Independence and merger of thalamocortical channels within macaque monkey primary visual cortex: Anatomy of interlaminar projections

Visual Neuroscience - Tập 11 Số 3 - Trang 467-489 - 1994
Takashi Yoshioka1, Jonathan B. Levitt2, Jennifer S. Lund2
1Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore
2Department of Visual Science, Institute of Ophthalmology, University of London, Bath St., London EC1V 9EL, England

Tóm tắt

AbstractAn important issue in understanding the function of primary visual cortex in the macaque monkey is how the several efferent neuron groups projecting to extrastriate cortex acquire their different response properties. To assist our understanding of this issue, we have compared the anatomical distribution of VI intrinsic relays that carry information derived from magno- (M) and parvocellular (P) divisions of the dorsal lateral geniculate nucleus between thalamic recipient neurons and interareal efferent neuron groups within area VI. We used small, iontophoretic injections of biocytin placed in individual cortical laminae of area VI to trace orthograde and retrograde inter- and intralaminar projections. In either the same or adjacent sections, the tissue was reacted for cytochrome oxidase (CO), which provides important landmarks for different efferent neuron populations located in CO rich blobs and CO poor interblobs in laminae ⅔, as well as defining clear boundaries for the populations of efferent neurons in laminae 4A and 4B. This study shows that the interblobs, but not the blobs, receive direct input from thalamic recipient 4C neurons; the interblobs receive relays from mid 4C neurons (believed to receive convergent M and P inputs), while blobs receive indirect inputs from either M or P (or both) pathways through layers 4B (which receives M relays from layer 4Cα) and 4A (which receives P relays directly from the thalamus as well as from layer 4Cβ). The property of orientation selectivity, most prominent in the interblob regions and in layer 4B, may have a common origin from oriented lateral projections made by mid 4C spiny stellate neurons. While layer 4B efferents may emphasize M characteristics and layer 4A efferents emphasize P characteristics, the dendrites of their constituent pyramidal neurons may provide anatomical access to the other channel since both blob and interblob regions in layers ⅔ have anatomical access to M and P driven relays, despite functional differences in the way these properties may be expressed in the two compartments.

Từ khóa


Tài liệu tham khảo

10.1002/cne.901460402

Yoshioka, 1993, Anatomical basis for channel interactions in macaque conical visual area VI, Investigative Ophthalmology and Visual Science, 34, 1173

10.1523/JNEUROSCI.12-07-02785.1992

10.1016/0306-4522(84)90006-X

10.1002/cne.901590303

10.1002/cne.902020104

10.1002/cne.901470404

10.1523/JNEUROSCI.07-11-03371.1987

10.1073/pnas.89.8.3566

Yoshioka, 1992, Patterns of lateral connections in macaque visual area VI revealed by biocytin histochemistry and functional imaging, Society for Neuroscience Abstracts, 18, 299

10.1523/JNEUROSCI.04-11-02830.1984

10.1002/cne.903150306

10.1038/304531a0

10.1126/science.7268423

10.1523/JNEUROSCI.10-02-00649.1990

10.1016/0006-8993(91)91344-Z

10.1152/jn.1978.41.6.1394

10.1098/rspb.1977.0085

10.1523/JNEUROSCI.03-04-00673.1983

10.1523/JNEUROSCI.05-12-03350.1985

10.1152/jn.1977.40.2.428

10.1093/cercor/2.1.38

10.1016/0006-8993(79)90485-2

Lund, 1990, Signal and Sense. Local and Global Order in Perceptual Maps, 51

10.1002/cne.903240106

10.1002/cne.901820108

10.1523/JNEUROSCI.04-01-00309.1984

10.1523/JNEUROSCI.05-12-03329.1985

10.1523/JNEUROSCI.03-07-01389.1983

10.1093/cercor/3.2.148

10.1073/pnas.79.19.6098

10.1002/cne.902570106

10.1073/pnas.85.12.4534

10.1523/JNEUROSCI.08-05-01712.1988

10.1002/cne.903110206

10.1002/cne.903420405

10.1523/JNEUROSCI.07-11-03416.1987

10.1002/cne.902760102

10.1523/JNEUROSCI.04-03-00880.1984

Thông tin
Thông tin xuất bản

Visual Neuroscience

Tập 11 Số 3

467-489

Thông tin tác giả