Induction of contrasuppression is restricted by genes mapping to the Igh locus

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Med.156: 361 (1982). Taniguchi, M.; Tada, T.; Tokuhisa, T.: Properties of the antigen-specific T cell factor in the regulation of antibody response of the mouse. III. Dual gene control to the T cell mediated suppression of the antibody response. J. exp. Med.144: 20 (1976). Yamauchi, K.; Taniguchi, M.; Green, D.R.; Gershon, R.K.: The use of a monoclonal I-J specific antibody to distinguish cells in the feedback suppression circuit from those in the contrasuppression circuit. Immunogenetics16: 551 (1982). Flood, P.M.; Waltenbaugh, C.W.; Tada, T.; Chue, B.; Murphy, D.B.: Serologic heterogenity in I-J determinants associated with functionally distinct T cell regulatory factors. J. Immun.137: 2237 (1986). Yamauchi, K.; Chao, N.; Murphy, D.B.; Gershon, R.K.: Molecular composition of an antigen-specific, Ly-1 T suppressor inducer factor: One molecule binds antigen and is I-J−; another is I-J+ does not bind antigen, and imparts and Igh-variable region linked restriction. J. exp. 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