Increased frequencies of basophils, type 2 innate lymphoid cells and Th2 cells in skin of patients with atopic dermatitis but not psoriasis

Noda, 2015, The translational revolution and use of biologics in patients with inflammatory skin diseases, J. Allergy Clin. Immunol., 135, 324, 10.1016/j.jaci.2014.11.015

Werfel, 2016, Cellular and molecular immunologic mechanisms in patients with atopic dermatitis, J. Allergy Clin. Immunol., 138, 336, 10.1016/j.jaci.2016.06.010

Lowes, 2014, Immunology of psoriasis, Annu. Rev. Immunol., 32, 227, 10.1146/annurev-immunol-032713-120225

Bonefeld, 2016, The role of innate lymphoid cells in healthy and inflamed skin, Immunol. Lett., 179, 25, 10.1016/j.imlet.2016.01.005

Czarnowicki, 2015, Severe atopic dermatitis is characterized by selective expansion of circulating TH2/TC2 and TH22/TC22, but not TH17/TC17, cells within the skin-homing T-cell population, J. Allergy Clin. Immunol., 136, 104, 10.1016/j.jaci.2015.01.020

Hijnen, 2013, CD8(+) T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-gamma, IL-13, IL-17, and IL-22, J. Invest. Dermatol., 133, 973, 10.1038/jid.2012.456

Nograles, 2009, IL-22-producing T22 T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells, J. Allergy Clin. Immunol., 123, 1244, 10.1016/j.jaci.2009.03.041

Esaki, 2016, Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin, J. Allergy Clin. Immunol., 138, 1639, 10.1016/j.jaci.2016.07.013

Hamilton, 2014, Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis, J. Allergy Clin. Immunol., 134, 1293, 10.1016/j.jaci.2014.10.013

Mashiko, 2015, Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis, J. Allergy Clin. Immunol., 136, 351, 10.1016/j.jaci.2015.01.033

Kim, 2015, Innate lymphoid cells in the skin, J. Invest. Dermatol., 135, 673, 10.1038/jid.2014.401

Roediger, 2013, Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells, Nat. Immunol., 14, 564, 10.1038/ni.2584

Simoni, 2017, Human innate lymphoid cell subsets possess tissue-type based heterogeneity in phenotype and frequency, Immunity, 46, 148, 10.1016/j.immuni.2016.11.005

Borriello, 2014, Basophils and skin disorders, J. Invest. Dermatol., 134, 1202, 10.1038/jid.2014.16

Schwartz, 2016, Basophils in inflammation, Eur. J. Pharmacol., 778, 90, 10.1016/j.ejphar.2015.04.049

Eyerich, 2011, Mutual antagonism of T cells causing psoriasis and atopic eczema, N. Eng. J. Med., 365, 231, 10.1056/NEJMoa1104200

Quaranta, 2014, Allergic contact dermatitis in psoriasis patients: typical, delayed, and non-interacting, PLoS One, 9, e101814, 10.1371/journal.pone.0101814

Quaranta, 2014, Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema, Sci. Transl. Med., 6, 244ra90, 10.1126/scitranslmed.3008946

Kim, 2014, Basophils promote innate lymphoid cell responses in inflamed skin, J. Immunol., 193, 3717, 10.4049/jimmunol.1401307

Wakahara, 2013, Basophils are recruited to inflamed lungs and exacerbate memory Th2 responses in mice and humans, Allergy, 68, 180, 10.1111/all.12072

Sullivan, 2011, Genetic analysis of basophil function in vivo, Nat. Immunol., 12, 527, 10.1038/ni.2036

Muto, 2014, The role of basophils and proallergic cytokines, TSLP and IL-33, in cutaneously sensitized food allergy, Int. Immunol., 26, 539, 10.1093/intimm/dxu058

Otsuka, 2016, Roles of basophils and mast cells in cutaneous inflammation, Semin. Immunopathol., 38, 563, 10.1007/s00281-016-0570-4

Teunissen, 2014, Composition of innate lymphoid cell subsets in the human skin: enrichment of NCR(+) ILC3 in lesional skin and blood of psoriasis patients, J. Invest. Dermatol., 134, 2351, 10.1038/jid.2014.146

Villanova, 2014, Characterization of innate lymphoid cells in human skin and blood demonstrates increase of NKp44+ ILC3 in psoriasis, J. Invest. Dermatol., 134, 984, 10.1038/jid.2013.477

Kim, 2013, TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation, Sci. Transl. Med., 5, 170ra16, 10.1126/scitranslmed.3005374

Salimi, 2013, A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis, J. Exp. Med., 210, 2939, 10.1084/jem.20130351

Bruggen, 2016, In situ mapping of innate lymphoid cells in human skin: evidence for remarkable differences between normal and inflamed skin, J. Invest. Dermatol., 136, 2396, 10.1016/j.jid.2016.07.017

Motomura, 2014, Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation, Immunity, 40, 758, 10.1016/j.immuni.2014.04.013

Xue, 2014, Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells, J. Allergy Clin. Immunol., 133, 1184, 10.1016/j.jaci.2013.10.056

Chang, 2014, Prostaglandin D2 regulates human type 2 innate lymphoid cell chemotaxis, J. Allergy Clin. Immunol., 133, 899, 10.1016/j.jaci.2013.09.020

Halim, 2016, Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses, Nat. Immunol., 17, 57, 10.1038/ni.3294

Gandhi, 2016, Targeting key proximal drivers of type 2 inflammation in disease, Nat. Rev. Drug Discov., 15, 35, 10.1038/nrd4624

Yoshimoto, 2009, Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells, Nat. Immunol., 10, 706, 10.1038/ni.1737

Morita, 2016, Innate lymphoid cells in allergic and nonallergic inflammation, J. Allergy Clin. Immunol., 138, 1253, 10.1016/j.jaci.2016.09.011