Induction of chromosomal damage in mammalian cells in vitro and in vivo by sulfapyridine or 5-aminosalicylic acid

Mutation Research Letters - Tập 283 Số 1 - Trang 59-64 - 1992
Karsten Witt1, Jack A. Taylor2, A.F. McFee1, V. Kumaroo3
1Oak Ridge Associated Universities, Oak Ridge, TN, USA
2Experimental Carcinogenesis and Mutagenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
3SITEK Research Laboratory, Rockville, MD, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Bishop, 1990, Evaluation of the mutagenicity of the anti-inflammatory drug salicylazosulfapyridine (SASP), Mutagenesis, 5, 549, 10.1093/mutage/5.6.549

Das, 1974, The role of the colon in the metabolism of salicyla-zosulphapyridine, Scand. J. Gastroenterol., 9, 549, 10.1080/00365521.1974.12096805

Das, 1974, The role of the colon in the metabolism of salicylazosulphapyridine, Scand. J. Gastroenterol., 9, 137, 10.1080/00365521.1974.12096805

Fox, 1987, Abnormal chromosomes and sulfasalazine therapy, 15

Galloway, 1987, Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: evaluations of 108 chemicals, Environ. Mol. Mutagen., 10, 1, 10.1002/em.2850100502

ILS, 1990

Mackay, 1989, In vitro induction of chromosome damage by sulphasalazine in human lymphocytes, Mutation Res., 222, 27, 10.1016/0165-1218(89)90032-3

Margolin, 1983, Statistical analysis and sample size determination for mutagenicity experiments with binomial responses, Environ. Mutagen., 5, 705, 10.1002/em.2860050509