Increased penetration of diphenhydramine in brain via proton-coupled organic cation antiporter in rats with lipopolysaccharide-induced inflammation
Tài liệu tham khảo
Assmann, 2017, Isolation and cultivation of primary brain endothelial cells from adult mice, BIO-PROTOCOL, 7, 10.21769/BioProtoc.2294
Au-Yeung, 2006, A pharmacokinetic study of diphenhydramine transport across the blood-brain barrier in adult sheep: potential involvement of a carrier-mediated mechanism, Drug Metab. Dispos., 34, 955, 10.1124/dmd.105.007898
Auvity, 2017, Diphenhydramine as a selective probe to study H + -antiporter function at the blood–brain barrier: application to [ 11 C]diphenhydramine positron emission tomography imaging, J. Cerebr. Blood Flow Metabol., 37, 2185, 10.1177/0271678X16662042
Bauer, 2007, Tumor necrosis factor α and endothelin-1 increase p-glycoprotein expression and transport activity at the blood-brain barrier, Mol. Pharmacol., 10.1124/mol.106.029512
Bolder, 2006, Heat stress enhances recovery of hepatocyte bile acid and organic anion transporters in endotoxemic rats by multiple mechanisms, Cell Stress Chaperones, 11, 89, 10.1379/CSC-143R.1
Bouw, 1998, Methodological aspects of the use of a calibrator in in vivo microdialysis-further development of the retrodialysis method, Pharm. Res. (N. Y.), 15, 1673, 10.1023/A:1011992125204
Calsolaro, 2016, Neuroinflammation in Alzheimer’s disease: current evidence and future directions, Alzheimer’s Dementia, 12, 719, 10.1016/j.jalz.2016.02.010
Chapy, 2015, Pharmacophore-based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell line, Br. J. Pharmacol., 10.1111/bph.13258
Cherrington, 2004, Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats, Drug Metab. Dispos., 32, 734, 10.1124/dmd.32.7.734
Diao, 2010, Regulation of MRP2/ABCC2 and BSEP/ABCB11 expression in sandwich cultured human and rat hepatocytes exposed to inflammatory cytokines TNF-α, IL-6, and IL-1β, J. Biol. Chem., 10.1074/jbc.M110.107805
DILL, 1949, Biochemical studies on diphenhydramine (benadryl) chemical determination of diphenhydramine, J. Biol. Chem., 179, 395, 10.1016/S0021-9258(18)56849-6
Donner, 2004, Enhanced expression of basolateral multidrug resistance protein isoforms Mrp3 and Mrp5 in rat liver by LPS, Biol. Chem., 385, 10.1515/BC.2004.029
Fisher, 2009, Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats, Eur. J. Pharmacol., 613, 119, 10.1016/j.ejphar.2009.04.002
Foster, 1993, Production of TNF alpha by LPS-stimulated murine, rat and human blood and its pharmacological modulation, Agents Actions, 38, C77, 10.1007/BF01991143
Gasser, 2017, Organic cation transporter 3 (OCT3) is localized to intracellular and surface membranes in select glial and neuronal cells within the basolateral amygdaloid complex of both rats and mice, Brain Struct. Funct., 222, 1913, 10.1007/s00429-016-1315-9
Geier, 2013, Profiling solute carrier transporters in the human blood-brain barrier, Clin. Pharmacol. Ther., 10.1038/clpt.2013.175
Gengo, 1989, The pharmacodynamics of diphenhydramine-induced drowsiness and changes in mental performance, Clin. Pharmacol. Ther., 45, 15, 10.1038/clpt.1989.3
Goralski, 2002, The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules, J. Pharmacol. Exp. Therapeut., 303, 959, 10.1124/jpet.102.038885
Hartmann, 2002, Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia, J. Pharmacol. Exp. Therapeut., 303, 273, 10.1124/jpet.102.039404
Hartmann, 2005, Impact of endotoxin-induced changes in P-glycoprotein expression on disposition of doxorubicin in mice, Drug Metab. Dispos., 33, 820, 10.1124/dmd.104.002568
Hayer-Zillgen, 2002, Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3, Br. J. Pharmacol., 10.1038/sj.bjp.0704785
Heneka, 2015, Neuroinflammation in Alzheimer’s disease, Lancet Neurol., 14, 388, 10.1016/S1474-4422(15)70016-5
Higuchi, 2015, Memantine transport by a proton-coupled organic cation antiporter in hCMEC/D3 cells, an in vitro human blood-brain barrier model, Drug Metabol. Pharmacokinet., 30, 182, 10.1016/j.dmpk.2014.12.006
Ito, 2010, Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine, J. Pharmacol. Exp. Therapeut., 10.1124/jpet.109.163642
Kang, 2006, Neurotoxic pyridinium metabolites OF haloperidol are substrates OF human organic cation transporters, Drug Metab. Dispos., 34, 1145, 10.1124/dmd.105.009126
Kato, 2010, Effects of lipopolysaccharide on P-glycoprotein expression and activity in the liver and kidneys, Eur. J. Pharmacol., 636, 155, 10.1016/j.ejphar.2010.03.024
Kato, 2008, Changes of midazolam pharmacokinetics in Wistar rats treated with lipopolysaccharide: relationship between total CYP and CYP3A2, Innate Immun., 10.1177/1753425908095956
Kawase, 2008, Differences in cytochrome P450 and nuclear receptor mRNA levels in liver and small intestines between SD and DA rats, Drug Metabol. Pharmacokinet., 23, 196, 10.2133/dmpk.23.196
Kawase, 2019, Changes in transporters and metabolizing enzymes in the livers of rats with bile duct ligation, J. Pharm. Pharmaceut. Sci., 22, 457
Kawase, 2014, Distinct alterations in ATP-binding cassette transporter expression in liver, kidney, small intestine, and brain in adjuvant-induced arthritic rats, J. Pharmacol. Sci., 103, 2556, 10.1002/jps.24043
Kawase, 2018, Profiling of hepatic metabolizing enzymes and nuclear receptors in rats with adjuvant arthritis by targeted proteomics, Biopharm Drug Dispos., 39, 308, 10.1002/bdd.2147
Kitamura, 2014, Transport characteristics of tramadol in the blood–brain barrier, J. Pharmacol. Sci., 103, 3335, 10.1002/jps.24129
Kitamura, 2016, Cocktail-dosing microdialysis study to simultaneously assess delivery of multiple organic-cationic drugs to the brain, J. Pharmacol. Sci., 105, 935, 10.1002/jps.24691
Köppel, 1987, Clinical symptomatology of diphenhydramine overdose: an evaluation of 136 cases in 1982 to 1985, J. Toxicol. Clin. Toxicol., 25, 53, 10.3109/15563658708992613
Kubo, 2013, Propranolol transport across the inner blood–retinal barrier: potential involvement of a novel organic cation transporter, J. Pharmacol. Sci., 102, 3332, 10.1002/jps.23535
Kurosawa, 2017, Involvement of proton-coupled organic cation antiporter in varenicline transport at blood-brain barrier of rats and in human brain capillary endothelial cells, J. Pharmacol. Sci., 106, 2576, 10.1016/j.xphs.2017.04.032
Kurosawa, 2018, Expression and functional characterization of drug transporters in brain microvascular endothelial cells derived from human induced pluripotent stem cells, Mol. Pharm., 15, 5546, 10.1021/acs.molpharmaceut.8b00697
Kuwayama, 2008, Uptake of 3,4-methylenedioxymethamphetamine and its related compounds by a proton-coupled transport system in Caco-2 cells, Biochim. Biophys. Acta Biomembr., 1778, 42, 10.1016/j.bbamem.2007.08.023
Lee, 2012, Anti-inflammatory effects of a methanol extract from Pulsatilla koreana in lipopolysaccharide-exposed rats, BMB Rep, 45, 371, 10.5483/BMBRep.2012.45.6.018
Lin, 2010, Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodents, J. Neurochem., 114, 717, 10.1111/j.1471-4159.2010.06801.x
Liu, 2015, Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice, Sci. Rep., 5, 13558, 10.1038/srep13558
Luo, 2014, Transcriptional regulation of the human, porcine and bovine OCTN2 gene by PPARα via a conserved PPRE located in intron 1, BMC Genet., 10.1186/s12863-014-0090-y
Luster, 1994, Endotoxin-induced cytokine gene expression and excretion in the liver, Hepatology, 10.1002/hep.1840190229
McKenna, 2018, Immunotolerant p50/NFκB signaling and attenuated hepatic IFNβ expression increases neonatal sensitivity to endotoxemia, Front. Immunol., 9, 2210, 10.3389/fimmu.2018.02210
Miller, 2008, Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy, Pharmacol. Rev., 10.1124/pr.107.07109
Morimoto, 2008, Oseltamivir (Tamiflu) efflux transport at the blood-brain barrier via P-glycoprotein, Drug Metab. Dispos., 36, 6, 10.1124/dmd.107.017699
Nakazawa, 2010, Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect, J. Pharmacol. Sci., 99, 467, 10.1002/jps.21807
Nežić, 2009, Effect of simvastatin on proinflammatory cytokines production during lipopolysaccharide-induced inflammation in rats, Gen. Physiol. Biophys.
Nicholson, 1983, Antihistamines and sedation, Lancet (London, England), 2, 211, 10.1016/S0140-6736(83)90185-X
Nie, 2005, Transcriptional regulation of murine Slc22a1 (Oct1) by peroxisome proliferator agonist receptor-α and -γ, Am. J. Physiol. Gastrointest. Liver Physiol., 10.1152/ajpgi.00057.2004
Okura, 2008, Involvement of the pyrilamine transporter, a putative organic cation transporter, in blood-brain barrier transport of oxycodone, Drug Metab. Dispos., 36, 10.1124/dmd.108.022087
Okura, 2007, Blood–brain barrier transport of pramipexole, a dopamine D2 agonist, Life Sci., 80, 1564, 10.1016/j.lfs.2007.01.035
Oldendorf, 1981, Clearance of radiolabeled substances by brain after arterial injection using a diffusible internal standard
Oldendorf, 1970, Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard, Brain Res., 24, 372, 10.1016/0006-8993(70)90123-X
Ose, 2008, P-glycoprotein restricts the penetration of oseltamivir across the blood-brain barrier, Drug Metab. Dispos., 36, 427, 10.1124/dmd.107.018556
Pavese, 2006, Microglial activation correlates with severity in Huntington disease: a clinical and PET study, Neurology, 66, 1638, 10.1212/01.wnl.0000222734.56412.17
Perry, 2012, Innate inflammation in Parkinson’s disease, Cold Spring Harb. Perspect. Med., 2, a009373, 10.1101/cshperspect.a009373
Poller, 2010, Regulation of BCRP (ABCG2) and P-Glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier, Cell. Mol. Neurobiol., 10.1007/s10571-009-9431-1
Qin, 2007, Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration, Glia, 55, 453, 10.1002/glia.20467
S, 2017, Hydroalcoholic extract of Stevia rebaudiana bert. leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury in rats, Biomed. Pharmacother., 10.1016/j.biopha.2017.08.082
S, 2009, Penetration of oseltamivir and its active metabolite into the brain after lipopolysaccharide-induced inflammation in mice, J. Pharm. Pharmacol., 61
Sadiq, 2011, Diphenhydramine active uptake at the blood–brain barrier and its interaction with oxycodone in vitro and in vivo, J. Pharmacol. Sci., 100, 3912, 10.1002/jps.22567
Shaffer, 2014, Diphenhydramine has similar interspecies net active influx at the blood-brain barrier, J. Pharmacol. Sci., 10.1002/jps.23927
Shebl, 2010, Comparison of mRNA and protein measures of cytokines following vaccination with human papillomavirus-16 L1 virus-like particles, Cancer Epidemiol. Biomark. Prev., 19, 978, 10.1158/1055-9965.EPI-10-0064
Shimomura, 2013, Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood-brain barrier model, Fluids Barriers CNS, 10, 8, 10.1186/2045-8118-10-8
Somann, 2019, Characterization of plasma cytokine response to intraperitoneally administered LPS & subdiaphragmatic branch vagus nerve stimulation in rat model, PloS One, 14, 10.1371/journal.pone.0214317
Spector, 1988, Transport of amantadine and rimantadine through the blood-brain barrier, J. Pharmacol. Exp. Therapeut., 244, 516
Sung, 2004, Modulation of PPAR in aging, inflammation, and calorie restriction, Journals Gerontol. Ser. A Biol. Sci. Med. Sci., 10.1093/gerona/59.10.B997
Suzuki, 2016, Involvement of a proton-coupled organic cation antiporter in the blood-brain barrier transport of amantadine, Biopharm Drug Dispos., 37, 323, 10.1002/bdd.2014
Uno, 2007, Decreased intestinal CYP3A and P-glycoprotein activities in rats with adjuvant arthritis, Drug Metabol. Pharmacokinet., 22, 313, 10.2133/dmpk.22.313
Virdis, 2005, Cyclooxygenase-2 inhibition improves vascular endothelial dysfunction in a rat model of endotoxic shock: role of inducible nitric-oxide synthase and oxidative stress, J. Pharmacol. Exp. Therapeut., 10.1124/jpet.104.077644
Vos, 1997, Differential effects of nitric oxide synthase inhibitors on endotoxin- induced liver damage in rats, Gastroenterology, 113, 1323, 10.1053/gast.1997.v113.pm9322528
Wang, 2017, Pyrilamine-sensitive proton-coupled organic cation (H+/OC) antiporter for brain-specific drug delivery, J. Contr. Release, 254, 34, 10.1016/j.jconrel.2017.03.034
Wedn, 2020, Nicotine improves survivability, hypotension, and impaired adenosinergic renal vasodilations in endotoxic rats: role of α7-nAChRs/HO-1 pathway, Shock, 53, 503, 10.1097/SHK.0000000000001384
Wedn, 2020, Time and sex dependency of hemodynamic, renal, and survivability effects of endotoxemia in rats, Saudi Pharmaceut. J., 28, 127, 10.1016/j.jsps.2019.11.014
Wen, 2010, Mouse OCTN2 is directly regulated by peroxisome proliferator-activated receptor α (PPARα) via a PPRE located in the first intron, Biochem. Pharmacol., 10.1016/j.bcp.2009.10.002
Wright, 2004, Functional map of TEA transport activity in isolated rabbit renal proximal tubules, Am. J. Physiol. Ren. Physiol., 287, F442, 10.1152/ajprenal.00115.2004
Yao, 1997, Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors, J. Biol. Chem., 272, 17795, 10.1074/jbc.272.28.17795
Yu, 2007, TNF activates P-glycoprotein in cerebral microvascular endothelial cells, Cell. Physiol. Biochem., 20, 853, 10.1159/000110445