d
Westman, 2015, Extracellular histones induce chemokine production in whole blood ex vivo and leukocyte recruitment in vivo, PLoS Pathog., 11, e1005319, 10.1371/journal.ppat.1005319
Gupta, 2010, CpG oligodeoxynucleotides as TLR9 agonists: therapeutic application in allergy and asthma, BioDrugs, 24, 225, 10.2165/11536140-000000000-00000
Huang, 2013, The role of glycoprotein 96 in the persistent inflammation of rheumatoid arthritis, Arch. Biochem. Biophys., 530, 1, 10.1016/j.abb.2012.12.008
Klink, 2012, The interaction of HspA1A with TLR2 and TLR4 in the response of neutrophils induced by ovarian cancer cells in vitro, Cell Stress Chaperones, 17, 661, 10.1007/s12192-012-0338-2
Fischer, 2007, Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4, Cell Microbiol., 9, 1239, 10.1111/j.1462-5822.2006.00867.x