Increased cholesterol efflux capacity in metabolic syndrome: Relation with qualitative alterations in HDL and LCAT

Atherosclerosis - Tập 242 - Trang 236-242 - 2015
Diego Lucero1,2, Denis Sviridov2, Lita Freeman2, Graciela I. López1, Eduardo Fassio3, Alan T. Remaley2, Laura Schreier1
1Laboratory of Lipids and Atherosclerosis, Department of Clinical Biochemistry, Faculty of Pharmacy and Biochemistry, INFIBIOC, University of Buenos Aires, Argentina
2Lipoprotein Metabolism Section, National Heart, Lung, Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
3Department of Gastroenterology, National Hospital “Prof. A. Posadas”, Buenos Aires, Argentina

Tài liệu tham khảo

Camont, 2011, Biological activities of HDL subpopulations and their relevance to cardiovascular disease, Trends Mol. Med., 17, 594, 10.1016/j.molmed.2011.05.013 Gordon, 1977, High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study, Am. J. Med., 62, 707, 10.1016/0002-9343(77)90874-9 Cuchel, 2006, Macrophage reverse cholesterol transport: key to the regression of atherosclerosis?, Circulation, 113, 2548, 10.1161/CIRCULATIONAHA.104.475715 Phillips, 2014, Molecular mechanisms of cellular cholesterol efflux, J. Biol. Chem., 289, 24020, 10.1074/jbc.R114.583658 Khera, 2011, Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis, N. Engl. J. Med., 364, 127, 10.1056/NEJMoa1001689 Rohatgi, 2014, HDL cholesterol efflux capacity and incident cardiovascular events, N. Engl. J. Med., 371, 2383, 10.1056/NEJMoa1409065 Li, 2013, Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks, Arterioscler. Thromb. Vasc. Biol., 33, 1696, 10.1161/ATVBAHA.113.301373 Alberti, 2009, Circulation, 120, 1640, 10.1161/CIRCULATIONAHA.109.192644 Carr, 2004, Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk, J. Clin. Endocrinol. Metab., 89, 2601, 10.1210/jc.2004-0432 Kunnen, 2012, Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis?, J. Lipid Res., 53, 1783, 10.1194/jlr.R024513 Assmann, 1983, Quantification of high density lipoprotein cholesterol by precipitation with phosphotungstic acid-MgCl2, Clin. Chem., 29, 2026, 10.1093/clinchem/29.12.2026 Assmann, 1984, LDL (low density lipoprotein) cholesterol determination in blood serum following precipitation of LDL with polyvinyl sulphate, Clin. Chim. Acta, 140, 77, 10.1016/0009-8981(84)90153-0 Matthews, 1985, Homeostasis assessment model: insulin and beta-cell function from fasting plasma glucose and insulin concentrations in man, Diabetologia, 28, 412, 10.1007/BF00280883 Vaughan, 2003, ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions, J. Lipid Res., 44, 1373, 10.1194/jlr.M300078-JLR200 Sankaranarayanan, 2009, Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux, J. Lipid Res., 50, 275, 10.1194/jlr.M800362-JLR200 Asztalos, 1993, Two-dimensional electrophoresis of plasma lipoproteins: recognition of new apo A-I-containing subpopulations, Biochim. Biophys. Acta, 1169, 291, 10.1016/0005-2760(93)90253-6 Asztalos, 2011, Metabolic and functional relevance of HDL subspecies, Curr. Opin. Lipidol., 22, 176, 10.1097/MOL.0b013e3283468061 Freeman, 2013, Native-native 2D gel electrophoresis for HDL subpopulation analysis, 1027, 353 Schumaker, 1986, Sequential flotation ultracentrifugation, Methods Enzymol., 128, 155, 10.1016/0076-6879(86)28066-0 Li, 1994, Analysis of high density lipoproteins by a modified gradient gel electrophoresis method, J. Lipid Res., 35, 1698, 10.1016/S0022-2275(20)41167-8 Rader, 2012, The not-so-simple HDL story: is it time to revise the HDL cholesterol hypothesis?, Nat. Med., 18, 1344, 10.1038/nm.2937 Yassine, 2014, Enhanced cholesterol efflux to HDL through the ABCA1 transporter in hypertriglyceridemia of type 2 diabetes, Metabolism, 63, 727, 10.1016/j.metabol.2014.03.001 Vaughan, 2009, ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation, J. Lipid Res., 50, 285, 10.1194/jlr.M800366-JLR200 Aicher, 2012, Diet-induced weight loss in overweight or obese women and changes in high-density lipoprotein levels and function, Obes. (Silver Spring), 20, 2057, 10.1038/oby.2012.56 Zheng, 2004, Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease, J. Clin. Invest., 114, 529, 10.1172/JCI200421109 Francis, 1993, Oxidative tyrosylation of high density lipoprotein by peroxidase enhances cholesterol removal from cultured fibroblasts and macrophage foam cells, Proc. Natl. Acad. Sci. U. S. A., 90, 6631, 10.1073/pnas.90.14.6631 Nestel, 2012, Cholesterol efflux from macrophages is influenced differentially by plasmas from overweight insulin-sensitive and -resistant subjects, Int. J. Obes. (Lond.), 36, 407, 10.1038/ijo.2011.170 de la Llera-Moya, 2010, The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages, Arterioscler. Thromb. Vasc. Biol., 30, 796, 10.1161/ATVBAHA.109.199158 Tian, 2006, Alterations of high density lipoprotein subclasses in obese subjects, Lipids, 41, 789, 10.1007/s11745-006-5032-7 Sethi, 2010, High pre-beta1 HDL concentrations and low lecithin: cholesterol acyltransferase activities are strong positive risk markers for ischemic heart disease and independent of HDL-cholesterol, Clin. Chem., 56, 1128, 10.1373/clinchem.2009.139931 Kane, 2012, Prebeta-1 HDL and coronary heart disease, Curr. Opin. Lipidol., 23, 367, 10.1097/MOL.0b013e328353eef1 Rye, 2004, Formation and metabolism of prebeta-migrating, lipid-poor apolipoprotein A-I, Arterioscler. Thromb. Vasc. Biol., 24, 421, 10.1161/01.ATV.0000104029.74961.f5 Pirillo, 2013, High-density lipoprotein subfractions–what the clinicians need to know, Cardiology, 124, 116, 10.1159/000346463 Kathiresan, 2006, Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study, Circulation, 113, 20, 10.1161/CIRCULATIONAHA.105.567107 Lagos, 2009, Alterations in the high density lipoprotein phenotype and HDL-associated enzymes in subjects with metabolic syndrome, Lipids, 44, 9, 10.1007/s11745-008-3251-9 Tall, 1998, An overview of reverse cholesterol transport, Eur. Heart J., 19, 31 Tsai, 2009, Associations of genetic variants in ATP-binding cassette A1 and cholesteryl ester transfer protein and differences in lipoprotein subclasses in the multi-ethnic study of atherosclerosis, Clin. Chem., 55, 481, 10.1373/clinchem.2008.107995 Gómez Rosso, 2008, Alterations in cell adhesion molecules and other biomarkers of cardiovascular disease in patients with metabolic syndrome, Atherosclerosis, 199, 415, 10.1016/j.atherosclerosis.2007.11.007 Benítez, 2008, Endothelial and leukocyte adhesion molecules in primary hypertriglyceridemia, Atherosclerosis, 197, 679, 10.1016/j.atherosclerosis.2007.04.005 Dullaart, 2008, Plasma lecithin: cholesterol acyltransferase activity is elevated in metabolic syndrome and is an independent marker of increased carotid artery intima media thickness, J. Clin. Endocrinol. Metab., 93, 4860, 10.1210/jc.2008-1213 Calabresi, 2009, Functional LCAT is not required for macrophage cholesterol efflux to human serum, Atherosclerosis, 204, 141, 10.1016/j.atherosclerosis.2008.08.038 Voight, 2012, Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study, Lancet, 380, 572, 10.1016/S0140-6736(12)60312-2 Schwartz, 2012, Effects of dalcetrapib in patients with a recent acute coronary syndrome, N. Engl. J. Med., 367, 2089, 10.1056/NEJMoa1206797