Increased expression of PGRN protein in follicular fluid and mRNA in granulosa cells in overweight patients with polycystic ovary syndrome

Danni Zhou1, Saijiao Li1, Wei Li2, Tailang Yin1, Wangming Xu1, Jun Zhang1, Jing Yang1,2
1Reproductive Medical Center, Renmin Hospital of Wuhan University, Hubei Clinic Research Center for Assisted Reproductive Technology and Embryonic Development, JieFang Road 238, Wuhan, 430060, PR China
2Obstetrics and Gynecology department, Renmin Hospital of Wuhan University, JieFang Road 238, Wuhan, 430060, China

Tài liệu tham khảo

Morrison, 2015, Role of macrophage migration inhibitory factor in obesity, insulin resistance, type 2 diabetes, and associated hepatic Co-Morbidities: a comprehensive review of human and rodent studies, Front Immunol, 6, 308, 10.3389/fimmu.2015.00308 Hyejin, 2013, Is insulin resistance an intrinsic defect in asian polycystic ovary syndrome?, Yonsei Med J, 54, 609, 10.3349/ymj.2013.54.3.609 Ehrmann, 1999, Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome, Diabetes Care, 22, 141, 10.2337/diacare.22.1.141 Thozhukat, 2010, Mediators of inflammation in polycystic ovary syndrome in relation to adiposity, Mediators Inflamm, 2010, 60 Spritzer, 2015, Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome, Reproduction, 149, 10.1530/REP-14-0435 Mahadevan, 1990, Relationship of a human oocyte scoring system to oocyte maturity and fertilizing capacity, Int J Fertil, 35, 240 Loret De Mola, 1996, Elevated IL-6 levels in the ovarian hyperstimulation syndrome: ovarian immunohistochemical localization of IL-6 signal, Obstet Gynecol, 87, 581, 10.1016/0029-7844(95)00456-4 Stewart, 1994, LIF and the regulation of the preimplantation development of the mammalian embryo, Mol Reprod Dev, 39, 233, 10.1002/mrd.1080390217 Belayet, 2000, Pharmacologic doses of interleukin 8 suppositories induce follicular maturation in rabbits, Cytokine, 12, 361, 10.1006/cyto.1999.0553 Ledoux, 2006, Adiponectin induces periovulatory changes in ovarian follicular cells, Endocrinology, 147, 5178, 10.1210/en.2006-0679 Santos, 2012, Chapter eight −Adiponectin and reproduction, Vitamins Hormones, 90, 187, 10.1016/B978-0-12-398313-8.00008-7 Matsubara, 2012, PGRN is a key adipokine mediating high fat diet-Induced insulin resistance and obesity through IL-6 in adipose tissue, Cell Metab, 15, 38, 10.1016/j.cmet.2011.12.002 Youn, 2009, Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue, Diabetes, 58, 627, 10.2337/db08-1147 Kessenbrock, 2008, Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin, J Clin Invest, 118, 2438 ESPCW Group, 2004, The Rotterdam ESHRE/ASRM?Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long?term health risks related to polycystic ovary syndrome(PCOS), Hum Reprod, 19, 41, 10.1093/humrep/deh098 Matthews, 1985, Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man, Diabetologia, 28, 412, 10.1007/BF00280883 Chen, 2006, Abnormal glucose tolerance in Chinese women with polycystic ovary syndrome, Hum Reprod, 2027, 10.1093/humrep/del142 Steer, 1992, The cumulative embryo score: a predictive embryo scoring technique to select the optimal number of embryos to transfer in vitro fertilization and embryo transfer programme, Hum Reprod, 7, 117, 10.1093/oxfordjournals.humrep.a137542 Goodarzi, 2006, Diagnosis Epidemiology and genetics of the polycystic ovary syndrome, Best Pract Res Clin Endoerinol Metab, 20, 193, 10.1016/j.beem.2006.02.005 Azziz, 2004, The prevalence and features of the polycystic ovary syndrome in an unselected population, J Clin Endocrinol Metab, 89, 2745, 10.1210/jc.2003-032046 Hart, 2004, Definitions, prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome, Best Pract Res Clin Obstet Gynaecol, 18, 671, 10.1016/j.bpobgyn.2004.05.001 Kaur, 2012, Differential gene expression in granulosa cells from polycystic ovary syndrome patients with and without insulin resistance: identification of susceptibility gene sets through network analysis, J Clin Endocrinol Metab, 97, E2016, 10.1210/jc.2011-3441 Mannerås-Holm, 2011, Adipose tissue has aberrant morphology and function in PCOS: enlarged adipocytes and low serum adiponectin, but not circulating sex steroids, are strongly associated with insulin resistance, J Clin Endocrinol Metab, 96, E304, 10.1210/jc.2010-1290 Cassar, 2015, Biomarkers and insulin sensitivity in women with Polycystic Ovary Syndrome: characteristics and predictivecapacity, Clin Endocrinol, 83, 50, 10.1111/cen.12619 Pasquali, 2013, Glucose intolerance states in women with polycystic ovary syndrome, J Endocrinol Invest, 36, 648, 10.1007/BF03346757 Kelly, 2001, Low grade chronic inflammation in women with polycystic ovarian syndrome, J Clin Endocrinol Metab, 86, 2453, 10.1210/jcem.86.6.7580 Diamanti-Kandarakis, 2008, Defectsin insulin signaling pathways in ovarian steroidogenesis and other tissues in polycystic ovary syndrome (PCOS, J Steroid Biochem Mol Biol, 109, 242, 10.1016/j.jsbmb.2008.03.014 Gonzalez, 1999, Elevated serum levels of tumor necrosis factor α in normal-weight women with polycystic ovary syndrome, Metabolism, 48, 437, 10.1016/S0026-0495(99)90100-2 Toulis, 2009, Adiponectin levels in women with polycystic ovary syndmme: a systematic review and a meta-analysis, Hum Reprod Update, 15, 297, 10.1093/humupd/dmp006 Qiao, 2011, Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence, Hum Reprod Update, 17, 17, 10.1093/humupd/dmq032 Wei, 2011, Abnormal expression of growth differentiation factor 9 and bone morphogenetic protein 15 in stimulated oocytes during maturation from women with polycystic ovary syndrome, Fertil Sterility, 96, 464, 10.1016/j.fertnstert.2011.05.036 Mclane, 2014, Are there benefits of smoking reduction during pregnancy? smoking status of pregnant women and the effect on pre-Term delivery, Ajp Regulatory Integrative & Comparative Physiology, 288, 1220 Tsatsanis, 2005, Adiponectin induces TNF-alpha and IL-6 in macrophages and promotes tolerance to itself and other pro-inflammatory stimuli, Biochem Biophys Res Commun, 335, 1254, 10.1016/j.bbrc.2005.07.197 Liu, 2011, Progranulin: a promising therapeutic target for rheumatoid arthritis, FEBS Lett, 585, 3675, 10.1016/j.febslet.2011.04.065 Webber, 2003, Formation and early development of follicles in the polycystic ovary, Lancet, 362, 1017, 10.1016/S0140-6736(03)14410-8 Shi, 2015, Expression of CD11c + HLA-DR + dendritic cells and related cytokines in the follicular fluid might be related to pathogenesis of ovarian hyperstimulation syndrome, Int J Clin Exp Pathol, 8, 15133 Vural, 2010, Tumor necrosis factor alpha, interleukin-6 and interleukin-10 gene polymorphisms in polycystic ovary syndrome, Eur J Obstet Gynecol Reprod Biol, 150, 61, 10.1016/j.ejogrb.2010.02.010 Samy, 2009, Clinical significance of inflammatory markers in polycystic ovary syndrome: their relationship to insulin resistance and body mass index, Dis Mark, 26, 163, 10.1155/2009/465203 Galic, 2010, Adipose tissue as an endocrine organ, Mol Cell Endocrinol, 316, 129, 10.1016/j.mce.2009.08.018 Amato, 2003, Serum and follicular fluid cytokines in polycystic ovary syndrome during stimulated cycles, Obstet Gynecol, 101, 1177 Kim, 2011, Pioglitazone treatment decreases follicular fluid levels of tumor necrosis factor-a and interleukin-6 in patients with polycystic ovary syndrome, Clin Exp Reprod Med, 38, 98, 10.5653/cerm.2011.38.2.98 Ersoy, 2016, Are progranulin levels associated with polycystic ovary syndrome and its possible metabolic effects in adolescents and young women?, Arch Gynecol Obstet, 104, 1 Tang, 2011, The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice, Science, 332, 478, 10.1126/science.1199214 Jian, 2013, Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains, FEBS Lett, 587, 3428, 10.1016/j.febslet.2013.09.024 Zhu, 2002, Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair, Cell, 111, 867, 10.1016/S0092-8674(02)01141-8 Li, 2014, Circulating PGRN is significantly associated with systemic insulin sensitivity and autophagic activity in metabolic syndrome, Endocrinology, 155, 3493, 10.1210/en.2014-1058