Induction of Nitric Oxide Production by Natural Killer Cells: Its Role in Tumor Cell Death

Nathan, 1992, Nitric oxide as a secretory product of mammalian cells, FASEB J., 6, 3051, 10.1096/fasebj.6.12.1381691 Schmidt, 1994, NO at work, Cell, 23, 919, 10.1016/0092-8674(94)90267-4 Nicotera, 1997, Nitric oxide: Inducer or suppressor of apoptosis, Trends Pharmacol. Sci., 18, 189, 10.1016/S0165-6147(97)90619-2 Stuehr, 1989, Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells, J. Exp. Med., 169, 1543, 10.1084/jem.169.5.1543 Green, 1991, Cytokine-induced synthesis of nitrogen oxides in macrophage: A protective host response to Leishmania and other intracellular pathogens, J. Leukocyte Biol., 50, 93, 10.1002/jlb.50.1.93 Yim, 1993, Macrophage nitric oxide synthesis delays progression of ultraviolet light-induced murine skin cancers, Cancer Res., 53, 5507 Farias-Eisner, 1994, Nitric oxide is an important mediator for tumoricidal activity in vivo, Proc. Natl. Acad. Sci. USA, 91, 9407, 10.1073/pnas.91.20.9407 Brockhaus, 1998, U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation, Exp. Cell Res., 238, 33, 10.1006/excr.1997.3778 Moncada, 1991, Nitric oxide: Physiology, pathophysiology and pharmacology, Pharmacol. Rev., 43, 109 Garside, 1992, Nitric oxide mediates intestinal pathology in graft-vs-host disease, Eur. J. Immunol., 22, 2141, 10.1002/eji.1830220827 Rhoades, 1993, Role of natural killer cells in the pathogenesis of human acute graft-versus-host disease, Transplantation, 56, 113, 10.1097/00007890-199307000-00021 Trinchieri, 1989, Biology of natural killer cells, Adv. Immunol., 47, 187, 10.1016/S0065-2776(08)60664-1 Herberman, 1986, Mechanism of cytotoxicity by natural killer (NK) cells, Rev. Immunol., 4, 651, 10.1146/annurev.iy.04.040186.003251 Shresta, 1995, Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells, Proc. Natl. Acad. Sci. USA, 92, 5679, 10.1073/pnas.92.12.5679 Shi, 1992, A natural killer cell granule protein that induces DNA fragmentation and apoptosis, J. Exp. Med., 175, 553, 10.1084/jem.175.2.553 Ciforne, 1994, Induction of the nitric oxide synthesizing pathway in fresh and interleukin-2 cultured rat natural killer cells, Cell. Immunol., 157, 181, 10.1006/cimm.1994.1215 Park, 1991, Stimulation of lymphocyte natural killer cytotoxicity by l-arginine, Lancet, 337, 645, 10.1016/0140-6736(91)92456-C Hibbs, 1988, Nitric oxide: A cytotoxic activated macrophage effector molecule, Biochem. Biophys. Res. Commun., 157, 87, 10.1016/S0006-291X(88)80015-9 Khar, 1993, Characterization of spontaneous immunological regression in a histiocytoma. I. Role of NK cells and antitumor antibodies, Int. J. Oncol., 2, 393 Khar, 1997, Natural killer cell as the effector which mediates in vivo apoptosis in AK-5 tumor cells, Cell. Immunol., 177, 86, 10.1006/cimm.1997.1095 Bright, 1994, Modulation of natural killer cell function by AK-5, a spontaneously regressing rat histiocytoma, Cell. Immunol., 154, 54, 10.1006/cimm.1994.1056 Green, 1982, Analysis of nitrate, nitrite and [15N]nitrate in biological fluids, Anal. Biochem., 124, 131, 10.1016/0003-2697(82)90118-X Rao, 1992, Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor, Leukocyte Biol., 51, 496, 10.1002/jlb.51.5.496 Bright, 1995, Natural killer cell activation-associated induction of target cell DNA fragmentation in a spontaneously regressing rat histiocytoma, Immunology, 85, 638 Chomzynski, 1987, Single step method of RNA isolation by acid guanidium thiocyanate–phenol–chloroform extraction, Anal. Biochem., 162, 156, 10.1006/abio.1987.9999 Koch, 1986, An improved method for labelling of DNA probes by nick translation, Nucleic Acids Res., 14, 7132, 10.1093/nar/14.17.7132 Filep, 1996, Involvement of nitric oxide in target cell lysis and DNA fragmentation induced by murine natural killer cells, Blood, 87, 5136, 10.1182/blood.V87.12.5136.bloodjournal87125136 Kay, 1983, Evidence for a nonoxidative mechanism of human natural killer (NK) cell cytotoxicity by using mononuclear effector cells from healthy donors and from patients with chronic granulomatous disease, J. Immunol., 131, 1784, 10.4049/jimmunol.131.4.1784 Van de Griend, 1987, Regulation of cytotoxic activity in CD3− and CD3+ killer cell clones by monoclonal antibodies (Anti-CD16, anti-CD2, anti-CD3) depends on subclass specificity of target cell IgG-FcR1, J. Immunol., 138, 3137, 10.4049/jimmunol.138.10.3137 Lowenstein, 1992, Nitric oxide, a novel biologic messenger, Cell, 70, 705, 10.1016/0092-8674(92)90301-R Lincoln, 1993, Intracellular cyclic GMP receptor proteins, FASEB J., 7, 328, 10.1096/fasebj.7.2.7680013 Bhaumik, 1998, Cytokine-induced production of NO by macrophages induces apoptosis and immunological rejection of AK-5 histiocytic tumor, Apoptosis, 3, 361, 10.1023/A:1009685206353 Bhaumik, 1998, Induction of nitric oxide production by the peritoneal macrophages after intraperitoneal or subcutaneous transplantation of AK-5 tumor, Nitric Oxide Biol. Chem., 2, 467, 10.1006/niox.1998.0199 Feelish, 1987, Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase, Eur. J. Pharmacol., 139, 19, 10.1016/0014-2999(87)90493-6 Galli, 1998, S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase decreases the enzyme affinity of the erythrocyte membrane, Nitric Oxide Biol. Chem., 2, 17, 10.1006/niox.1997.0148 Khar, 1986, Development and characterization of rat histiocyte–macrophage tumor cell line, J. Natl. Cancer Inst., 76, 871