Indoor environmental quality and the prevalence of childhood asthma and rhinitis in Wuhan area of China
Tóm tắt
Indoor environmental quality is suspected to be at least part of the cause of the increasing prevalence of childhood asthma and allergy. This study is part of the China, Children, Homes, Health (CCHH) project, which was designed to identify the risk factors indoors that are associated with prevalence of asthma and allergy among children in China. A cross-sectional questionnaire study was carried out in Wuhan in 2011. The questionnaire was a modified (to Chinese building characteristics) version of a questionnaire used first in Sweden. The parents of 2193 children, aged 1–8 years, replied, a response rate of 91.4% (2193/2400). Prevalences of asthma and allergic symptoms were calculated, and a Chi-square test and multiple logistic regression were used to identify risk factors. Prevalences of health outcomes are “wheezing last 12 months” 18.5%, “cough at night last 12 months” 15.4%, “doctor-diagnosed asthma” 6.0%, “rhinitis last 12 months” 48.7%, “doctor-diagnosed allergic rhinitis” 17.5%. Factors associated with increased risk for asthma, allergy and related symptoms include living in an urban area, dampness (significant), use of gas for cooking, new dwelling decoration (paint and furniture obtained during pregnancy), keeping pets and breast feeding less than 3 months. Factors associated with reduced risk as installing an exhaust fan in the bathroom. Home environmental factors are significantly associated with the prevalence of childhood asthma and rhinitis in Wuhan. Urbanization and dampness problems at home are significant risk factors for doctor diagnosed asthma and allergic rhinitis among children in Wuhan.
Tài liệu tham khảo
Asher M I, Montefort S, Bjorksten B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC phases one and three repeat multicountry cross-sectional surveys. Lancet, 2006, 368: 733–743
Ait-Khaled N, Pearce N, Anderson H R, et al. Global map of the prevalence of symptoms of rhinoconjunctivitis in children: The International Study of Asthma and allergies in Childhood (ISAAC) Phase Three. Allergy, 2009, 64: 123–148
Lai C K, Beasley R, Crane J, et a1. Global variation in the prevalence and severity of asthma symptoms: Phase three of the international study of asthma and allergies in childhood (ISAAC). Thorax, 2009, 64: 476–483
Wong G W, Chow C M. Childhood asthma epidemiology: Insights from comparative studies of rural and urban populations. Pediatr Pulm, 2008, 43: 107–116
Bornehag C G, Sundell J, Hagerhed-Engman L, et al. ‘Dampness’ at home and its association with airway, nose, and skin symptoms among 10851 preschool children in Sweden: A cross sectional study. Indoor Air, 2005, 15(Suppl 10): 48–55
Bornehag C G, Sundell J, Weschler C J, et al. The association between asthma and allergic symptoms in children and phthalates in house dust: A nested case-control study. Environ Health Persp, 2004, 112: 1393–1397
Bornehag C G, Sundell J, Hagerhed-Engman L, et al. Association between ventilation rates in 390 Swedish homes and allergic symptoms in children. Indoor Air, 2005, 15: 275–280
Choi H, Schmidbauer N, Sundell J, et al. Common household chemicals and the allergy risks in pre-school age children. PLoS One, 2010, 5: e13423
Hsu N Y, Lee C C, Wang J Y, et al. Predicted risk of childhood allergy, asthma, and reported symptoms using measured phthalate exposure in dust and urine. Indoor Air, 2012, 22: 186–199
Kolarik B, Naydenov K, Larsson M, et al. The association between phthalates in dust and allergic diseases among Bulgarian children. Environ Health Persp, 2008, 116: 98–103
Naydenov K, Popov T, Mustakov T, et al. The association of pet keeping at home with symptoms in airways, nose and skin among Bulgarian children. Pediatr Allergy Immunol, 2008, 19: 702–708
Sun Y, Zhang Y, Sundell J, et al. Dampness at dorm and its associations with allergy and airways infection among college students in China: A cross-sectional study. Indoor Air, 2009, 19: 174–182
Lu H B, Deng F R, Sun J D, et al. The comparison of the indoor environmental factors associated with asthma and related allergies among school-child between urban and suburban arefs in Beijing (in Chinese). Chin J Prev Med, 2010, 44: 626–630
Wang S L, Guo X B, Zhang J L. Study on the effects of ambient air pollution on respiratory disease and symptoms among school-age children in Beijing (in Chinese). J Environ Health, 2004, 21: 41–44
Tham K W, Zuraimi M S, Koh D, et al. Associations between home dampness and presence of molds with asthma and allergic symptoms among young children in the tropics. Pediatr Allergy Immunol, 2007, 18: 418–424
Sun Y, Sundell J. Life style and home environment are associated with racial disparities of asthma and allergy in Northeast Texas children. Sci Total Environ, 2011, 409: 4229–4234
Asher M I, Keil U, Anderson H R, et al. International study of asthma and allergies in childhood (ISAAC): Rationale and methods. Eur Respir J, 1995, 8: 483–491
Cooper P J, Rodrigues L C, Cruz A A, et al. Asthma in Latin America: A public health challenge and research opportunity. Allergy, 2009, 64: 5–17
Aligne C A, Auinger P, Byrd R S, et al. Risk factors for pediatric asthma. Am J Respir Crit Care Med, 2000, 162: 873–877
Sun Y, Zhang Y, Bao L, et al. Ventilation and dampness in dorms and their associations with allergy among college students in China: A case-control study. Indoor Air, 2011, 21: 277–283
Hagerhed-Engman L, Bornehag C G, Sundell J, et al. Day-care attendance and increased risk for respiratory and allergic symptoms in preschool age. Allergy, 2006, 61: 447–453
Hsu N Y, Wu P C, Bornehag C G, et al. Feeding bottles usage and the prevalence of childhood allergy and asthma. Clin Dev Immunol, 2012, doi: 10.1155/2012/158248